Conserved Protein Domain Family
DUF3376

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pfam11856: DUF3376 
Protein of unknown function (DUF3376)
This family of proteins are functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 770 to 1142 amino acids in length.
Statistics
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PSSM-Id: 371765
View PSSM: pfam11856
Aligned: 9 rows
Threshold Bit Score: 259.627
Threshold Setting Gi: 521300378
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CAM00375           337 LDALDEHNRVVERTGL---------------------RRRAL------FaRLRAAEPAERQDLLVREA----AEVETEHA 385  Saccharo...
WP_020464646       371 LRRIRDHNEAVRGVRA---------------------SRRGL------F-RLAPAGGPRLADEAIYEAyr-hREAERAAD 421  Frankia ...
Q0RUJ2             418 LAALREHNEAVRGARA---------------------GRRRL------L-RLAPAGSARLADDSVYDAyr-rAVAEQIAV 468  Frankia ...
Q2JGZ6             364 LATLRDHNSAVRGTRA---------------------NRRRL------L-RLAPAGGPRLADESVYDAyr-rSLAEEIAP 414  Frankia ...
jgi:Franean1_2668  386 LQQLQETNDRVRRHRS---------------------GRAHL------IgSLDEKLAGQLMDQ--YRTmrscQEADRIGA 436  Frankia ...
Q7NJB7             395 atgqvnylywrirLVT---------------------LRDRVlpvilrLeEQKTAGQAKAQEQTLNKA------ADLLTS 447  Gloeobac...
WP_011748895       333 IRAIARMNRRLERLGAlqnrwredqnrveaagrkmrqRRKPVdldrmdLaDLMTGAFQYPQNYPLYHHlrvyGTTDGLSA 412  Paracocc...
Q01WF4             425 ESADQFAGKKLTELGD---------------------SRGPL--------------------YAGYHRlkikTVTDGLCS 463  Candidat...
jgi:Cpha266_1052   482 fwkaiiadnkkqgdagakkalkkldertldnialladksdvedtpgfitqdlndlialygdgysayhytrmsALDDLLTL 561  Chlorobi...
CAM00375           386 VVRCEL--------------DAQAvrrLLEEPAGT-ED--------------GRLlpPVPGDPLAGWsararhllgrRLS 436  Saccharo...
WP_020464646       422 VVLSTLdrivtg---anagaDAAA---LLADPAGR-TDlraaavtaalaefpDRL--PGPDDLGDLW----------RLG 482  Frankia ...
Q0RUJ2             469 PVIEALlrvltdrsdlprppDADA---LRTDAAGR-AQmtnaavgavlttlpGRL--PGVGDLDELW----------RLG 532  Frankia ...
Q2JGZ6             415 PVIEALlrvlggrfdlprppDTEA---LRTDAAGP-ARmtnaavnaviqmlpDRL--PTTADLADLW----------RLG 478  Frankia ...
jgi:Franean1_2668  437 VFAAAL--------------DRQRlwwTRDELAGAlLDvdldgipcvpralpRRNadP------KRWawgi--gpveRIG 494  Frankia ...
Q7NJB7             448 FID-----------------ERESlprREEHFRLAsVQvrdldve-yalrkhRFIlqVVCWDLDQGEdlpa--ahynRLG 507  Gloeobac...
WP_011748895       413 IVAGLA--------------GHQP------------DSdvalylrqilrawrDDGfsAYHAEGRETen--------aFLS 458  Paracocc...
Q01WF4             464 TIGAAL--------------DLDE------------SSdeihalyfvlrawvQARfqQESANPKKTes--------rFLL 509  Candidat...
jgi:Cpha266_1052   562 VITRAA--------------EISD------------ESdlslavrrlveawrKSRyqPYRNHTDEGDdpekkeletvYLS 615  Chlorobi...
CAM00375           437 Rrmaa-hatPRVfDDVRGLL----------SGVQEcigwardiERWSAAPAGIG--RCKSALYRLRVFAEVLEgh----- 498  Saccharo...
WP_020464646       483 R--------PAV-DAAKGIL----------ISMIN--------EAYVLSTDPDD--RVALATLAREVHAAVVA------- 526  Frankia ...
Q0RUJ2             533 Q--------PAL-DGVRGIL----------VSMIN--------EGYVLCPEPVE--RARLAQLAAAVHDAALAasggspp 583  Frankia ...
Q2JGZ6             479 R--------PAL-DAAKGLL----------INMIN--------EGYVLSPEPAD--RIRLARLAAAVHGASHAtirnt-- 527  Frankia ...
jgi:Franean1_2668  495 V--------LAV-DLFK--------------------------RAMWLAPPADHalRGRLRGYRGQLHGELATlrairrd 539  Frankia ...
