6V4X


Conserved Protein Domain Family
CPSF73-100_C

?
pfam11718: CPSF73-100_C 
Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term
This is the C-terminal conserved region of the pre-mRNA 3'-end-processing of the polyadenylation factor CPSF-73/CPSF-100 proteins. The exact function of this domain is not known.
Statistics
?
PSSM-Id: 403042
View PSSM: pfam11718
Aligned: 147 rows
Threshold Bit Score: 105.279
Threshold Setting Gi: 134061616
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
6V4X_H       479 QRVSGI-LVK--RNFNYHILSPCDLSNYTDLAMSTVKQTQAIPY--T-GPFNLLC-----YQLQKLTGDVE--------- 538
CAM38647     491 EFVSGVmLVS--GQHQYSIVHPDDVPVFTDLSVNRVQQAMVLPLprHrSPLEVLQvlqryFAQSKLFEDVAprqsteqea 568 Leishmania braz...
XP_003531594 482 ETVSGL-LVK--KGFTYQIMAPDDLHVFSQLSTTNITQRITVPY--S-GAFSFIQ-----HRLKRIYESVEq-------- 542 soybean
XP_010658078 488 ETVSGL-LVK--KGFTYQIMAPDDLHVFSQLSTANVTQRITIPY--T-GAFGVIK-----HRLKQIYESVEs-------- 548 wine grape
XP_002508805 494 DRVSGL-LVQ--KDFGHMIIAPEDLHEYTSLKTAKLTQRQKVPT--T-QKLGELR-----FALEALFEGIH--------- 553 Micromonas commoda
XP_002948028 493 GVVRGV-LVRqaGGFGQQLLHPDDLPRYTKLLKGRVTQRQAISV--D-VPFSVIR-----LALEVMFEGVEgagtv---- 559 Volvox carteri ...
EEY53455     484 TIISGL-LVE--VDSQTHLMDKEDLSTYTKLISGTITQKQHVPF--EyNSFDVLI-----TFIRQMYEDVV--------- 544 Phytophthora in...
EFA80253     379 KKIAGL-LVT--KDFTHHIIAPSDLHNYTNLKINTIKQKQTVPF--A-QKYLLLS-----STLEQLYDEME--------- 438 Heterostelium a...
EGG16071     494 TSVQGL-LVI--KDFTHTIMAPGDLQNFTNLKTNIIKQKMTIPF--A-QNYLLLK-----STIQQLYDDVKeqe------ 556 Cavenderia fasc...
Q86A79       501 DIIQGI-LVT--KDFTHHILSASDIHNYTNLKTNIIKQKLTLPF--A-QTYHILI-----STLEQIYEQIIest------ 563 Dictyostelium d...
6V4X_H       539 ---------ELEIQEK-PALKVF--KNITVIQE-PGMV--------VLEWLANPSNDMYADTVTTVILEVQSNPKIRK-- 595
CAM38647     569 teaqqaaaeRGETRDLdTTLLFVs-KDVTVDVH-KSSQaqt---tlTITWYSSHYNDLLADVTCIALAKLAEEPHEAE-- 641 Leishmania braz...
XP_003531594 543 ---------SVDEESGvPELQVH--ECVTVKHEaEKHI--------SLHWTSDPISDMVSDSIVALILNINRDVPKIMa- 602 soybean
XP_010658078 549 ---------LPDEESEvPAFRVH--ERVTVKHEsEKHI--------SLHWTSDPISDMVSDSIVALVLNISREIPKVVv- 608 wine grape
XP_002508805 554 -----------TGSPEpPGLSVNg-GQLTILKRpADKKwga--ehaLLQWDADPINDMIADAVLSVILQLEEEPEHLTra 619 Micromonas commoda
XP_002948028 560 ----svtsvPGAAGKGkEVLAVMvgDTVEVRYI-PADDttgmvahvVLEWEGGRHGDMVADAVIAVVLQAVGEPVGASna 634 Volvox carteri ...
EEY53455     545 ------------HLEKeNRVAVC--KQVVVTRCaVAKGate---klVVEWTSAPTADMIADSLIALAMHAQASPASFKls 607 Phytophthora in...
EFA80253     439 ---------ESKTKDDkPTIKIY--GSILITYNvGSHV--------TIEWDSNPVTDMVADSIVALIMQIESNPFSLRvk 499 Heterostelium a...
EGG16071     557 -------siNNNNNNNnPILKIY--NSIIITLFaPTHV--------IIEWESNPVNDMISDSVIALISQIETNPFSLRvg 619 Cavenderia fasc...
Q86A79       564 -------esTGGGGNEkPTITIY--NEIKLIYNiGVSI--------ILEWNSNTVNDMICDSIIALISQIELNPLSIKvr 626 Dictyostelium d...
6V4X_H       596 -----------------------------------------------GAVQKVSKKLEMHVYSKRLEIM--LQDIF---- 622
CAM38647     642 -----------------------------------------------GEDVLVPADVSGQDRIFRVKCFhsMISQFyssv 674 Leishmania braz...
XP_003531594 603 -----------------------------------------------ESDVIKIEEENKKKAEKVMHAL--LVSLF---- 629 soybean
XP_010658078 609 -----------------------------------------------ESEAIKTEEENGKKAEKVIHAL--LVSLF---- 635 wine grape
XP_002508805 620 ea------------------------------------------ahkDAMKNKDKAGVQAARLRIVAAM--LGVQF---- 651 Micromonas commoda
XP_002948028 635 es------------------------------------------amnRARAAGDETAAAAAELQLIAAL--LRSQY---- 666 Volvox carteri ...
EEY53455     608 nqptaacphdhskkt----------------ntedeangkkdttdleKAARELGGADQDALNLLIVFRL--LKDQY---- 665 Phytophthora in...
EFA80253     500 sskenngdiiltdeqsss----------sgiplvkmekeneqdeedlTIMTKSRKKSQQLTLRTEIMTM--LSKQF---- 563 Heterostelium a...
EGG16071     620 emnnnnnnnnnngdtepinngngqtikvkkeksddqeeeeedeeqdvMIMTKSRKQSQKIEMITEVKSL--LEHQF---- 693 Cavenderia fasc...
Q86A79       627 npnfnnidekeeitkddiek-----ekekekeqqdgddddddeiqikVVSRKSRKLSNKLNTITEVKLL--LEQQY---- 695 Dictyostelium d...
6V4X_H       623 ------GEDC-VS----VKD--DSILS-VTV-DGKTANLNLETRTVEC------EegsedDESLRE---------MVELA 672
CAM38647     675 ktnlssGSCS------------------VTLaDGQVANI------VDCievyleS-----STGKKDvdydapevqKLKQI 725 Leishmania braz...
XP_003531594 630 ------GDVK-AGengkL------I---INI-DGNVAVLNKESGEVES------E-----NEGLKE---------RVRAA 672 soybean
XP_010658078 636 ------GDVK-LGengnL------V---ISV-DGNVAHLDKQSGNVES------E-----NEGLKE---------RVRVA 678 wine grape
XP_002508805 652 ------GEPRaIDeenqVV-----E---LRV-ENADVAVRYGNRDVDC------A-----DAAVKA---------RVETA 696 Micromonas commoda
XP_002948028 667 ------GPAV-VDeaggSI-----S---LSV-DGVSVLVDYRAGKVIC------G-----EVGLRA---------RIEKS 710 Volvox carteri ...
EEY53455     666 ------GDVD--------LDfeTNKIH-VRTpSGVDAVVDHASQEVEC------K-----DATLKL---------KLQTT 710 Phytophthora in...
EFA80253     564 ------SELK--------PDqdDPLLMhLHIdDDKSASIHLETLKVHS------N-----TPELKT---------QIEKA 609 Heterostelium a...
EGG16071     694 ------GPMQ--------PDsdNPLILlFNL-DDKNASIHLEDLTVEC------A-----DSELKQ---------YLENS 738 Cavenderia fasc...
Q86A79       696 ------GNFK--------VDenDPLILhFNL-DNQKAIIHLETLTVES------L-----DQILKQ---------KIENS 740 Dictyostelium d...
6V4X_H       673 AQRLYEALTP 682
CAM38647     726 LKRIYLTLFP 735 Leishmania braziliensis MHOM/BR/75/M2904
XP_003531594 673 FQRIQSSVKP 682 soybean
XP_010658078 679 FQRIQNAVKP 688 wine grape
XP_002508805 697 LGRIDMAIAD 706 Micromonas commoda
XP_002948028 711 LDRLATAIRP 720 Volvox carteri f. nagariensis
EEY53455     711 IQRIEGALKP 720 Phytophthora infestans T30-4
EFA80253     610 IRRISLAVHP 619 Heterostelium album PN500
EGG16071     739 INRIKLAVHP 748 Cavenderia fasciculata
Q86A79       741 IKRIILSVSP 750 Dictyostelium discoideum
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap