2CWO


Conserved Protein Domain Family
Suppressor_P21

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pfam11479: Suppressor_P21 
Click on image for an interactive view with Cn3D
RNA silencing suppressor P21
P21 is produced by Beet yellows virus to suppress the antiviral silencing response mounted by the host. P21 acts by binding directly to siRNA which is a mediator in the process. P21 has an octameric ring structure with a large central cavity.
Statistics
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PSSM-Id: 371552
View PSSM: pfam11479
Aligned: 7 rows
Threshold Bit Score: 95.6068
Threshold Setting Gi: 81935899
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2CWO_A       115 TpMHKETASDTLNAFLEEYCRITGL-------AREDALREKMRKVKSVVLFHHSELLKFEVTENMFSYTELLkLNLS-LR 186
AIA09078      95 EkLLCTSAVDVMGFFVMRYMSSSHT-------SFESVMRTELKLVVKVVLSDLSRAHKLDFSERAFAAYGIL-LQKG-TV 165 Citrus tristeza...
Q5G7F9        97 DqLN-LESKELLAFFVKYFTNITPT-------SFDHAIEYSVRQLVSAVLLHLSSESGLDISANTFRQNVLLrSNNK-VI 167 Mint virus 1
O89912        95 TpMHKETASETLNAFLEEYCRITGL-------TREDALREKMRKVRSTVLFHHSELLKFEVTENMFSFTELLkLNLS-LR 166 Beet yellows virus
YP_008858538  94 TpMHAESASATFEAFLREFCKITGL-------TRENAMLENMRKVKSTVLFHHSDLLGFEITENMFR-YSEL-LKLNlKL 164 Carnation yello...
AKT94765      95 D-IIDLSTEDTLRFFVARFMEVTSH-------TKDESLSYNVRDIVNTVLRRISSERSLDVSTNTFKQCDLLrMQKS-LR 165 Tobacco virus 1
Q65860        92 E-FNCSSNQDVVKMIIRNYINTHPSnsrerpvTFEQIQSFSMRGVIKTSLQNLSYKYKFEVTINYFKCNALLdVKMGvSV 170 Beet yellow stu...
2CWO_A       187 VISSQILG 194
AIA09078     166 STVCGQFD 173 Citrus tristeza virus
Q5G7F9       168 VEWTRRLG 175 Mint virus 1
O89912       167 VISSQILG 174 Beet yellows virus
YP_008858538 165 RVVSSRIL 172 Carnation yellow fleck virus
AKT94765     166 SVWKHTLG 173 Tobacco virus 1
Q65860       171 KTFVENYL 178 Beet yellow stunt virus
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