Conserved Protein Domain Family
DotA

?
pfam11388: DotA 
Phagosome trafficking protein DotA
DotA is essential for intracellular growth in Legionella. DotA is thought to play an important role in regulating initial phagosome trafficking decisions either upon or immediately after macrophage uptake.
Statistics
?
PSSM-Id: 402825
View PSSM: pfam11388
Aligned: 23 rows
Threshold Bit Score: 106.238
Threshold Setting Gi: 698841900
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
KTD17518      465 TDSGTGLGESifPTILPAVTSGF-ASNNT--CSpGQSAPnyLCQWMQG---------DPA-PINAVVGLIDGSNVgqerv 531  Legionella jo...
WP_043873721  468 TDTNTGLDSS--TIDTSNLSASFvGGTGC--STtAPFNN--LCTWLSG---------NQG-TVSTIITAINGSTA----- 526  Legionella ma...
WP_043873720  472 TDTNTGLDSS--SIDVSSLLTPL--SSPG--CN-GTFPS--LCTWLSKy-------pSGLsAMQSLTMLIDNYNPa---- 531  Legionella ma...
WP_058530437  456 TDTNTGLEGS--QFDSQIPLNAF-SQNKQ--CS-GTYAA--LCQWLGG---------NQT-AIQNMVGLINGSTLvg--- 514  Legionella ru...
KTC95025      481 VDTGSGLNES--SFDENLPLTPF--SNGS--CV-GTYAT--LCEWLDG---------DSS-PIKAVIGLINGSTFl---- 537  Legionella fe...
WP_045100780  456 TDSNTGLDGS--SFDASLPGSAF-GSNGNlgCS-GNYAN--LCVWLTGgipsqkllkDASdSVANVISLINGSGV----- 524  Tatlockia mic...
KTD50385      463 TDSDSGLDSS--SADISTMTNAF-GGDGT--CK-GQYSE--LCQWYQG---------DDK-YVKHIAGLIDGSTV----- 519  Legionella qu...
KTD64388      484 TDKDTGLDSS--SFKIENIIKSF-GSNNK--CK-DPYQD--ICEWMQT---------NQA-PMNNVVSLINGASV----- 540  Legionella sp...
KTC85192      493 TDTKTGLSGS--KFDLTTVLKSFgETTGK--CAtGTQGN--LCVWLGG---------SSS-AITPVIGLINGSNTtg--- 553  Legionella br...
KTD22013      467 TDTGTGLNGS--KVDLSQLNNAF--VGGK--CStGETPSvyLCNWMNG---------DPT-LINQVIGLINGANLgspl- 529  Legionella la...
KTD17518      532 nfpASKDIAGLN----TGGQDVSAAKGA-ASSTVYGFLHNSMMVQLPGQPGQNPPQ 582  Legionella jordanis
WP_043873721  527 ---GNNPIPA------NVSPTAHQAVGSlGSSTATGYINNSVMVNLPGQPGMAPPS 573  Legionella massiliensis
WP_043873720  532 --aATPAIILSV----IPSASSTPVLGN-GSATTVGFINNSVLITLPGQPGMTPPA 580  Legionella massiliensis
WP_058530437  515 --pNNPPLSPPTf---GNNAAQKAQSGV-LSSTVYGFINNSVMVNLPGQPGLNPPQ 564  Legionella rubrilucens
KTC95025      538 --pSKEIIHSPPtv-dPNTSGLVAISGP-GSSTVNGFITNSILVNLPGQPGMTPPQ 589  Legionella feeleii
WP_045100780  525 ----VPTLSTPT----FNATSTKAIPPP-GANTVFGFVNNSSMVNLPGQPGLTPPQ 571  Tatlockia micdadei
KTD50385      520 ---LNSGLDVPT----FNSISHKAVTGL-GSSTTYGYISNASMVQLPGQPGIV-TA 566  Legionella quinlivanii
KTD64388      541 ---LSRPQDPPD----VTSLDHKAVSGA-GSSTVYGFIDNSLLVNLPGQPGLKPPQ 588  Legionella spiritensis
KTC85192      554 -qpGQPQLPTSNtisdITGTKGDAYSGG-YSSTTFGYINNALMLHLASQPGLTPPA 607  Legionella brunensis
KTD22013      530 dmpGSSAIPG------LQAGTSDAQTGA-FSSTVYGFLQNSMMVQLPDQPGQSPPQ 578  Legionella lansingensis
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap