5HQ4


Conserved Protein Domain Family
Glyco_hydro_97

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pfam10566: Glyco_hydro_97 
Glycoside hydrolase 97
This domain is the catalytic region of the bacterial glycosyl-hydrolase family 97. This central part of the GH97 family protein sequences represents a typical and complete (beta/alpha)8-barrel or catalytic TIM-barrel type domain. The N- and C-terminal parts of the sequences, mainly consisting of beta-strands, form two additional non-catalytic domains. In all known glycosidases with the (beta-alpha)8-barrel fold, the amino acid residues at the active site are located on the C-termini of the beta-strands.
Statistics
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PSSM-Id: 402275
View PSSM: pfam10566
Aligned: 62 rows
Threshold Bit Score: 282.193
Threshold Setting Gi: 524306843
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5HQ4_A          257 DVSWVKPGKYIGI-WWGMHINTHt-WGSGDKHGATTKNTKYYMDFAAKYGFDGVLVegwNTGWdgdwffngdvFSFTQPY 334
CBK67945        302 akgeytYGRGSWS-WIIGMDG-----------STNYKEQLRYIDFSAAMGYQSVLV---DALWd-------------KQI 353 Bacteroides ...
CCZ87836        295 kdytaeYGCGTWS-WIIAGDA-----------SMNMDDQKRYVDFCAAMGYRTVLV---DALWd-------------TQV 346 Bacteroides ...
CDA66999        292 asqkygTGKYAWS-WLIWQDE-----------SCNYNDQKLFIDLAATMGYEYVLV---DALWd-------------TQI 343 Prevotella c...
wustl:BV0973    292 tehtyQMGRGTWS-WILWQDG-----------SINFDDQKKYVDLAAAMGYEYVLI---DNWWd-------------TNI 343 Bacteroides ...
CCZ88351        291 psqeyKFGRSTWS-WIMWQDP-----------SINYDDQIRFIDLASEMGYEYTLI---DGGWe-------------KNI 342 Bacteroides ...
wustl:BV0210    276 DTQWIKPGLVSWI-YWAYNHG-----------SKDYQIVKKYIDFAADFDLPYMLI---DWEWda-------------mG 327 Bacteroides ...
CCZ86135        280 DVSWIKPGVVSWI-YWAYNHG-----------SRDYQIIKKYIDFAADFHLPYMLI---DAEWde-------------mG 331 Bacteroides ...
WP_012376026    309 DTSWIKPGITAWDvWWTGINPTQpgFTGLNSRG-DTRSHKEYIDFAAEMGFPYQLI---DWFWyepm------nnpkADL 378 Opitutus terrae
jgi:AciPR4_1547 328 DTSWIHPGKASWN-WWVDNVNG---KGESGNKEFTTETMKYYVDFAAKSGFPYFFL---DAGWa--------sQDITKTN 392 Terriglobus ...
5HQ4_A          335 DD----FDIAALTKYSKQTGv--QLIGHHETSGNVSN------YRKQ-M-ADAFALYEKSNVSQVKTGYVADggnikrid 400
CBK67945        354 GR----DKIEELAKYGKDKGvalYLWYNSNGYWNDAPqtprgiMDNAiArRKEMKWMQSIGIRGIKVDFFGG-------- 421 Bacteroides ...
CCZ87836        347 GY----DKIEELAAYAKQKNvglYLWYNSNGYWNDAPqgprgkMSNIiErRKEMKWMQRIGIKGIKVDFIGS-------- 414 Bacteroides ...
CDA66999        344 GR----DKIAELSKYAQSKNvslMLWYNSNGVANDAPqgprgiMDNIvArKKEMAWMKSIGIKGIKVDFFGG-------- 411 Prevotella c...
wustl:BV0973    344 GR----ERMKDFIDYAHSKNvdvFLWYSSSGYWNDIVqgptnyMDNPiIrKKEMKWLHNIGVKGIKVDFFGG-------- 411 Bacteroides ...
CCZ88351        343 GR----DRMEELFKYAHQKNvdvFVWYNSNGYWNDAPqdakqcMSNSvArKKEMKWLQKCGVKGLKVDFFGS-------- 410 Bacteroides ...
wustl:BV0210    328 NG----GNLNDAMNYCKEKNvtpLIWYNSSTAWCDPTpl--yrLNTPeVrDKEFEWLKEIGIQGVKIDFFGG-------- 393 Bacteroides ...
CCZ86135        332 NG----GNVEDALAYAKQKNiapLLWYNSSTAWCAFGpl--yrLNKPeMrQKEFAWLESMGVKGIKVDFFSQ-------- 397 Bacteroides ...
WP_012376026    379 TKpaahVDIPGLVAYARERNvrlLLWLDSHD------------VERQgF-DKVFAQIAAWGFAGVKIDFMNH-------- 437 Opitutus terrae
jgi:AciPR4_1547 393 GR----VDVPELVRYAAARNvkvWIWLYSE------A------VMKQ-M-KEAFPVYEQWGVAGMKIDFVNR-------- 446 Terriglobus ...
5HQ4_A          401 kngiarhewhDGQFMVNEYLHNVKLAAKHKISINTHEPIKDTGLRRTYPNWITREGARGQEF-NAWG--TPPNPPEHISM 477
CBK67945        422 ----------DKQMTMQLYEDILSDANEYGLLVIFHGCTLPRGWERMYPNFASSEAVLASENlHFSQg-SCDNEAFNATL 490 Bacteroides ...
CCZ87836        415 ----------DKQVTMQLYEDILADANDYGLLVIFHGCTIPRGWERMYPNYAASEAVLASENmNFSQg-SCDAEAFNACI 483 Bacteroides ...
CDA66999        412 ----------DKQHTMQQYEDILSDANDYGIQVIFHGCTLPRGWERMYPNYVSSEAVLASEN-VFFSdyHAKQEAFELTM 480 Prevotella c...
wustl:BV0973    412 ----------DKQETMRLYEAILSDADDNGLMVIFHGCTLPRGWERMYPNYVGSEAVLASENlIFQQh-FCDEEAFNACL 480 Bacteroides ...
CCZ88351        411 ----------DKQQMMGLYEDILTDANEYGLMIIFHGCTIPRGWERMYPNYVGSEAVLASENlIFNQh-FDDMEAYNACL 479 Bacteroides ...
wustl:BV0210    394 ----------DSIGTMNYYIDLLEDAARHKLLVNFHGAAIPRGWQRTYPNLMSVEAVYGSEWyNNKPt-LTDNAAWHNCT 462 Bacteroides ...
CCZ86135        398 ----------DSISTMNYFVDILEDAAKYHLMVNFHGAPIPRGWQRTYPHMMSVEGVYGAEWyNNKEt-LTDSAAWHNCT 466 Bacteroides ...
WP_012376026    438 ----------DGQETVKWYADVLAAAARYKLMVDLHGAYKPTGLARTWPNYITQEGVLGNEYnki-pwkPGACSTLHTIT 506 Opitutus terrae
jgi:AciPR4_1547 447 ----------DDQEGIQFFYDVARYAAEHHLMVDFHGCHTPWGLMRAYPNVMGYESVLGLEN-NKVGr-RDS--PVDRAV 512 Terriglobus ...
5HQ4_A          478 LAFTRMLAGPMDFTPGIFDLSFngl-gaNTNRP---QTT-LAKQLALYVVLYSPIQMAADLPKNYlakp-dafqFIQDVP 551
CBK67945        491 HPFIRNTVGSMDFGGSALNKYYna--dnAPRGSr-rVTS-DVYALATAVLFQSPVQHFALAPNNLtdapswaidFMKEVP 566 Bacteroides ...
CCZ87836        484 HPFVRNTIGSMDFGGSTLNKYYna--knE-LGGr-mRVTsDVFALATAVLFQSPVQHFALAPNNLtdapawavdFMKKVP 559 Bacteroides ...
CDA66999        481 HPFCRNAVAAMDWGGTIMNKYLsk---dNKSRHr-rYTT-DVFEMASAIMNQAAIQCIAIYPNNLselpqheidFLKSVP 555 Prevotella c...
wustl:BV0973    481 HPFIRNTIGCMEFGGTFLNKRLnr---nNDGGNi-rKTT-DVFQLATAVLFQNPIQNFALAPNNLtdapqvcldFMKQVP 555 Bacteroides ...
CCZ88351        480 HPFIRNTIGCMEFGGTLLNKRHnr---tNDGGTi-rKTT-DVFQLATAVLYQNPIQNFALAPNNLtdapalaidFMKQVP 554 Bacteroides ...
wustl:BV0210    463 LPFTRNVIGPMDYTPCTFTN-----------SQhphITT-DAHELALLVIFESALQHLADRPEGYrqqpvevqnFIRYLP 530 Bacteroides ...
CCZ86135        467 LPFTRNVVGPMDYTPCTFTD-----------SQh-pHITsNGHELALLVAFESALQHLADRPEGYhaqpaeirsFISSLP 534 Bacteroides ...
WP_012376026    507 LPFTRGLLGPMDFTPGGFLNRTpae-fkITQPAe-vIGT-RARQLAMTVVYFSPLLVLCDSPENYrgqp--gveFFRGLP 581 Opitutus terrae
jgi:AciPR4_1547 513 FAWTRLLVGPMDYTAGGFDNQTedsfvaRNATPq-vMGT-RAQQLALYVVYENPIPMVSDSPQNYdgeaapafqFLKDVP 590 Terriglobus ...
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