Conserved Protein Domain Family
Apis_Csd

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pfam11671: Apis_Csd 
Complementary sex determiner protein
This family of proteins represents the complementary sex determiner in the honeybee. In the honeybee, the mechanism of sex determination depends on the csd gene which produces an SR-type protein. Males are homozygous while females are homozygous for the csd gene. Heterozygosity generates an active protein which initiates female development.
Statistics
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PSSM-Id: 152107
Aligned: 5 rows
Threshold Bit Score: 115.204
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q2F424  33 TSHKHYSRSREREQKSHKNENSYRQYQETSRETSRDR--RERERECKIISSLSNNYNYKNyNNNYNNYNnkHYNKHynkh 110 giant honeybee
Q2F498  36 TSRKRYSRSREREQKSYKNENSYREYRETSRERSRNRkeRERSRERKIISSLSNNYNNYN-NNNYNNNN--NYNKHl--- 109 Asiatic honeybee
Q6Q095 267 TSRKRYSRSREREQKLYKNKREYRKYRETSKERSRNRteRERSKEPKIISNNNSLSNNYNyNNNYNNYNkhNYNKL---- 342 honey bee
Q2F462  35 TSRKRYSRSREREKKSYKNENSYREYRKTSRNR------RERSREH--------LSNNYNyRNSYNKNL----------- 89  Asiatic honeybee
Q6Q089 282 TSRRRYSRSREREQKSYKNEREYREYRETSRERSRDRrgRGRSREHRIIPS----------------------------- 332 honey bee
Q2F424 111 ynkhykqYYNINYIEQ--IPVPVYYGNFPSESIMVKPWVSMQEQVPRFRYIGPLTPF-PRLISPNMYRpRPPLNPRFRPM 187 giant honeybee
Q2F498 110 -------YYNINYIEQ--IPVPIYYGNFPPNPIMVRPWVPMQEQIPRFRYIGPLTSFpPRFIPPNTYR-RPPLNPRFRPM 179 Asiatic honeybee
Q6Q095 343 -------YYNINYIEQipIPVPVYCGNFPPRPM--GPWISMQEQIPRFRYIGPSTPF-PRFIPPNAYRfRPPLNPRFGPT 412 honey bee
Q2F462  90 -------FYNINYIQQ--FPIPIYYGNLPPRPI-VRLWVLMRGQVPGYRHIGP--SFpPQFITRNR---CPPPNPRFRPM 154 Asiatic honeybee
Q6Q089 333 -----------HYIEQ--IPAPVYYGNFPPRPIMVRPWVPMRGQVPGSRHIGPLTPFpPRFIPPDMYRlRPPPNPRFGPM 399 honey bee
Q2F424 188 Y 188 giant honeybee
Q2F498 180 Y 180 Asiatic honeybee
Q6Q095 413 H 413 honey bee
Q2F462 155 Y 155 Asiatic honeybee
Q6Q089 400 Y 400 honey bee
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