Conserved Protein Domain Family
CfaA_B_C
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pfam11912: CfaA_B_C 
Counting factor-associated protein A/B/C
Developing Dictyostelium (Slime mold) cells form large aggregation streams that break up into groups of cells. Each group then becomes a fruiting body. Cells sense if there are too many cells in a stream by sensing the concentration of counting factor (CF), a protein complex secreted by the aggregating cells. This entry includes counting factor-associated protein A/B/C from Slime mold.
Links
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Statistics
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PSSM-Id: 256719
Aligned: 51 rows
Threshold Bit Score: 36.3266
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q86KU5   1 MRL---------SGILLLLSAFAg---------------iINSQY-----------VLVE-EFQy--qGGSCSgsqssid 42  Dictyostelium discoideum
Q55GM4   1 MKI---------ILLILIIISVYnitpnfstsiisnnrisLSTSSsssssslnkkyIVQK-GYNf--iDDKCS------- 61  Dictyostelium discoid...
Q557A0   1 MKFfi------lIFICLMVTTYV-----------------FGFKY-----------TKIE-VHNl--yDDNCS------- 36  Dictyostelium discoid...
Q54LZ4   1 MRLii-----sfVILLVSIVCILsielrnd---ssytssdASSTT-----------YNWL-KTEmytnSNTCE------- 53  Dictyostelium discoid...
Q75JT0   1 MKIlf-----qfIFLSLLFKS-------------------IYSGY-----------LKVE-YYQi--nDYSCK------- 35  Dictyostelium discoideum
Q7KWL7   1 MKQqqylllspiLIIILFINI-------------------IKGGY-----------VSIQ-YFN----NDQCD------- 38  Dictyostelium discoideum
Q54Y65   3 RKLi-------lFLLSFIFINF------------------VKCGY-----------IHMQ-MFAd--aDGLCK------- 36  Dictyostelium discoid...
Q86KQ8   1 MKFlt-----flVLILVSVNNFYl---------------sSGESV-----------ISIK-TFQy--dQYRCRdsdssgl 46  Dictyostelium discoideum
Q54X38   1 MKLlf-----slIALIFLFVNIV-----------------YSESL-----------LSLK-TFQy--dVVGCNkphss-- 42  Dictyostelium discoid...
Q86HB8   1 MKVl-------iLLVSLISVCFSq----------------IAPKP-----------IIVGgVYRg---GETCN------- 36  Dictyostelium discoideum

Q86KU5  43 sqssfdsqsswgsqsswgsqsswgsqsSWASQSSWGssdssnflTASEs-----SGEaCPSSSiggnivqegvcfyyADR 117 Dictyostelium discoideum
Q55GM4  62 ---------------------------EEVVNTVYS------------------IDNaCYFGN----------------- 79  Dictyostelium discoid...
Q557A0  37 ---------------------------LQPYEIVYQ------------------LNGwCVDGN----------------- 54  Dictyostelium discoid...
Q54LZ4  54 ---------------------------GDLLSAAYL------------------KTGiCGFEG----------------- 71  Dictyostelium discoid...
Q75JT0  36 ---------------------------NGMTLVHYR------------------TTNlCNEGT----------------S 54  Dictyostelium discoideum
Q7KWL7  39 ----------------------------QVNFINYF------------------LEGsCVQEQ----------------- 55  Dictyostelium discoideum
Q54Y65  37 -------------------------------DLFIG--------AYVL------EGV-CIENV----------------- 53  Dictyostelium discoid...
Q86KQ8  47 gpmstgsf-----atdermlnlgnidgGNSQSASWSssiqdcdnSEIEnelfvvVGE-CLLMDnd-----------nYYY 109 Dictyostelium discoideum
Q54X38  43 ----------------------sdsqgSLTGSGSFSlleenkrlGSVDgggvlpGSEsSFESLcdnge-----lvteTYI 95  Dictyostelium discoid...
Q86HB8  37 ---------------------------SLQPPYTCS--------SDDLaggimmRQGaCTYFRgl-----------sNLP 70  Dictyostelium discoideum

