Conserved Protein Domain Family
Tom37_C

?
pfam11801: Tom37_C 
Tom37 C-terminal domain
The TOM37 protein is one of the outer membrane proteins that make up the TOM complex for guiding cytosolic mitochondrial beta-barrel proteins from the cytosol across the outer mitochondrial membrane into the intra-membrane space. In conjunction with TOM70 it guides peptides without an MTS into TOM40, the protein that forms the passage through the outer membrane. It has homology with Metaxin-1, also part of the outer mitochondrial membrane beta-barrel protein transport complex.
Statistics
?
PSSM-Id: 371732
View PSSM: pfam11801
Aligned: 20 rows
Threshold Bit Score: 133.964
Threshold Setting Gi: 74694230
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
CCK73448     185 EMEGFenihidekHEHDPSMAH-SKTFKLTKYKKMQNKKTLQNLQDDMNYNKRFVEVLNDWFEVAKDvpsIyDGEGSCSS 263 Naumovozyma dai...
CAR21542     152 EQVEQp-------NAELDGLVQ-SKAFKLTNASKARGEELLKSARYNLQYMSRLNRHVVSWREARAR---L--DKDSTAA 218 Lachancea therm...
Q6CII7       156 EENEStsnhqdelSEKATELAQ-SKVFKITRDSKRQQTKKLQELKNNSRFTTKLDNVLTNWESARQS---L--ASAVLPA 229 Kluyveromyces l...
BAO41474     162 DLDSGakgsqnshQDKAIEMAQ-SQVFKVARDNKKQQKKRLQDLKNNSRVISNLTQILTHWTTARPA---V--DAKLIPA 235 Kluyveromyces m...
XP_003645726 177 ESSDDanignsitDQAEKELARsSKAFRNIEKQHEKNQQTLNYVKYSMQYMSKLDSSLTPWIEARKE---IgKELNVL-- 251 Eremothecium cy...
Q759Y7       133 RARAQrggtpapaHDAEKELAQhSKTLQATRELRERGEKALADAAAEMEYAAALDRALQPWIAVRGA------AATLGPA 206 Eremothecium go...
EDN64449     183 EFVESk------aMESASQLAQ-SKTFKIAHKNKIKGKQELQQVKYNLQFDNRLQSCVSNWLAARKK---L-DDSVILSS 251 Saccharomyces c...
EJS42408     183 EFEESk------aLESASQLAQ-SKTFKIAHENNIKNKQDLQQVKFDLQFDNRLQKCIKSWLDVRKK---L-DQPVIVSC 251 Saccharomyces a...
EJT42708     179 DFVESk------aLESASQLAQ-SKTFKITHENNVKNKQDLQQVKYNLQFDNRLKTCIKHCLQVRKK---L-DESVVLPP 247 Saccharomyces k...
XP_003954609 154 EESDKq------eDIEEEDLTQ-SKTFKLQKVKRKAQKEQLTDLKNNLKFRERSSSLLKEWKEMRYSealLsDRSRKIPA 226 Kazachstania af...
CCK73448     264 ptYLLLLANLYIQMELPNGSKIKEYL---SSVEHWDKISNDLEYLKtsgygemiiqkdgSIDRngGLQ-LQPAKFNEQGN 339 Naumovozyma dai...
CAR21542     219 --DFLLWANLFVQMELPDGQLVKEQLqtaLGPEDYESIIKRLNDCS-------------KSTS--TLE-LRGPFFAEKGN 280 Lachancea therm...
Q6CII7       230 --DLVLVAHLKVQMALPQGDLLRSHL-----RNQYPSLYDKVNELI-------------EKYDnsPVP-NRDPTFSESGN 288 Kluyveromyces l...
BAO41474     236 --DLLLAAHLKVQMDLPQGDIVNTHL-----LNNFPTLYSTVKEIQ-------------QRNSdlQIPnIRDPSFTESGN 295 Kluyveromyces m...
XP_003645726 252 --DILLYAHIYVQMILPDGARIKEHLk-kTFPEFFTMLMSTCDICS-------------SRKAd-KVT-IRDPTFLESGN 313 Eremothecium cy...
Q759Y7       207 --ELLFAAHLYVQQQLPDGARVTAHLr-aHYPALCDGLLRACELHA-------------CAPRaaAVA-VRAPTAAETPS 269 Eremothecium go...
EDN64449     252 --DLLFLANLYVQLGLPDGNRIRSKLeqtFGSELLNSMSNKIDDFV-------------HRPSn-NLE-QRDPQFREQGN 314 Saccharomyces c...
EJS42408     252 --DTLFYANLYIQLNLPGGNRIRSKLeqtFGGEFVNNTSNKIDKLV-------------QGSAd-NLE-QRDARFKEQGN 314 Saccharomyces a...
EJT42708     248 --DILFYANIYVQLSLPDGNRVRSKLeqtFGGEFVNNTLNKIGEFV-------------QSSDn-DLE-QRDPRFKEQGN 310 Saccharomyces k...
XP_003954609 227 --DYLLYANLYIQLNLPDGKQIREAMklkLESSFCNKIESELNHYN-------------KLADenSLK-FRAPTFAEQSN 290 Kazachstania af...
CCK73448     340 IITSLYNYITWY 351 Naumovozyma dairenensis CBS 421
CAR21542     281 VVMSAYHALQRL 292 Lachancea thermotolerans CBS 6340
Q6CII7       289 VVTSTCYFLRTF 300 Kluyveromyces lactis
BAO41474     296 VVMSTFNLIKTY 307 Kluyveromyces marxianus DMKU3-1042
XP_003645726 314 IPMTVYRSITSF 325 Eremothecium cymbalariae DBVPG#7215
Q759Y7       270 VPRELYRYVTSY 281 Eremothecium gossypii
EDN64449     315 VVMSLYNLACKY 326 Saccharomyces cerevisiae YJM789
EJS42408     315 VVMTLYNLACKY 326 Saccharomyces arboricola H-6
EJT42708     311 VVMSLYNLACKY 322 Saccharomyces kudriavzevii IFO 1802
XP_003954609 291 VATSLYYLAKMY 302 Kazachstania africana CBS 2517
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap