Conserved Protein Domain Family
Snurportin1

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pfam11538: Snurportin1 
Snurportin1
Snurportin1 is a novel nuclear import receptor which contains an N-terminal importin beta binding domain which is essential for its function of a snRNP-specific nuclear import receptor. Snurportin1 interacts with m3G-cap where it enhances the m3G-cap dependent nuclear import of U snRNPs in Xenopus laevis oocytes and digitonin-permeabilized HeLa cells.
Statistics
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PSSM-Id: 402920
View PSSM: pfam11538
Aligned: 17 rows
Threshold Bit Score: 40.3805
Threshold Setting Gi: 82080976
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_009029755  26 HPRLSVYKnYARHDPerSQEKRRKEIMK--TMKEKRSNVVERLRN 68  Helobdella robusta
O17066        26 HPRYSQYKnLTKAAE--QQAKRREETLE--RQKNGRFDTFMKLRN 66  Caenorhabditis elegans
XP_018651393  30 HPRLSLYKnKGRAA---DQEKRWRQKLSilKSKKERSDHFDHNRF 71  Schistosoma mansoni
XP_002601532  25 HPRLAQYK-AKSHDL--AQSERRRQMLD--RQKKQRQDVANLARR 64  Florida lancelet
KJE94202      22 HARQAQYK-AGRQPA--TQAERRKKLLD--RQKERRHELVDFARR 61  Capsaspora owczarzaki ATCC 30864
XP_002116445  26 HPRFAQYK--STTLP--DQHARRQKELE--RQKRKRSEAYNLLRh 64  Trichoplax adhaerens
XP_001623266  26 HPRIGNYKvKPHNVP--DQHVRRERKLE--QQKKKRMDFVNYSRK 66  starlet sea anemone
EGF79077      15 thRISQYK--FQPSL--SQDVRRQRALE--FQKKRRLQQVDAARK 53  Batrachochytrium dendrobatidis JAM81
EEC06944      25 HPRFASYK-VKYSAS--SQSERRREFIE--KQKQRRFDFQQHARN 64  black-legged tick
EFX74221      25 HPRFSQFK--KTSKT--SQEVRRRRTLE--NQKQSRYDYYNHCRc 63  common water flea
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