Conserved Protein Domain Family
Methyltransf_34

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pfam11312: Methyltransf_34 
Putative SAM-dependent methyltransferase
This family of largely fungal proteins are likely to be a methyltransferase. This was determined through multiple motif screening in yeast.
Statistics
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PSSM-Id: 402764
View PSSM: pfam11312
Aligned: 81 rows
Threshold Bit Score: 292.943
Threshold Setting Gi: 74694798
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EER43806      86 LSDRDsktealsrpLSELVQILKTHLYHRDFISAFADanEELlkAYALRWSAGRALGYAGIFASVleMIIQhrtVvagdd 165 Histoplasma cap...
EGV61268      42 LDSPD---------LPEFIQVVKGSLYERQFLEAFDDdnKRF--AYAARWTPARSLAYASLFSSLepVKGL---Fedpd- 106 Yamadazyma tenu...
XP_002615699  62 LASED---------LPDMIQLVKGELFKRDYLSAFNNddKRF--AYVARWSPSRALAYSSLFASLesVAKM---Fedpe- 126 Clavispora lusi...
EDK37342      52 LESPD---------LQQHIQIVKERLYHRDYLAAFDNddKRF--AYASRWSPARALAYASLFSAMdpVRDL---Fsdpe- 116 Meyerozyma guil...
CAR66293      59 LDSED---------LQKHIQSVKGDLYNRNYMSAFGNddKRF--AYASRWTPARALCYSSLFATLepIRLL---Lekpe- 123 Debaryomyces ha...
XP_001385111  35 LEAPD---------LQEMIQVVKRDLYNRDYLAAFGSddNRF--AYVSRWTPARALSYSSLFSSLheFQSS---Lddpe- 99  Scheffersomyces...
EGW34449      51 LDSPE---------LLEHIQVVKGHLYNRDYLAAFDDdnKRF--AYAARWTPARALAYTSLFASLdpVRDL---Lkdpe- 115 Spathaspora pas...
EMG49035      41 LQSPD---------LQDYIQLVKGDLYNRDYLTAFNSddKRF--AYASRWTPARSLAYASLFASLepIKEL---Medpe- 105 Candida maltosa...
EDK41950      52 LKSPN---------LQEHIQQVKGDLYRRDYLAAFDNddKRF--AYASRWTPSRALAYSSLFSSLepVNKL---Lgdeh- 116 Lodderomyces el...
CCE41528      72 LDSHE---------LDSFIQKVKGDLYNRDYIAAFNDdnKRF--GYAARWSPSRALAYASLFSNLepITEL---Lqese- 136 Candida parapsi...
EER43806     166 kagqHVVCIGGGAgAEIAGLAAAWRwlhdggisnapaavtsdraaefssmnnNfrnisvenemepaqipdtdtelagqqP 245 Histoplasma cap...
EGV61268     107 -sttSVLCVGGGAgGELVGLASVFCrl------------------------kEhn----------------------stS 139 Yamadazyma tenu...
XP_002615699 127 -rknRVLCVGGGAsSELVGMASLFCam------------------------kQnn----------------------aeT 159 Clavispora lusi...
EDK37342     117 -ntcRVLCVGGGAsSELVALAALFArs------------------------kEhy----------------------stS 149 Meyerozyma guil...
CAR66293     124 -gdkRVLCVGGGAaSELVGLAAVFCrl------------------------kEyc----------------------skS 156 Debaryomyces ha...
XP_001385111 100 -kevKALCIGGGAsSELVALASVFCrs------------------------kEyn----------------------skS 132 Scheffersomyces...
EGW34449     116 -skkSVLCVGGGAsSELVALGAVYCrl------------------------kEyc----------------------sgS 148 Spathaspora pas...
EMG49035     106 -sikNVLCVGGGAsSELVALGAVFCrl------------------------kEyn----------------------sgS 138 Candida maltosa...
EDK41950     117 -akiNVLCVGGGAgSELVGLGSVFSrl------------------------kEfh----------------------pnS 149 Lodderomyces el...
CCE41528     137 -kvkRVLCVGGGAaSEIVGLGAVYCrl------------------------kEfh----------------------pnS 169 Candida parapsi...
EER43806     246 FSNFSITSIDIADWSSLVNTLNKAILSEs-iPSsmacpaplipptnpesqvdGQFQVHFKKADVLKL---TDQEMRSlFs 321 Histoplasma cap...
EGV61268     140 TSNLVVKIVDIADWSAIVTNVTKYMQQNwlyKP-------------------EKLTTQFIHKDILGNgf---sAYGD-L- 195 Yamadazyma tenu...
XP_002615699 160 PSSLQMDIIDIADWSTIVHNISSFIQKQwlyDA-------------------SKFSAKFIHGDVLSEss-aSLQLSQ-L- 217 Clavispora lusi...
EDK37342     150 PSNLDMTIVDIADWNTVVSNLSAHIRSKwvyKP-------------------ESFNASFLHKDILSL----ELDYSS-M- 204 Meyerozyma guil...
CAR66293     157 NSSLQLDIIDIADWSTIVGTLTSYVKENwiyNA-------------------AGFNTNFIHDDILTAdv-aKLDYPK-L- 214 Debaryomyces ha...
XP_001385111 133 NSSLSIDIIDIADWSKVVSTLTTYIKKNwiyNP-------------------DKFSTNFIFGDVLDQnanHGINYNQ-L- 191 Scheffersomyces...
EGW34449     149 ASELNIQLIDIANWKTVVESLTSYMKENwiyRP-------------------EKLTANFICDDVLTVsk-eSLTLET-L- 206 Spathaspora pas...