Q7NJB7             508 RlaqilsrqIELlEIIKASL----------IAALSraeiasefLKLVEQDVPISqeRERV---RLQLYAYLLAv------ 568  Gloeobac...
WP_011748895       459 Rydld-frlRRL-IHLRAHIdeal----------------drrERIQGEKVALHlpPELLAPLRDRIEEELADlrrlasp 520  Paracocc...
Q01WF4             510 Qfdls-yreRRL-YFLLSRLdalyaggekaRSIANstgildrlEKLN----------------HEELKSAIRGlrg---- 567  Candidat...
jgi:Cpha266_1052   616 Nydia-frlRRL-DYFRKLLqk-------aIVNNNaediifreHALSVPE------RDAINTFYETVCKTLEGvyn---- 676  Chlorobi...
CAM00375           499 --------------------adRYWLNGARLEPIVESdeldGWIDR-------VlrrRERLqhhlpspvRP--------- 542  Saccharo...
WP_020464646       527 ----------------------PREQAGAHLLPLPSTpanrGGFTV-------V---RHTL--------RD--------- 557  Frankia ...
Q0RUJ2             584 sptgpgrgeggaaasriadargPASLYTSSPRP--------GVFTT-------V---SETL--------AA--------- 628  Frankia ...
Q2JGZ6             528 -----------------dttdtTATTATAALRP--------GVFTT-------V---SETL--------GA--------- 555  Frankia ...
jgi:Franean1_2668  540 dd-----------dfwrswsarPPAQPGADEDPRDSAdagdGSDPVepaapggSaerRARLrtwlqdalAS--------- 599  Frankia ...
Q7NJB7             569 --------------------------------------------------------hRAFF------------------- 573  Gloeobac...
WP_011748895       521 dssqaqtllagteigrldglisAEYSAVMKLATLDQR----------------YgkaREIYrstdikalVDk-------- 576  Paracocc...
Q01WF4             568 -------------------nrqSEASPDARPCPVHKDkcpiHGRGLvpvlgflRrerNELRrrgelnplAKvgpdregwk 628  Candidat...
jgi:Cpha266_1052   677 -------------------------------------------------------lrDFLIregkenpaAS--------- 692  Chlorobi...
CAM00375           543 ------L----------------L-----------GSVLASVeggegfqheLTGFARELLSIveSSGADAvpd------- 582  Saccharo...
WP_020464646       558 ------L----------------A-----------GASSAAV---------VAEATRRWLRG--AGDEET---------- 583  Frankia ...
Q0RUJ2             629 ------M----------------P-----------GAPLLDV---------LEEATRRWLRSdpAGTADAaeaagpsgpa 666  Frankia ...
Q2JGZ6             556 ------M----------------A-----------GAPLLDV---------IAEAARRWLRTdpEGDA------------ 581  Frankia ...
jgi:Franean1_2668  600 ------W----------------P-----------LPPGAADiprdtlpvrLGTVAERIVRLliDAADDLwr-------- 638  Frankia ...
Q7NJB7             574 -----------------------L-----------NQPGAQPdpaagyferLIDAATEAARAyiDGGDEQivwps----- 614  Gloeobac...
WP_011748895       577 --------------------------------------------------aLAKLGRDMRAAfdASSARI---------- 596  Paracocc...
Q01WF4             629 kwlgglLegtdeecakkgealfrL-----------GSPRP-------------DLRRQLLEMldAVNWAM---------- 674  Candidat...
jgi:Cpha266_1052   693 ------MvnewkscfkkgspgikTflndvlltcdcSAPLPAFdlkkdpcdaTSDKTDEFRQLldNAGIRAginp------ 760  Chlorobi...
CAM00375           583 ------------dagGVDAVAEATAVLHGIADRla--------------------------------------------- 605  Saccharo...
WP_020464646       584 ---------------SRTDLTLAWSTLGSVTENlrglltgvlarsapsrtattdladrpghgdgehggrhgrdgqdedrp 648  Frankia ...
Q0RUJ2             667 ghggpaghggpadpgGSAQPGSGWASLAPVVAElrgeiaalv-------------------------------rrwtpht 715  Frankia ...
Q2JGZ6             582 ---------------GQDELTRAWRSLERMIETlrteltdlv-------------------------------drrspaa 615  Frankia ...
jgi:Franean1_2668  639 --------------lGAPDAGDAVATVPHVAVEtdllkkllra------------------------------llsddlr 674  Frankia ...
