Conserved Protein Domain Family
SAM35

?
pfam10806: SAM35 
SAM35, subunit of SAM coomplex
SAM35 is a family of fungal proteins found in the peripheral mitochondrial outer membrane. It is essential for cell viability. It forms a subunit of the SAM (sorting and assembly machinery) complex and is crucial for the assembly of the precursors of Tom40 and porin, the outer membrane beta-barrel proteins involved in mitochondrial biogenesis. SAM35 is required in order for the Sam50 subunit of the SAM complex to bind outer membrane substrate proteins.
Statistics
?
PSSM-Id: 402440
View PSSM: pfam10806
Aligned: 21 rows
Threshold Bit Score: 126.242
Threshold Setting Gi: 146451232
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Q6FSA5           6 MKVPTPVKWVFDRFPVVQYQTIPQSKAIAYSD--TVNRCFEFrdvkssmhnpeydggnSKNDNSGNDNFQLGVySVhgfe 83  [Candida] gla...
EDK36963         4 LQVPQWVKSVFDTFPLSTYEATPLGDHSD-----IEKSRFYFi--------------sDDPEKAPDHNFILGVdGV---- 60  Meyerozyma gu...
XP_001385699     2 FDIPESVKKLFDTFPLTTYPAIPKTTSGNDEF--IEEKKFYFen-------------eKQSQISTNASFSLGVhNVve-f 65  Scheffersomyc...
Q6BK36           2 FEVPKPIKKVFDTFPLYTYDPIPNNTPSNFQS--IESNKFYFt--------------sSNDQAKDNACFTLGVhNIyl-v 64  Debaryomyces ...
XP_002614194     1 MKVPEPIRVVFDTFPLRTYAPVLDKSTQNDEH------IFFFsk------------kgDSSTTEESECFHLGVhKVn--k 60  Clavispora lu...
CCE86529         2 LQIPPLVKNVFDSFPLRKYGPVLNSSDQSNED------CICF----------------GQASPNAENQFILAVnQTf--e 57  Millerozyma f...
CAY71492         3 tKVPSLVKKVFDTFPLKVYSSDEDADQLEFDEsyFELRRFSF----------------QSTGVSAVAKFQLGVySLs--- 63  Komagataella ...
XP_011274011     5 LKVPAPVKELFDKFPVEQYPAVKQLTPDTKKE--IVNRNYSFsv-------------sSDDKTNGLVTFKLGTyNVy--- 66  Wickerhamomyc...
ybcl:Ecym_8006   1 MEVPAPIKQLFDQFPLVSYGPVAKNDNSLKNE--LQQRTYPFeg-------------nNAIKSSPNDVLKLCVyNVi--t 63  Eremothecium ...
Q759H5           5 tQVPAPIKQLFDALPLSQYGPVPATDDATLND--HAVRSYPF----------------RGGPTDNQPTFRLGVyAVv--- 63  Eremothecium ...
Q6FSA5          84 IGGTDVM--LARDPLCLYAQLSLCKKNNLRL-----------PTKFEEGNNekknqpkldaestldshfttdvagirkpg 150 [Candida] gla...
EDK36963        61 IGVNSKI--IPSTPVALAHSLILCYKNGLKL-----------PRENSKSKTsp--------------------------- 100 Meyerozyma gu...
XP_001385699    66 KGQDGKRkyIPSDPVSLGQALILCHKNKLKL-----------PTTSSTNRSc---------------------------- 106 Scheffersomyc...
Q6BK36          65 NTANGEKk-IPSDPISFGHALILCHKNDLKL-----------PSSGDNVGSks--------------------------k 106 Debaryomyces ...
XP_002614194    61 SLVMDKMvfLPSDPIGLADCLILCHRHNLLL-----------PRDAKDEKSv---------------------------- 101 Clavispora lu...
CCE86529        58 YSINDKVvlLPVDPHALACTLILCHKNKLTL-----------PRKCIKNKDaks-------------------------a 101 Millerozyma f...
CAY71492        64 PCIYDSSilLPVDPLCLSTCLIMCVKNGLKL-----------PQIGGEHGRe---------------------------- 104 Komagataella ...
XP_011274011    67 HLDDNTV--LATDPLCLIAELALSIKNNIKL-----------PKLNNDKSDsn--------------------------r 107 Wickerhamomyc...
ybcl:Ecym_8006  64 HEETKSI--LASDPWCLFIQLAICQKNSVRLckaapnndlliPNSSVQQNDssyp-----------------------lk 118 Eremothecium ...
Q759H5          64 EHESGAF--LAPDPWCLLAQLAVCKRNGLLL-----------PTSTSAPSKg---------------------------- 102 Eremothecium ...
Q6FSA5         151 nKVVILSEKAHkDERLPIL 169 [Candida] glabrata
EDK36963       101 hSILSLSYLAAsNNELPII 119 Meyerozyma guilliermondii ATCC 6260
XP_001385699   107 nSIMKVSFHASpDKQLPIL 125 Scheffersomyces stipitis CBS 6054
Q6BK36         107 hSIMKLSYHASpDNQLPIL 125 Debaryomyces hansenii
XP_002614194   102 hSITELSYLASpDNELPIL 120 Clavispora lusitaniae ATCC 42720
CCE86529       102 nSMIKVNYHASpDKMLPML 120 Millerozyma farinosa CBS 7064
CAY71492       105 tSMVVMAYQASpDSELPLL 123 Komagataella phaffii GS115
XP_011274011   108 nSLFLLSHHANsQGFLPIY 126 Wickerhamomyces ciferrii
ybcl:Ecym_8006 119 hCMLVVSHHAAtSSHLPML 137 Eremothecium cymbalariae DBVPG#7215
Q759H5         103 sCVLLLSRYAAaDRQLPLL 121 Eremothecium gossypii
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap