2K0S


Conserved Protein Domain Family
ARL2_Bind_BART

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pfam11527: ARL2_Bind_BART 
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The ARF-like 2 binding protein BART
BART binds specifically to ARL2.GTP with a high affinity however it does not bind to ARL2.GDP. It is thought that this specific interaction is due to BART being the first identified ARL2-specific effector. The function is not completely characterized. BART is predominantly cytosolic but can also be found to be associated with mitochondria. BART is also involved in binding to the adenine nucleotide transporter ANT1.
Statistics
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PSSM-Id: 402912
View PSSM: pfam11527
Aligned: 82 rows
Threshold Bit Score: 80.3005
Threshold Setting Gi: 123457881
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2K0S_A        16 DIVIGNIEDIIMEDEFQHLQQSFMEKYYLEFDDS-------EENKLSYTPIFNEYIEILEKHLEQqLVERIpGFNMDAFT 88  zebrafish
XP_002899562   5 GFLVDAVAEFVKGSVWRDTVTHFLETHYKRFLTDseseskvNGYTLEQYDSFMAFKDRVERMLEG-VVSDL-SCSGEDLV 82  Phytophthora in...
EAY14484       4 EELLKKISKYLASDEWWSPIFDFKTTNCVLFKEG-------ENASTQEYMCYKSFLHTITNLVDCqLCNKL-DISADEFE 75  Trichomonas vag...
XP_001320130   3 ERTIIQICNFFTSEAWWKPVCGFLATNCMQFE-S-------PENTVEQYNLFNQFQSLVQDLFDSfLCKTV-NMRPSALE 73  Trichomonas vag...
XP_001316501   5 EFILAKTAEFISSEDWWGPIIKFMYKNADKFKT--------DGYTAEKYQIFLQFSEIVCNLFDNsVSKYA-HISDNSLE 75  Trichomonas vag...
XP_001304740   5 DFILSSMLEFLASDSWWSNILDFMLSKCEPFQKH-------DTISIKEFIVYQEYLSFLERLLYNdFCNQF-SLEPRELE 76  Trichomonas vag...
EAY01939       5 NTIYDSIIDFLSGEMWWGQLLDFMLAHCECFKPR-------DYSTVEEFNIYKDYCVFLEQIVEKqLCQNV-KLTTKQFE 76  Trichomonas vag...
EAY12401       4 EEFIDFVADFLSSDDWVVPTIDFMMSNCSSFNES-------SYNSLEEYKIYLQYTDLLENIITNtLCTDI-GVSFEEFQ 75  Trichomonas vag...
XP_002901151   7 DPVVRALAEYIKTPQFQCQFEQFFLDHALTFTDA-------LEHQLAYMTIYVEFQHMFNEHMKI-FLTQQ-GVTEDEFA 77  Phytophthora in...
KAE8878721     5 GFLVDAVAQFVQGSEWRDAVTHFLESHYKRFLTDaqpqgkvAEYTLEQFDSFMAFKDRVERMLEK-VVSDL-GCSGLDLV 82  Phytophthora fr...
2K0S_A        89 HSL-----KqHKdEVSGDIL--DMLLTFTDFMAFKEMFTDYRAEK 126 zebrafish
XP_002899562  83 EAVkenlkYeSA-LSTEKRFciQTLLTFDDYDAFYSRIREYATEK 126 Phytophthora infestans T30-4
EAY14484      76 ELIyn-syKqKN-ATAKLIV--RTLQNILDFTQFREEMIKENEEA 116 Trichomonas vaginalis G3
XP_001320130  74 QLMlq-gyDgNI-YQLRVLI--FRIQELLNFEKFKLEMQATQRRI 114 Trichomonas vaginalis G3
XP_001316501  76 WTLls-cvKsLK-IQALVIA--DILQKTLSFEEFYKQMKTINNNI 116 Trichomonas vaginalis G3
XP_001304740  77 ETIan-elLsSN-KMALQIQ--EQLLRSTDFITFREDMIAHNERI 117 Trichomonas vaginalis G3
EAY01939      77 QVIld-giEnNI-QQAISIK--ETLTKAVDFELFRRDMISHNERI 117 Trichomonas vaginalis G3
EAY12401      76 SKIis-nyDlQN-YRAKTIT--ESISKSLDFSKFKEDMLRYKEDL 116 Trichomonas vaginalis G3
XP_002901151  78 EHCqk--aMkVD-PKVEQYL--EIVIASMDYDAFIGLMKSMRARa 117 Phytophthora infestans T30-4
KAE8878721    83 DAIqenlkYeSA-LSTEKRFciQTLLTFDDYDAFCSRISEYAAEK 126 Phytophthora fragariae
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