Conserved Protein Domain Family
Syntaxin-5_N

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pfam11416: Syntaxin-5_N 
Syntaxin-5 N-terminal, Sly1p-binding domain
Syntaxin-5_N is the Sed5 N-terminal and the N-terminus of Syntaxin-5-like proteins. It is the region of Syntaxin that interacts with Sly1p, a positive regulator of intracellular membrane fusion, allowing SM (cytosolic Sec1/munc18-like) proteins to stay associated with the assembling fusion machinery. This allows the SM proteins to participate in late fusion steps.
Statistics
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PSSM-Id: 402844
View PSSM: pfam11416
Aligned: 31 rows
Threshold Bit Score: 30.8782
Threshold Setting Gi: 0
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_007674919   2 ATTHTIQDRTAEFRSILLQAQK 23  Baudoinia panamericana UAMH 10762
EEN60472      33 SAEMSCRDRTSEFISAVKSMQM 54  Florida lancelet
GAC73840       8 YYGHSVKDRTSEFHGLVESIAS 29  Moesziomyces antarcticus T-34
CCF47929       9 YYGQSVKDRTTEFHSLVDSISS 30  Ustilago hordei
CCD25008       4 LQPRNIRDRTSEFQQSVLTCKK 25  Naumovozyma dairenensis CBS 421
XP_011273337   7 NQPQDIRNRTVEFQQCVNTFNK 28  Wickerhamomyces ciferrii
ESW96345       3 VYPPNVQDRTLEFLQCVSTFNK 24  Ogataea parapolymorpha DL-1
EDQ63430       8 lPSTSGRDRTSEFHAIVDRLRK 29  Physcomitrella patens
XP_002952243   4 PQPASLRDRTPEFLAIAERLQR 25  Volvox carteri f. nagariensis
XP_006356621   5 VASASFRDRTQEFQSIAERLKK 26  potato
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