Conserved Protein Domain Family

pfam11636: Troponin-I_N 
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Troponin I residues 1-32
This family of proteins represents the cardiac N-extension of troponin I. This region of the protein (1-32) interacts with the N-lobe of cTnC and modulates myofilament calcium(2) sensitivity.
PSSM-Id: 371640
View PSSM: pfam11636
Aligned: 5 rows
Threshold Bit Score: 45.6293
Threshold Setting Gi: 1099182335
Created: 21-May-2020
Updated: 7-Aug-2020
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
Format: Row Display: Color Bits: Type Selection:
4Y99_C         1 MAD----------GSSDAareprpAPAPIRRRSS-NYRAYAT 31 
Q5PYI0         1 MAD----------QSGNA------APPPVRRRSSaNYRAYAT 26  horse
XP_018870234   1 MAD----------RSSDAareprpAPAPIRRRSS-NYRAYAT 31  western lowland gorilla
ELW64743       1 MAAwglgsdgaplPQPQAgdp-rpAPAPVRRRSSaNYRAYAT 41  Chinese tree shrew
XP_004866728   1 ----------madESSDAageprpAPAPVRRRSSaNYRAYAT 32  naked mole-rat
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