Conserved Protein Domain Family
SID
?
pfam11778: SID 
Septation initiation
This family is required for activation of the spg1 GTPase signalling cascade which leads to the initiation of septation and the subsequent termination of mitosis. It may act as a scaffold at the spindle pole body to which other components of the spg1 signalling cascade attach in pombe. In S.cerevisiae it is both required for the proper formation of the spindle pole body outer plaque and may also connect the outer plaque to the central plaque embedded in the nuclear envelope.
Links
?
Statistics
?
PSSM-Id: 403090
Aligned: 20 rows
Threshold Bit Score: 146.969
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
XP_003957747  432 LKFLEGDFSKRITFETIHQKNPEkFTKEIYDYLEFPTIDNMNLIELQNIIKHFSLFFEVPLSKFFKKLPTICIYLRYERN 511 
XP_003670940  394 IRDIQGDAAERIKYDRYQLMKLG-ITEDLFKTYGIDEVEILDKISLENIVKRTMVLLNIPFNELNTKISRIAVFLRYEKP 472 
XP_003677377  351 LELLEGDKENMVVFDKETLTRFG-VNGDIAKYLSLTQVNSVDRITLINTVKRIMIFLQMSYTDLPDKIQRLAVYLQYEKP 429 
CCH61969      875 LEKLTGDKSLRITENNIRNTFKGdGSNSLIENLKLDQVDELTMIQLQNALKNIIVSLKIPFDKFSYKMPLITIYIHLERV 954 
XP_003675959  465 LKKKMGDATEMITFSNTCKVRLD-ITKDMYERLMVDDVEKMNLVELQNIIKNLILLFEIPLNKLTKRLPLMVIVFMYEKP 543 
CCF56228      394 LNKLRGDSSELLTFKDFKNSD---IDKRLYQALQVDKVEQLDLVQLQNKMKKVIVDMQTPLDKLDAKLPLANLLIKSELV 470 
Q6FP18        394 LLSITGNTNNMLSFEKLKQLDNS-FCKEEYVSLKISEIEDISLVQLQNMAKMICMYFRTPFDKLDIKLPLAAIQIIHERK 472  [Candida] gla...
Q6FWH7        482 LQNLEGNIEESLTEEALKVRFIS-LSSENYNTLDVECIDRQDLVSLRNLLKVLTLTLEIPFSKLQTTIPLLAIRLYHENT 560  [Candida] gla...
CCK70756      397 LNRVVGDAANKIRYASLKHVH---MTKEKYDELAIDSVEQYTLTELQNIVKRASLELEVPPSTLLVNLPRLNVAIE-QQV 472 
Q6CQ58        615 YEKVKGNAADKITPDTLMKIHTH-MNKESYENLELDTIDNLNLVECQNTIKNIVAILDISYSKLSSKLPLVNIMLRYEKT 693  Kluyveromyces...

XP_003957747  512 LLHFFVDRLNYQIYNpsKKINFKSYTVDAYQQYLKNgNSFEDINHPLQKCLDDLYNEI 569 
XP_003670940  473 LLRKFVTELHMATFG--TSADLIYKANRATKQFNTT-GDLTHIDHPLNRCLDKLLNQL 527 
XP_003677377  430 LLRKFVNELHRMVFG--EPIDLVNKAAVAYSQFSKT-GDMNSINHPLEKCLNNLIDHV 484 
CCH61969      955 IFLKFINRIHFKLHD--RYFEMERFTTEAYVQFMNT-HDLNTVKHPIATYLHSMLKEL 1009
XP_003675959  544 LFSYFVNRLFYQIKN--EQLDLKHFTDDTYRQYLEG-NSIKNLNHPLKDVLEELFQYI 598 
CCF56228      471 ITLDFINRLYQTMYN--EGLDFNHYTEEAYLQYRKS-NYLDPWQHPIRPIIDHLYNDI 525 
Q6FP18        473 ILIHFANILNEYFMS--KPLSMKKCTDSAYCEWQLS-HNIFRIEHPLKFKLEELYTTI 527  [Candida] glabrata
Q6FWH7        561 SLLSFCNTLHMHLYG--KPLAIKNYRRWAYADYLKT-CNIHEVQHPIKPILEAMFNKI 615  [Candida] glabrata
CCK70756      473 ILMKFAYWTLQVFAN--QELDVLSFTERAVEVYETT-GCMTDALRPLEQTMQGLrtll 527 
Q6CQ58        694 MLFHFANKVHNLLFH--QEIDFKTFTKKALENYWTH-RNAKEIQHPLEQCLKDLYKSV 748  Kluyveromyces lactis
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap