2OT8


Conserved Protein Domain Family
HnRNP_M

?
pfam11532: HnRNP_M 
Heterogeneous nuclear ribonucleoprotein M
HnRNP M is a splicing regulatory factor that binds to the auxiliary RNA cis-element ISE/ISS-2 which promotes splicing of exon IIIb and silencing of exon IIIC in the fibroblast growth factor receptor 2 (FGFR2). By binding to ISE/ISS-3, HnRNP M plays a role in the regulation of alternative splicing in FGFR2 as it induces exon skipping and promotes exon inclusion.
Statistics
?
PSSM-Id: 402915
View PSSM: pfam11532
Aligned: 5 rows
Threshold Bit Score: 28.4128
Threshold Setting Gi: 0
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
2OT8_C         2 RPAQNEKRKEKNIKRGGNRFEPYANPTKR 30 
1_pfamImport   1 GPTQKKKKREKNVKRGSNHFEPYANPTKR 29 
EDL10200      24 RPTQNEKRKEKNIKRGGNRFEPYSNPTKR 52  house mouse
XP_027328440  86 RPTQSEKRKEKSVKRGGNRFEPYANPARR 114 mallard
RMC01026      35 RPTPNEKKKEKGMKRGGNRFEPYANPAKR 63  Hirundo rustica rustica
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap