Conserved Protein Domain Family
SelK_SelG

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pfam10961: SelK_SelG 
Selenoprotein SelK_SelG
This entry inclues a group of eukaryotic selenoproteins, such as SelK and SelG. SelK seems to play an important role in protecting cells from endoplasmic reticulum stress induced apoptosis. SelG may be involved in regulating the redox state of the cell.
Statistics
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PSSM-Id: 402509
View PSSM: pfam10961
Aligned: 37 rows
Threshold Bit Score: 29.176
Threshold Setting Gi: 0
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_011115171  14 TYLS-SGQVLTs-PPLTARITRFSESAIQFFGLYFVSLLSFDAYSAAenSSFATQNNTsmqgsgartsggstgFGGGSG- 90  Dactylellina ha...
Q179T4         2 VYIArDGSVHEtqPWSVQRFIGMITGFLGLIAMFFKTMFNMDSNQPSrgQDSSGIHWRg--------------GGGGGPp 67  yellow fever mo...
ETN67798       2 VYIGrDGVVRAsqPWGIERIKGIIRGFFNFLLMFFRTMLDFNLGAGSgaGNQRGSgs---------------gGGGDGPp 66  Anopheles darlingi
XP_001237299   2 VYISrNGAVQEaqPWGVDRIKGLIMGFFNFLVMFFRTMLDFQGGGGSggRDTTRGygg-------------sgGGGGGGp 68  Anopheles gambi...
XP_001845376   2 VYVArDGTVHQsqPWGVQRLLGLITGFFNFFVMFFKTLFGDLKPSGSgdAASSGSSRRgg------------gGGGGPPg 69  southern house ...
XP_002070902   2 VYIDrNGRVWEkrPWDWQRIVEIFFGLWYMIVQFFQTLVAPFNGNGNgnNDNQRRSNWggg---------wggGGGGGGg 72  Drosophila will...
XP_002134105   2 VYIDrNGRVCEkrPWDWPRIVEIFLRIWYIIKQLFLTFLAPFDGKSn--NDNRRGGgsg-----------wggGGGGGGg 68  Drosophila pseu...
Q7Z2C4         2 VYIDhNGRVWEkrPWDWRRIVELFVGIWFAIKQLFLTFLAPFTGNNn--QANPRRGNgwggg------ggwggGGGGGGg 73  fruit fly
KMZ09375       2 AYVDqYGRLWEkrPWDLKRVLDIFVGIWFAVKQLFASFLSPFTGNDSn-GDNFRRGNgwgsssw--gggggggGGGGGGg 78  Drosophila simu...
XP_001967374   2 VYIDhNGRVWEkrPWDWRRVVELFFGIWFAIKQLFASFLAPFNSNDn--SNSQRRNNWdrwgg------ggggGGGGGGg 73  Drosophila anan...
XP_011115171  91 ---------------------SGG 93  Dactylellina haptotyla CBS 200.50
Q179T4        68 ppggprrrpigrvmtlsdctvPGG 91  yellow fever mosquito
ETN67798      67 rpprrigr----tmtlsdctvPGG 86  Anopheles darlingi
XP_001237299  69 pgggprrrpigrpmtlsdctiPGG 92  Anopheles gambiae str. PEST
XP_001845376  70 ppggprqrpigrmmtlrdctiPGG 93  southern house mosquito
XP_002070902  73 gggg-------------gsggGGG 83  Drosophila willistoni
XP_002134105  69 gggg-------------gggsGGG 79  Drosophila pseudoobscura pseudoobscura
Q7Z2C4        74 gggg-------------rpgsGSG 84  fruit fly
KMZ09375      79 gggg-------------ggggGGG 89  Drosophila simulans
XP_001967374  74 gggg-------------yaggNGG 84  Drosophila ananassae
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