Conserved Protein Domain Family
FAF

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pfam11250: FAF 
Fantastic Four meristem regulator
FAF is a family of plant proteins that regulate the size of the shoot meristem by modulating the CLV3-WUS feedback loop. The proteins are expressed in the centre of the shoot meristem, overlapping with the site of WUS - the homeodomain transcription factor WUSCHEL- expression. FAF proteins are capable of modulating shoot growth by repressing WUS in the organising centre of the shoot meristem. The ability of plants to form new organs throughout their life cycle requires tight control of the meristems to avoid unregulated growth. Plants have evolved an elaborate genetic network that controls meristem size and maintenance. WUS and the CLAVATA (CLV) ligand-receptor system are at the core of the network that regulates the size of the stem cell population in the shoot meristem.
Statistics
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PSSM-Id: 402713
View PSSM: pfam11250
Aligned: 69 rows
Threshold Bit Score: 29.769
Threshold Setting Gi: 1433402739
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002972616      34 EFPPPMPSLArtSyNhlplqvPWTLLSANRSNNRVVLHEIKAAHGAQLmlFQPIRSQGRLVLQM 97  Selaginella moellendorffii
ERN07472         150 NFPPPLSTL---SkNg----qVSYFLKPVKTEGRFILREVVIL-RQEV--LRACRENGRLRLHM 203 Amborella trichopoda
KRG96879         132 SFPPPLSSL---NrNg----kPSFYLRPVRKDGRLELTEVRIQ-RSEI--LHASRHNGRLTLRL 185 soybean
XP_003535351     133 NFPPPLSSL---NgNg----qPSFILVPVRKNGRLQLTKVRIK-RPKI--LYATRQDGRLRLLL 186 soybean
EFH70860          89 KFPPPLSSF---NgRg----kRSFYLRPVRKDGRLELTQVMIN-RPEI--FHASREDGRLRLHF 142 Arabidopsis lyrata subsp. l...
XP_006361886     148 EFPPPLSSL---SqDg----kPNFFMRAVRKDGRLELTEVKID-RPKT--FRASRQDGRLRLHL 201 potato
XP_019071453      55 SFPPPLSSL---NqDg----kPIFSLKPTRKDGKLELNEVKMDIPSSI--VVTSRQQGRLRLNL 109 tomato
JCVI:AT3G63020.2 111 DLPPFLTTLDcnGr-------PRFHHRRVRSEGRLEIASVAVDSPE----IVSVR--GREGLRI 161 thale cress
XP_003576304     186 EFPPAIRSV---GrGg----rPSVCFRASRGEGRFVLTRVVIP-GKEL--LHASRGGGRLRLQF 239 stiff brome
XP_003577033     181 TFPPPIRSIAsgGrGg----kPSVCFRSFRAEGRFVLVEVVIP-GKEL--LHASREGGRLRLQF 237 stiff brome
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