EMG49035     139 PSTLNIKLIDIADWSKVANNLTTYIKENwvyRP-------------------EKFNSEFICDDVLTAsp-eSLNLES-L- 196 Candida maltosa...
EDK41950     150 DSCMNVEIVDIADWGKVTTNVASYMKSNwvhRN-------------------ECLNSKFLCADILATnl-eLIGIAD-M- 207 Lodderomyces el...
CCE41528     170 PSRLDIDVVDIADWTVVVNQLTNYVKQNwvyKE-------------------HNFNTQFKHEDILSTki---dDLAS-F- 225 Candida parapsi...
EER43806     322 pprnvngdmkfdwlamkrnenMLVTLMFTLNELFLTSISMTTAFLLRLTDMLHPGTILLVVDSPGSYSTVSFatskeNSt 401 Histoplasma cap...
EGV61268     196 ---------------------DLITLMFTTNELFSEKRAETIRFLQTLNRSCKQGAHLLIAESAGSYSHITV-----GT- 248 Yamadazyma tenu...
XP_002615699 218 ---------------------DLITLLFTTNELFCEKKTETIKFLQSLSAHCRQGTLLLITESAGSYSHITV-----GS- 270 Clavispora lusi...
EDK37342     205 ---------------------DLVTLLFTTNELFCEKRSETVKFLQRLNSQCHSGSLLLIAESAGSYSHITI-----GS- 257 Meyerozyma guil...
CAR66293     215 ---------------------DLITLLFTTNELFCEKRAQTVQFLQSLNTHCRKGCYLLIAESAGSYSNITI-----GT- 267 Debaryomyces ha...
XP_001385111 192 ---------------------DLITLLFTTNELFAEKRPETIKLLQLLNRQCKQGSLLLIAESAGSYSNVMV-----GS- 244 Scheffersomyces...
EGW34449     207 ---------------------DLVTLLFTTNELFAEKRKETIRFLQNLNKYCKPGCLLLIAESAGSYSHITI-----GE- 259 Spathaspora pas...
EMG49035     197 ---------------------NLVTLLFTTNELFAEKRKETIKLFQQFSSRCQKGCLLLIAESAGSYSHITI-----GE- 249 Candida maltosa...
EDK41950     208 ---------------------DLVTLMFTTNELFSEKRKDTVKFLLALNQNCKPGSLLLIAESAGSFLNIKI-----GE- 260 Lodderomyces el...
CCE41528     226 ---------------------DLITLLFTTNELFAEKRKETIKLLQTLSTGCKSGTLLLIAESAGSFSHITI-----GN- 278 Candida parapsi...
EER43806     402 qkssnsstpppsredhttrqdvkasatksnhpmsqRNYPMRFLLDHALLSVAd------GNWERVVSEDSRWFRRDTtLL 475 Histoplasma cap...
EGV61268     249 -----------------------------------KKFPVQFIIDTVLLGKQge---dtGAWDLVDQSDSCWYRIDEkEV 290 Yamadazyma tenu...
XP_002615699 271 -----------------------------------KKFPVQFLIDTILLGKPgd---dnGAWQIIDQSESCWYRINDkDI 312 Clavispora lusi...
EDK37342     258 -----------------------------------KKFPVQFLVDTILVGRPda---ndGAWEIIQSSESCWYRVDTrEV 299 Meyerozyma guil...
CAR66293     268 -----------------------------------KKFPVQFLIDMILIGKPge---nsGSWEIVQQSESCWYRVNKkEI 309 Debaryomyces ha...
XP_001385111 245 -----------------------------------KKFPVQFLVDMILVGKQga---ndGDWEIVEQNESCWYRINQkEV 286 Scheffersomyces...
EGW34449     260 -----------------------------------RRFPIQFLIDTILVGKSge---dnGAWETIQKSESCWYRIESkQV 301 Spathaspora pas...
EMG49035     250 -----------------------------------RKFPIQFLIDTILVGKPne---nnGAWEIVNQSESTWYRINEkEV 291 Candida maltosa...
EDK41950     261 -----------------------------------RQFPVQFLIDTILVGKPgdsgdntGAWDIISQSESIWYRIMErEV 305 Lodderomyces el...
CCE41528     279 -----------------------------------KQFPVQFLIDTILVGKQge---gnGSWEIISEKESIWYRINErEV 320 Candida parapsi...
EER43806     476 KYQVgdgiGLEDMRVQIHVYR 496 Histoplasma capsulatum H143
EGV61268     291 DYPM----KLENMRFFYRLYE 307 Yamadazyma tenuis ATCC 10573
XP_002615699 313 NYPV----KLENMRFFYRLYQ 329 Clavispora lusitaniae ATCC 42720
EDK37342     300 TYDM----KLENMRFFYRLYR 316 Meyerozyma guilliermondii ATCC 6260
CAR66293     310 DYKM----KLENMRFFYRLYK 326 Debaryomyces hansenii CBS767
XP_001385111 287 EYPM----KLENMRFFYRLYR 303 Scheffersomyces stipitis CBS 6054
EGW34449     302 DYPM----KLENMRFFYRLYR 318 Spathaspora passalidarum NRRL Y-27907
EMG49035     292 DYPM----KLENMRFFYRLYC 308 Candida maltosa Xu316
EDK41950     306 TYEL----NLENMRFFYRLYR 322 Lodderomyces elongisporus NRRL YB-4239
CCE41528     321 TYPL----KLENMRFFYRLYR 337 Candida parapsilosis
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