Conserved Protein Domain Family
Dev_Cell_Death

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pfam10539: Dev_Cell_Death 
Development and cell death domain
The DCD domain is found in plant proteins involved in development and cell death. The DCD domain is an approximately 130 amino acid long stretch that contains several mostly invariable motifs. These include a FGLP and a LFL motif at the N-terminus and a PAQV and a PLxE motif towards the C-terminus of the domain. The DCD domain is present in proteins with different architectures. Some of these proteins contain additional recognisable motifs, like the KELCH repeats or the ParB domain.
Statistics
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PSSM-Id: 402253
View PSSM: pfam10539
Aligned: 50 rows
Threshold Bit Score: 157.676
Threshold Setting Gi: 303281292
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q5VQH0        22 GGVVFCCNNNTFDECFTKQLFGLPQRNILYVKNVKPGLPLFLFNYSNRQLHGIFKATSTGQLNIDRFAWmseqsnd-akt 100 Japanese rice
XP_003059938  33 GGVIFICSRETYDDTTRAGLFGLTQGSWSFVKRITPGMPLFLYNLTERRFHGVFEATSDGAMNADPTAWktsgagagdaa 112 Micromonas pusi...
EFJ09015      31 GGFIFFCNDETMPEDFERCLFGLPRSFIDSVKGIRKGLPLFLYNYSNRCLHGVFEASSDGGLNIEPDAWinkda----rs 106 Selaginella moe...
XP_004981020 182 GGYIFVCNNDTMQEDLKRQLFGLPARYRDSVRAITPGLPLFLYNYTTHQLHGVFEAASFGGSNIDPTAWedkk------- 254 foxtail millet
XP_006339276 182 GGVIFGCTVSTMNECIRNQLFGLPAPHISYVKNIDPGLPLFLFNYSNRELHGIYEAASSGRMNINPYGWtld-------- 253 potato
EEF35711      21 GGVIFGCKKNTMSECLSEQIFGLPAPHFSYVKNIDPGLPLFLFNYENKKLYGIFEAAGAGQMNINPYGWttd-------- 92  castor bean
KRH00341      35 GGIIFGCKNATMKECLSKQLFGLPAHHFCYVKNIDPGLPLFLFNYTDRKLHGIFEAASSGRMFIDPYGWttd-------- 106 soybean
XP_009400961  35 GGVIFGCKHKTMEECLSKKIFGLPSTHFVYVRNIEEGLPLFLFNYSDRKLHGIFEAASHGQLNTNSYAWtdg-------- 106 wild Malaysian ...
EEC82210      34 GAVIFGCTNNTIAECHSRQLFGLPRTHLSYVQNIKEGLPLFLFNYDDRKLYGIYEAASNGKFCPESNAWsqd-------- 105 long-grained rice
XP_009406897  27 GGTIFGCKDATMKECLKKQLFGLPSTHFSYVRNIEPGLPLFLFSYTNRTMYGIFEAACHGQMNIDPYAWten-------- 98  wild Malaysian ...
Q5VQH0       101 nakTTPFPAQVRFS--------TRTECPPLPESKYKSVIINNYRk-------DKpSHFRFELDHRQTRDLISLF 159 Japanese rice
XP_003059938 113 gidGSPYPAQVRYKhtrvtcsaSAASCKPFLRFAAGEA---------------NgKKFRLDLTPGEATRLARVF 171 Micromonas pusilla CC...
EFJ09015     107 gvdVSRYPAQVRVR--------IRENRAPLEEDAFRPVL---FH--------YEaKKFRLELSMSEVLAtly-- 159 Selaginella moellendo...
XP_004981020 255 ckgeSRFPAQVRIR--------IRKLCKPLEEDSFRPVL---HH--------YDgPKFRLELSIAETLSLLDLC 309 foxtail millet
XP_006339276 254 gsgRTEYPAQVQVR--------LRLHCRPLAESLFKPIIQENYY--------HDqRHFTFELDHVQAGNLISkf 311 potato
EEF35711      93 gsrRTQYPAQVQIR--------VRLQCHPLSEEKFKPIIADNYY---------RyHHFWFELDHAQTSKLMSLF 149 castor bean
KRH00341     107 gseRTQYPAQVQIC--------VRLKCHPLPEDKFKEVIADNYY---------ThNRFYFELDHAQTSKLISLl 163 soybean
XP_009400961 107 stkRTPYPAQVSIR--------IKTNCAPLTENQFKKIIEDNYY---------NpQHFWFELDHAQTSALIAhf 163 wild Malaysian banana
EEC82210     106 gkgKTSYPAQVAMR--------IKVWCVPLAESQFRGAILANYYqrmpgapgQKlHFFQFELDHAQTRALMDMF 171 long-grained rice
XP_009406897  99 gaqRTPFPAQVRVY--------TKTPCQPLSEKQFKSVIEDNYY---------AqKHFWFELDHAQAKGLMLLF 155 wild Malaysian banana
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