Q7NJB7             615 ----------prtlaGIYDALKA--------------------------------------------------------- 627  Gloeobac...
WP_011748895           --------------------------------------------------------------------------------      Paracocc...
Q01WF4                 --------------------------------------------------------------------------------      Candidat...
jgi:Cpha266_1052   761 ------------dfaGLPDMMNKLMTCIHTAVM----------------------------------------------- 781  Chlorobi...
CAM00375           606 -aAAg-----eRVHldePEQLGYSLLEEAGARALRPLvvltapldVGRTPGTRINLLRVV------------------SD 661  Saccharo...
WP_020464646       649 fgPAaliapgpRTH---ANGLSLTARRRVAARTLRDF--------VGYLPTRRSRAALAL------------------LD 699  Frankia ...
Q0RUJ2             716 ppPAg-----sRIQ---PAGLSVGQRRALAARTLTDF--------VHYLPTTGADALIAL------------------LD 761  Frankia ...
Q2JGZ6             616 rpPAg-----pETR---PEGLSVGQRRAVAARTLADF--------VGYLPSTPADALIAV------------------LD 661  Frankia ...
jgi:Franean1_2668  675 ssPA-------------------ALRRRLLAVEVCQLamagaprdA---------------------------------- 701  Frankia ...
Q7NJB7             628 -----------KSNgidPFGLAFGVLSQVPDPDWADLrpvdlkdsILHIVEVASARLIGLsgleesprylqlfheyrhLD 696  Gloeobac...
WP_011748895       597 -------------------------RADLAAPELKPLldvyd--------------------------------dfhwHD 619  Paracocc...
Q01WF4             675 ------------KDtfvCAAWHVDQLLGMAAP-LPADananaaqvLRYCLRRQYD-AYDF------------------YD 722  Candidat...
jgi:Cpha266_1052   782 --TGkelegntEKDpsiTGTIEARKNINIALDRLSAVnneiaahlLFI-----YDYGYDL------------------HD 836  Chlorobi...
CAM00375           662 ----EQS-------SLPFEALRRGADIPLRI-------------ADKIRGADLSNFGAFLSARWRANDWMWGRMDAAASL 717  Saccharo...
WP_020464646       700 lhlvTHAltggdvvDQPVELVQVSADIRCGLdpsr------asaDRKLTGLQLGNFGAFAKSSWRASDWMWGRLDGAAWL 773  Frankia ...
Q0RUJ2             762 lhlvERAttg-vvlDQPVELVQISADLPTALdptr------rlaEDKVTGLQLGNFGAFAKSSWRANDWMWGRLDGAGWL 834  Frankia ...
Q2JGZ6             662 vhlvERStga-avlDQPVELVQISADLPNRLdpar------alaEEKVTGLQLGNFGAFAKSSWRANDWMWGRLDGAGWL 734  Frankia ...
jgi:Franean1_2668  702 --------------EQEVIFQQISGFTPNSFggp--------atPDKIAGIRLFWFGGFLKRSWRVNDWIWGRLDGATRM 759  Frankia ...
Q7NJB7             697 eellPYEyladfqeKEPIELVRISPHDAKMGyser------rdwKDKLAGDALYAFGGFFKRSWRSNDILWGRLDGLNRI 770  Gloeobac...
WP_011748895       620 vmtyPFLegselqeHSQVEVFRVSPADS-GLnp----------rPDKLAGIAVGAFGGFLNRDWREHDILWGRLDGAERI 688  Paracocc...
Q01WF4             723 avsfPILygtetatLKPTAVHRISPRDATSLideae----dsknRTKLAGDSLSAFGAFFQKRWRKNDLMWGRLDGAERI 798  Candidat...
jgi:Cpha266_1052   837 ittfPLFsggeygeGSNIGIYRISPLDATSLspeyslnknnggeSSKLAGTALGAFGAFLDRNWRRNDIMWGRLDGAERI 916  Chlorobi...
CAM00375           718 VGLLTD-------PRRLA-QRNAHLGAGG---------------------------LREALRA------IVSDPAPQELg 756  Saccharo...
WP_020464646       774 ARILLD-------PRRLVhLRDAAAPGAEppdsta----------------twlteFVELLAT------VAAGPVTADV- 823  Frankia ...
Q0RUJ2             835 VRILLD-------PRRLVlRRDLAVPPGPpadpgggagegrlagtatlarrgwlvaLVDDLAE------VAGTPVPQDA- 900  Frankia ...
