Conserved Protein Domain Family
Glyco_hydro_129

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pfam11308: Glyco_hydro_129 
Glycosyl hydrolases related to GH101 family, GH129
This family of bacterial and lower eukaryote glycosyl hydrolases is related to CAZy family GH129,and distantly to GH101, and is made up of sub-families GHL1-GHL3. In the example Swiss:C02A26, the substrate-binding Asp is residue 596, the nucleophilic Asp is residue 706, and the proton donor Glu is residue 747.
Statistics
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PSSM-Id: 402761
Aligned: 9 rows
Threshold Bit Score: 410.661
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6LJF4                  389 NLQKVGLKKLWLGLDNWMPAFYQPEVVEQAKKAGYLVGVYDSYNTAIAPGVNDAWLTAQL--PQAMREECAIEKADGNKK 466 Phot...
Q7NY91                  378 ALQAAGLKRLWLGADNWEGGLWQPQAVKAGVDAGYLMTAYDSYETALQLGYREDWLTAQQ--GEAIYRQCGVTLASGKKK 455 Chro...
WP_012600724            407 NLNKAGLNKLWLGFDNWMPAFYQPNAVELAKQSGYLVGTYDSYNTAIPAKLNDNWLTAQL--PKPMRESCAIEMADGSLK 484 Vibr...
Q9KMR6                  375 TLQQAGLSKLWLGLDNWMPAFYQPQVVDSAKQAGYLIGVYDSYNTAIEKGINDSWLTAQL--PDRMRENCAIEKADGTLQ 452 Vibr...
Q2SB82                  404 ALRKAGLTSAWLGANDWLDALWHPQSVKEAKAAGYLVGVYDSYGSIHAPDEPRTWLTAQV--GRENWEKAPYRREDGSIV 481 Hahe...
WP_011874668            285 RLRELGIDRMWLGYDADGRPM-SPEAVKAAKDAGYLVGPYDSWANAQDPAQADN---PSSrwPAPVWQEACVREADGEVM 360 Sacc...
PRJNA295544:AOD64_09840 397 EMKTAGIDNAWIGLPNWEQGYMQPDFVTEAKKMGYLVGPYDSYHSIHEKA-DKNWNTASFt-DPSLYEEATVTKRNGEKV 474
Q024H3                  281 EAKAAGVEKMLIH------GTSSAADMKAINELGYLTSEYDVYQDVM--GVKDESEIASR---AEWVPDNVVLRADGTRM 349 Cand...
WP_011704581            364 ALQQAGLRKLWLGTPQWTAALQQGYALTAAQRQGYLVGSYDSYDTAIAPGTNDSWLTAQL--PPEIGKRCAIFEANGEPK 441 Aero...
Q6LJF4                  467 KGFR--GNGVYLN--PSCNRDYVENRIKDVIN-YGRFNSIFLDVDATAMAREDYsVSSDGMNQTDMLAAFNARMQWIATD 541 Phot...
Q7NY91                  456 AGFQ--QSGYYTN--PDCVRDTLKQRTRALHA-ATGFNSWFLDAYATGMVFDDY-TPGRQTGKAEMAAGYEKSMQWVADA 529 Chro...
WP_012600724            485 KGFR--GNGFYLN--PNCHLDYVKQRAADIMR-FGHFNSLFLDVDATAMAREDY-SDN--SSESDMLSAFNNRMQWLSEQ 556 Vibr...
Q9KMR6                  453 LGFR--GNGFYLN--PACELGYVKQRVQDILH-FGHFNSLFLDVDGTAMAREDY---RSRSNETAMLAAFNTRMQDIANT 524 Vibr...
Q2SB82                  482 SGFS--SVGAYAN--PLAIKEYAEQRMTAVTR-EARLNSLFLDVDATGMIYEDY-TEGRKTSDAQDVAARTQRLNFPREE 555 Hahe...
WP_011874668            361 PGFR--DRGCYLSseAFARNPRLMADRTGEMT-ANGANSYFLDVDAAGELHTDH-SPAHPMNKERDRRNRLDRMGRLAGD 436 Sacc...
PRJNA295544:AOD64_09840 475 QGFL--GRGRKLN--PTLSLPSVKERMNDILQnGPKYNSWFIDCDATGEIYDDY-SAKHITTQEQDLKARLQRMDYIAQE 549
Q024H3                  350 PAWLtwDKKQYMKrcPTFWLHTAQRVIPKALA-EHPYLGRFIDVTTAENLYECY-DEKHPLDKTEKRQRGEELLGYV-RS 426 Cand...
WP_011704581            442 PGFG--GEGVYLN--PGCTLPFAKSRMSELAK-ASGINSLFLDVDGTAMASNDY-NPAHQQGSQAMIADRNARMSWVGER 515 Aero...
Q6LJF4                  542 QHVLLGSEDGNALTTQGIAFAHGMETVGF-GWTDPDMKSNRQSPYYLGAWY--PDQKPAFFFQS----AQVKEPYKTLLF 614 Phot...
Q7NY91                  530 YRLPVGSEMGNAATSRGIAFAHGMQAPVM-GWGDADLQKNKQSPYFLGRWY--PSDQPETFFKK----VPLKQPYRDLYF 602 Chro...
WP_012600724            557 PSLVLGSEDGNSLTTKGIAFAHGLETVGF-GWTDIDMKENRRSPYYLGRWY--PDHKPDFFFKP----ADVKEPYKSPLF 629 Vibr...
Q9KMR6                  525 PKLILGSEDGNALTTQGLVFAHGMETVGF-GWTDQAMKSDKQSPYYLGNWY--PDEKPDFFFKS----AQVKEPYRSLLF 597 Vibr...
Q2SB82                  556 LALVTGSEGGSALFANAIEFAHGMTITPF-SWTDPDTGKNRQSTYYRGNYW--PPEAPSLFFAT----KPIKPALRNIYY 628 Hahe...
WP_011874668            437 --LVLGSESAGAWSAPVLSYNHGSST-----PVSDHLWELEKDKDFWGGYA--PEGAPEAFFEP----VELPADAAKAMF 503 Sacc...
PRJNA295544:AOD64_09840 550 KGMVVGSEGGNDFASSTIAFAHGIETPVI-KWDDEDMRKNKTSPYYVGGYWspNQNVPEKYAKQ----VPLKEEYKQVYL 624
Q024H3                  427 LGLVTGGEHGRWWAVPYLDYIEGMMSGGStSWPSGWLKRPKT--------------KDEAFTDPngraFPKWEEYEKWGI 492 Cand...
WP_011704581            516 LGLVLGSEDGNALTSKPLLFAHGIQSWGF-GWTDAAMRKQAKSPYYLGKWW--PDEAPQVFFQP----ARLKPRYLKTVF 588 Aero...
Q6LJF4                  615 APQYKIPLYQTVFHDELINSHHWHSDSLKF-----NNVQMERDLIAMLYNTPAMVHLS-RDEANTinapRLQALKHYQSG 688 Phot...
Q7NY91                  603 SAPYRLPLYQAAFHGSVITTNHWLYDNLKF-----SNAYADNLLAQWLYNVPPLFHLS-AASLRA----RLPQLQCADRA 672 Chro...
WP_012600724            630 SPQYRIPLYQAVFHDEVINTHHWHSDSLKF-----TNVQAERDLTAMLYNTPPMVHLT-RDEALSssspRIKALKHYQDG 703 Vibr...
Q9KMR6                  598 APEYKVPLYQAVFHDELISSHHWHSDSLKF-----SNVKAVRDLRAMLFNTPAMVHLS-RDETRKns-aRIEQLKHYQQG 670 Vibr...
Q2SB82                  629 NPAYRLPLYQLALHESVVATLHWEYPSLKF-----KETRVDVGLLQLLYMIPPMYHLN-AANLKR----DLPVIAAYDKV 698 Hahe...
WP_011874668            504 APQYRVPLYQTVLHDSVIGTDRWELPWSKL-----PRQATDRVAMAMLHNTPLNLVLN-ETELDA----HGAEIAALQRY 573 Sacc...
PRJNA295544:AOD64_09840 625 NPVYSVPLYKLVYNDAVITTHHWEWGSLKI-----KDEVGNRMLYELLYNVPPLYHLD-EVEWNK----HKQEITKHLKV 694
Q024H3                  493 GHEYRVPLWELVFHDSVISTWYWG-DSSDFlleaaPDVTAKKDAFNILYGTMPMMWANgEGSWVK----NREMFLRTYRN 567 Cand...
WP_011704581            589 NPADRLPLYQAVFHDSVLNSHHWLLDNLKF-----PGIKEERALLGLLYNTPPLVNLS-RSTLAS----RLPELVRLDSQ 658 Aero...
Q6LJF4                  689 FLPIHKQLWDKALVNFKWLDKQGLLQQTT 717 Photobacterium profundum
Q7NY91                  673 FRPLHEQLATQALTGFAWLNAEHTLQQTR 701 Chromobacterium violaceum
WP_012600724            704 FEPMHEQLWDKQLVDFDWLDKSGEVQQTE 732 Vibrio atlanticus
Q9KMR6                  671 FLPLHEQLWDKALVDFRWLDKQGQVQQTR 699 Vibrio cholerae
Q2SB82                  699 FRPWHEKLYRTRMTGFEFLSLDRLLQSTR 727 Hahella chejuensis KCTC 2396
WP_011874668            574 FAPLHQAAATEPMTGFRWLTADHLVQRTT 602 Saccharopolyspora erythraea
PRJNA295544:AOD64_09840 695 WNEFHKKAVKEEMTNFAYLSEDKLVQSAs 723
Q024H3                  568 ACKVHEAVATAEMVSHEFVTADRAVQRTR 596 Candidatus Solibacter usitatus Ellin6076
WP_011704581            659 FGPLHEALWDKALVGFRWRDGVGRVQETR 687 Aeromonas hydrophila
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