Q86KU5 118 LPSIYTVSGDNIVQTFYNQt------DYNCe--GKPIDT--VTAV-SGDCYS-ACNQGTGITFQLSAVA-TPVIp----T 180 Dictyostelium discoideum
Q55GM4  80 --VFTCRDDGKIIYDMYEG--------YNCn--GSIVFS--MVIE-NDVCDT---NSSQSYPTVYSCVD-SIEI-----P 135 Dictyostelium discoid...
Q557A0  55 -TNIECNEDGTVITQNVFGt------NSGCk--GAKTGN--ITNA-SGTCAF--------ENVVYSCVD-DFEI-----P 108 Dictyostelium discoid...
Q54LZ4  72 ISRVVCLEDGSIENIIYSK--------QGCt--GDIKER--IRVE-QNNCTN---------SEKYICTE-SIEI-----P 123 Dictyostelium discoid...
Q75JT0  55 LMYTCDAANNNITRTQYYG--------SNC---QGGSES--INLE-ANKCTN---DFGTSNNVIYSCTE-DYDL-----G 111 Dictyostelium discoideum
Q7KWL7  56 --VMKCNSDKSMIEYNIYE---------SCsgnQEPIGT--KQIPtNTSCET--------SAAIYSCIDeLPNLspsadE 114 Dictyostelium discoideum
Q54Y65  54 --IMKCSTNQKSVLAYQYE-------NDDCs--GPIINH--EELV-TGGCVN--------VSSKFECTE-EIDL-----P 105 Dictyostelium discoid...
Q86KQ8 110 YIYRVDYANGTISKTAYTE--------DRC---QTFYSI--EHFK-IDECVMdCKLSGS-YIYTIIDSS-EIVI-----P 168 Dictyostelium discoideum
Q54X38  96 RLDTCIVSTGETYSIDFDNgtikktsAAQCg--EEGIIQwfKPYEcVNDCLSs------pYMYTVIEMD-DIEI-----P 161 Dictyostelium discoid...
Q86HB8  71 TTYNSSSDGSSVIQYTYSAd------DYFCq--ESPIQT--QTIS-NGDCEAgCSNDKISYLYNLSSDS-NDQV-----P 133 Dictyostelium discoideum

Q86KU5 181 TNTI-VEAVYTG----ECNGNyk---nSFVSVYYKSLNTCndnvVAQ---QGTFSFEISCNSt-SS-AVTIFG--NDDCG 245 Dictyostelium discoideum
Q55GM4 136 TSGF-LVYTSQDd---DCGSKe-----DLVNLEITPLNTC----INE---DQTYSFIQTCNSt-NY-STTKYF--GTSCK 195 Dictyostelium discoid...
Q557A0 109 ENTL-VSVVTNG----KCENDpsw-kdDIGLIGYEYLNQC----IQ----NYKGAFELTCNS--SI-PYKNIYnsTSVCN 171 Dictyostelium discoid...
Q54LZ4 124 SNTY--QVWYTHs---TCENDnw--keDVWQMEYILLNTC----LF----SNAGSNMLQCNStlAY-ENIYNS--TNTCN 185 Dictyostelium discoid...
Q75JT0 112 TNSL-VEYLTNG----QCPDSnpawkdDIIQVASLGLNIC----TYT---DVGSIKTTSCNEt-SYdENYYFS--TDSCT 176 Dictyostelium discoideum
Q7KWL7 115 NNFV-TTVIFNGs---DCYNYni---nNIQYVEQQPTGQC----DY----DGAFGSIITCTPt-KFiKQRYEG--SNFCI 176 Dictyostelium discoideum
Q54Y65 106 QDTNtIIIVSHNstqeECPDYk----qGLVKLSYQMTNLC----LPNiikPNQFSTIQTCDEt-SI-TQTNYQ--SRDCN 173 Dictyostelium discoid...
Q86KQ8 169 KDTL-VVFDYTG----ECGGNwk---qTFTTIRYTPINRC----LLT---SESTAYQVTCNSt-NFdQYYSHN--QNNCI 230 Dictyostelium discoideum
Q54X38 162 KDTY-VEIQYHG----DCNNNgw--kqNFDYIKFTPLNQC----FAN---GLSSSYSLNCNT--TMlEITQSD--KFNCL 223 Dictyostelium discoid...
Q86HB8 134 KNAV-LTIKSQSs---NCATDwe---tTWESIEYLNTDTC----IVDe--VTGGSFKVSCTQg-GM-TIYSYA--APGCT 196 Dictyostelium discoideum

Q86KU5 246 GSPVyslhepMVnQCG--DQYNVIEV-CYN 272 Dictyostelium discoideum
Q55GM4 196 GGPIgha-qgEI-TCR--LNNPNQYS-SQY 220 Dictyostelium discoideum AX4
Q557A0 172 TVPTgyg-wfSPnECS--KNDPTFYY-CNV 197 Dictyostelium discoideum AX4
Q54LZ4 186 SSNQtgykfiTLpECS--KKSPVFSI-CDN 212 Dictyostelium discoideum AX4
Q75JT0 177 NAIFsh--alEFpECS--QNTPEIYY-CNN 201 Dictyostelium discoideum
Q7KWL7 177 NPPTnnytytLPiNDCsfNGYNIIQF-CNS 205 Dictyostelium discoideum
Q54Y65 174 PSTK------NQpNINplPVNDCKNS-TNY 196 Dictyostelium discoideum AX4
Q86KQ8 231 RYTYseffktGVqYC---QEFNQQVF-CNL 256 Dictyostelium discoideum
Q54X38 224 VYKDliytdiWG-DCT--GSAEKYINvCNK 250 Dictyostelium discoideum AX4
Q86HB8 197 NNPKvygvgfYTdSCD------GYQV-CSL 219 Dictyostelium discoideum
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