3JBR


Conserved Protein Domain Family
VGCC_beta4Aa_N

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pfam12052: VGCC_beta4Aa_N 
Voltage gated calcium channel subunit beta domain 4Aa N terminal
The beta subunit of voltage gated calcium channels is coded for by four genes 1-4. Gene 4 can produce two types of beta4A domain (beta4Aa and beta4Ab) according to how the gene splicing is carried out. This family is part of the beta4Aa N terminal domain. It is made up of an alpha helix and a beta strand. It is thought to regulate the channel properties through protein-protein interactions with non Ca channel proteins.
Statistics
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PSSM-Id: 403316
View PSSM: pfam12052
Aligned: 13 rows
Threshold Bit Score: 64.8859
Threshold Setting Gi: 1024969501
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3JBR_B         4 GSADSYTSRPS-DSDV-SLEE-DREAVRREAERQAQAQLEKAKTK 45 
EEN54425      28 GSAESYNSRPS-ESDIsSQDE-DREALRRESEKQALTQLEKARTK 70  Florida lancelet
XP_015782172   4 GSADSNYSQLS--SDL-SLDE-EREAIGRETERQAFAQLEKARSK 44  two-spotted spider mite
XP_009017056  15 GSFESNCSQNS--SNL-SLEE-EQESIRKNAEKLAQTMLEKARTK 55  Helobdella robusta
EEC14293       9 GSADSNYSQPS--SDL-SLDE-DRENTRRETERLALAKLQSAREK 49  black-legged tick
EGT32535       7 GSGDSNFSHHD---EL-ELEAgNRETLRRDAERQAALQLERAKYK 47  Caenorhabditis brenneri
PNI85963      16 GSADSYTSRPS-DSDV-SLEE-DREAIRQEREQQAAIQLERA--K 55  chimpanzee
XP_016306102  16 GSADSYTSRPS-DSDV-SLDE-E-QGGRQEKEQQATIQLERAKAK 56  Sinocyclocheilus anshuiensis
XP_012811902  14 GSADSYTSRPSlDSDV-SLEE-DRETARREVERQAQEQLERARLK 56  tropical clawed frog
CAF93659       2 GSADSYTSRPS-DSDL-SAEE-DREACRREAERQAQLQLDRAKSK 43  spotted green pufferfish
XP_005991485  16 GSADSCTSRPSlDSDV-SLEE-DREVVRRDAEQHALLQLERAKSK 58  coelacanth
XP_028035687  24 GSAESNCSQPS--SEL-SLDD-DKEALRREKEAQALSQLDKARSK 64  wild silkworm
XP_031409913  16 GSADSYTSRPS-DSDV-SLEE-DREAVRREAERQAQAQLEKAKVR 57  turkey
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