Conserved Protein Domain Family
MADF_DNA_bdg

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pfam10545: MADF_DNA_bdg 
Alcohol dehydrogenase transcription factor Myb/SANT-like
The myb/SANT-like domain in Adf-1 (MADF) is an approximately 80-amino-acid module that directs sequence specific DNA binding to a site consisting of multiple tri-nucleotide repeats. The MADF domain is found in one or more copies in eukaryotic and viral proteins and is often associated with the BESS domain. It is likely that the MADF domain is more closely related to the myb/SANT domain than it is to other HTH domains.
Statistics
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PSSM-Id: 402258
View PSSM: pfam10545
Aligned: 85 rows
Threshold Bit Score: 60.4045
Threshold Setting Gi: 665399568
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9XV35                   12 LINAIRNRPVIWDKNYfGESNYRTLKTSCLREVTSELnsMFQMP----IkftcedVRSQWKNLKDTFVRKLRWVHe---- 83   Cae...
Q9W1E7                   32 LIELYRSSDCLWNHYS-ELYKNKDCRAKAIESICASL--E--IT----Kh----dYGKKVHNLRNQFNAELKKLErrl-e 97   fru...
Q7K4R2                   11 LISEYRSRRGLWDMTC-DEYRKKDVKQRLLNEVSQVL--GGNIP----In----eLEKKFHTLRTQYHREISRMK----- 74   fru...
XP_001628368             28 LITLWREHEELYDLRH-VDYPKRDRRRLAFKHISEQL--G--IT----Vp----eIKKKMTNLRTYYTKEIWKERpggkm 94   sta...
XP_001625193             35 LIKLWEEENVLYNGRHkDHFRREC-RSAAMDRIQQRL--AEDGD----LlftleeLHKKMRCLRTYYSKEIKKEKisk-- 105  sta...
FlyBase:CG33017-PB       21 LIRLYRSNECLWNPKS-PGFHSGSAKDDAWRQITRRM--NCGLT----Pd----qVELQVLGLRHYYSKELAAIRn---- 85   fru...
WGS:AAAB:AGAP004174-PA   13 LIQSYKKHPVLYDMRH-PRYYNKTFRGKALSEIVDDV--QQVRPdt-sMk----dVLRKIQTMRTQFGQELTKTRr---- 80   Ano...
Q9VXQ6                  259 LIHSYQRNPFLWDHGN-AQFRDRVKRARFLDWIVLEF--KSRFNislaKd----aITRKWDNLRTVYKRECNRMA----- 326  fru...
Q29LR3                   90 LIEQYRCHTELWNRAD-PKYKDKLCRFRAWSEIAERF--G--CS----Ka----eVERKMNVLLTQYRREKHKMFv---- 152  Dro...
O80512                   72 LIDAYRDKWYALNRGN--------LKANHWEEVAEAV--GANCPdv-iLkktavqCRHKMEKLRKRYRTEIQRAR----- 135  tha...
Q9XV35                   84 -gKYMEDAMKEPTWKFYRMLTFL 105  Caenorhabditis elegans
Q9W1E7                   98 esGGDRDSEKACRWEHFKTLMFL 120  fruit fly
Q7K4R2                   75 -----RKEPYNSKWFGFKNLVFL 92   fruit fly
XP_001628368             95 gtDEPSKEPYISRWQHIHSLSFL 117  starlet sea anemone
XP_001625193            106 lnSSNPQDLYTSRWPLYHSLHFL 128  starlet sea anemone
FlyBase:CG33017-PB       86 --SQIEGYSYSPRYSYFEDLHFL 106  fruit fly
WGS:AAAB:AGAP004174-PA   81 --HSMNGSMYQPTVWWYESLSFL 101  Anopheles gambiae str. PEST
Q9VXQ6                  327 -----LEKTNISTLWYFKELHFL 344  fruit fly
Q29LR3                  153 -kIYQGIQPNPSKWYAFKRFDFM 174  Drosophila pseudoobscura
O80512                  136 ---SVPVARFISSWVHFKRMEAM 155  thale cress
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