Conserved Protein Domain Family
SET_assoc

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pfam11767: SET_assoc 
Histone lysine methyltransferase SET associated
SET domains are protein lysine methyltransferase enzymes. SET domains appear to be protein-protein interaction domains. A subset of SET domains have been called PR domains. The SET domain consists of two regions known as N-SET and SET-C. SET-C forms an unusual and conserved knot-like structure of probably functional importance. Additionally to SET-N and SET-C, an insert region (SET-I) and flanking regions of high structural variability form part of the overall structure. This domain is found in fungi associated with SET and N-SET domains.
Statistics
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PSSM-Id: 403081
View PSSM: pfam11767
Aligned: 61 rows
Threshold Bit Score: 65.6166
Threshold Setting Gi: 501304225
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003715029  472 FVAHKSVPVSPLTVPHMKKRLRGFTMDDILiIEKYGYYLIFADSSygrdQAERCYKCTNHSRFFDYDMIM 541  Pyricularia oryzae 70-15
Q6CEK8        552 FIAGKYLPSEKVFASDIRRILRDFGWFDVL-KEGDGFYVFFDNNR----DTVECYEAMNGRKVNGHQMAM 616  Yarrowia lipolytica CLI...
CBQ73061      768 FVFIPRPKNCDVALEDVQSQLRSTEPIWVK-EGDDGFYAAFNNNQ----EASKCKIVNETLSIGGYTLQV 832  Sporisorium reilianum SRZ2
Q4PB36        780 YVHIPRPKNCDIDVTSVEAQLRSTAPIWVR-EGQKGFYAAFHTSK----EANQCKVVNETLTIGGYTLQV 844  Ustilago maydis 521
XP_007874671  334 FINEKCLPFSKFSINDLKKHLNKHDWTDIC-IDKKGFYIIFKDNQ----SAQKCFVTMNQTSIYQYRITM 398  Pneumocystis murina B123
Q9Y7R4        278 lIDDRFVPPDRVYYTDIKHHFRKFLYEKIY-MNKDGFYITFNNYR----EASNCYRALDRTYVQNCRIKL 342  Schizosaccharomyces pom...
XP_002172037  298 FIDDRFVPPDRVLYSDIRHHFRKYYYDRIY-MDRRGFYITFSNYE----EARECYYRLDRTYVNDCRIKL 362  Schizosaccharomyces jap...
CCG80850      268 FIPGKVLPLHKVTAQELQIHFSGKRTEDIF-TDPYGFYVLFENDE----VATRAHKIMDKSTFLGYRLYM 332  Taphrina deformans PYCC...
EOR04869      728 FIDKSSLPVHSVDVVDVRAFFGQFKVSDVL-KNDDGWFVLFTKPG----IAGRAMTTSDGKQCSGFTMHL 792  Wallemia ichthyophaga E...
EKC97692      719 FIDIKSLPYGQVRDEHVQNHFRAFKPDAVL-HNHTGWYILFGDDQ----TAHRA-KLMDKTAILSHRINV 782  Trichosporon asahii var...
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