Q2JGZ6             735 VRIMLD-------PRRLViRRDTAVPAGHahaaala-------------rrgwlvdLVDDLTE------VAGIPAPREV- 787  Frankia ...
jgi:Franean1_2668  760 VQAVLD-------PARL---RQLGRSAQE---------------------------THDALHR------IAVGGAYRDD- 795  Frankia ...
Q7NJB7             771 VQALVTres--lsHFRQFlKRQTDPRLQRwaaspe----------------hhkgdLRHYLAQelvdgaFAQSPEAERKq 832  Gloeobac...
WP_011748895       689 VAALMSdr---peAERAAwTQEIQNQI-----------------------------LREEYGE--------AAGQARRLa 728  Paracocc...
Q01WF4             799 IGMLLPgtdeptkKLRAElLREAQGAI-----------------------------LAECLHA----------------- 832  Candidat...
jgi:Cpha266_1052   917 ITALLPnhe--nqEARQNfIDKAHRAI-----------------------------ITDTLNTwlpelkRIQVPSHRELh 965  Chlorobi...
CAM00375           757 dL--------DEEraaqwrgflaelwsahadevraeldALFADPDdehalkqtrkllierlhwtivacelpfvatvkpga 828  Saccharo...
WP_020464646       824 -L--------DEL-------------------------AWLDDPD----------------------------------- 834  Frankia ...
Q0RUJ2             901 -L--------DEL-------------------------AFLTDPD----------------------------------- 911  Frankia ...
Q2JGZ6             788 -L--------DEL-------------------------GFLTDPD----------------------------------- 798  Frankia ...
jgi:Franean1_2668  796 -LsgyfrdarDEIfa---------------------elAFLDSED----------------------------------- 818  Frankia ...
Q7NJB7             833 lL--------DSLvala------------------esqNGLADFDledfqkrlvlmghreilgtd----frrvlddaiae 882  Gloeobac...
WP_011748895       729 lLkaklrdarIDEdafeetaaqalgvkdaaeldlrrfgAHYKDLK----------------------------------- 773  Paracocc...
Q01WF4             833 ----------DDVrnlltavagsvvgakkedtesslarQALEGPGreerirafvepdalvdy-----------vresyai 891  Candidat...
jgi:Cpha266_1052   966 lIsiletignslag------------kddwkhvfktyyTIDHEPE----------------------------------- 998  Chlorobi...
CAM00375           829 dtdgggepaTPPPPELTDQ------------------------------------------------------------- 847  Saccharo...
WP_020464646       835 ---------AAVPAALPET------------------------------------------------------------- 844  Frankia ...
Q0RUJ2             912 ---------APVPPSLPVT------------------------------------------------------------- 921  Frankia ...
Q2JGZ6             799 ---------APVPPNLPVT------------------------------------------------------------- 808  Frankia ...
jgi:Franean1_2668  819 ----------PGAQAGSLT------------------------------------------------------------- 827  Frankia ...
Q7NJB7             883 qldwnaqklKPTRPQTPPT------------------------------------------------------------- 901  Gloeobac...
WP_011748895       774 ----------PVGPRPPEI------------------------------------------------------------- 782  Paracocc...
Q01WF4             892 dktyqpewtLPVAARVARVtgelleflaaerkwnagpivwvvrltrlfwgmvevaipqslsfatfryllgiywfaggliv 971  Candidat...
jgi:Cpha266_1052   999 -----------AAPNLKRV------------------------------------------------------------- 1006 Chlorobi...
CAM00375           848 -------------VRRYRVGRERlpDLGEKRIAALA 870  Saccharopolyspora erythraea NRRL 2338
WP_020464646       845 -------------AAWVATGIQR--EIAAGELTSVA 865  Frankia sp. EAN1pec
Q0RUJ2             922 -------------ATWVAAGLQR--DIAAKELVGLA 942  Frankia alni ACN14a
Q2JGZ6             809 -------------ATWVAAGIQR--DIAAKELVGVA 829  Frankia casuarinae
jgi:Franean1_2668  828 -------------ATTRAVTRRLhaDILAEEMPHLV 850  Frankia sp. EAN1pec
Q7NJB7             902 --------------------FEPatGYFDRTVSALA 917  Gloeobacter violaceus
WP_011748895       783 -------------AGWGSRGMA----ILSRMIDDLp 801  Paracoccus denitrificans
Q01WF4             972 ltglllgqaaltgAGWKMLGAGVavWLVVQMLHEAM 1007 Candidatus Solibacter usitatus Ellin6076
jgi:Cpha266_1052  1007 ---------------------GRssAIVSQMINGVN 1021 Chlorobium phaeobacteroides DSM 266
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