Conserved Protein Domain Family
DUF3173

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pfam11372: DUF3173 
Domain of unknown function (DUF3173)
This family of proteins with unknown function appears to be restricted to Firmicutes. These proteins appear to be distantly related to HHH domains and are therefore likely to be DNA-binding. Genomic environment-visualisation confirms the likely function as being DNA-binding, as this short protein lies very closely between an integrase and a replication protein (http://www.microbesonline.org/).
Statistics
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PSSM-Id: 402810
View PSSM: pfam11372
Aligned: 14 rows
Threshold Bit Score: 81.9364
Threshold Setting Gi: 81453972
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q8DZ69                    2 RTATYKDLMNLGFPEHTSRDIIREAKKIAVKKfeearkvdhnavqlSKSPFDNRRLGIAPAEIVEQLIGIPL 73  Streptococcu...
Q8DX67                    4 NVMTNKDLIEMGYCPSTANHIIHQARNLMVER--------------GYTFYDRKRLMVVPRSAVSEVIGLEV 61  Streptococcu...
Q5M297                    4 NLISNKELIEMGYRPHTANDIIHQARELLVSR--------------GYTFYNRKRLMVVPKSVVNEILGTEV 61  Streptococcu...
bcmhgsc:HMPREF0351_10713  7 fMVNRAILIEMGFKPSQAARMIKESKAYLARIe-------------GIDFYNNRQVGVVPSRVIEHLFHIQV 65  Enterococcus...
bgi:05SSU0863             5 KMIEKSHLIKMGFTKYQATGIIKQVKLNLVNQ--------------GYYLYNNKRLAIVPASAVESLIGVTi 62  Streptococcu...
KRK48612                  3 PMVNYKDLIRLGFKEHQARDIIHQAKINLVEQ--------------GLPLYNGKRIGVVPVRAVEKIVGFPL 60  Lactobacillu...
Q74LF1                    3 ELVDFTDLVNMGYKPSQARTIIRIAKNNMVKA--------------GYGLYNNKRLGIVPVKAVEQITGLSL 60  Lactobacillu...
Q832I5                    2 KTATRQDIIKLGFSQYYADKIFKECKTLLITK--------------GYSFYKNKKIKRIPVSIIEEVLHISW 59  Enterococcus...
Q839K0                    2 LIVTKEDLMNLGYGKYQAEDIIRKAKAVMVSK--------------GYAYYLNKRLGRVPVGAVESVLGIEL 59  Enterococcus...
WP_012009122              3 TTICKDDLIKIGYKKYQAVNLIREAKAIMVQK--------------GCPYYNNKRLGRVPRDVVESILGVSL 60  Bacillus pum...
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