5IJO


Conserved Protein Domain Family
Nup188

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pfam10487: Nup188 
Nucleoporin subcomplex protein binding to Pom34
This is one of the many peptides that make up the nucleoporin complex (NPC), and is found across eukaryotes. The Nup188 subcomplex (Nic96p-Nup188p-Nup192p-Pom152p) is one of at least six that make up the NPC, and as such is symmetrically localized on both faces of the NPC at the nuclear end, being integrally bound to the C-terminus of Pom34p.
Statistics
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PSSM-Id: 402215
View PSSM: pfam10487
Aligned: 30 rows
Threshold Bit Score: 621.604
Threshold Setting Gi: 1752388852
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5IJO_J         31 QIEAELNKHWRRLLEGlS-YYKPP-SpSSAEKVKankdva-----------splkeLGLRISKFLGLDEeqsvqllqcyl 97  
P52593         39 QIRQFLKANKTNLIES-LnTIRQNvT-SSGDHNK----------------------LRSTIANLLQINV----------- 83   Saccharomyces...
Q6FP54         30 AVSAFLEKNKRQLLEL-Q--LGSNeS-TKHNDNNdtkriiarkil----------gydydfegsneYNLn---------- 85   [Candida] gla...
Q16YE6         19 vVRDRLMDVSKQLTDG-IlMYRKAaN-DKQSEEQlkkamker-------nqqkllaFATKLYQYLDIDAlqswnilcfyl 89   yellow fever ...
Q7Q9K3         30 DVKEKLFQVSKELVDG-IlHYKKP---TKASEEKlqklikdr-------nqlklqpFANKLHQYLDIDAvqswqilcyyl 98   Anopheles gam...
EKC37617       31 fVDRELNRNKKKIING-LsFYKKPrC-VQGEILKtkklk------------kvteeFLLKTSAFLGLDEgetyelfisyl 96   Pacific oyster
XP_015134970   29 QIASELNKHWQRLLEG-LsYYKPPsT-TSAEKIKadkdva-----------aplkeLGLRVSKFLGLDEeqsvqllqcyl 95   chicken
F6WXT2         30 QIKAELDRYGDRLLQG-LaYYRPPsT-SSTGKVKanknls-----------palqeLGLRLSKFLGLDEeqsvellqtyl 96   tropical claw...
XP_002552412   31 llSKFLKDNKPLLLEP-A-KFNEL------GAEVpskttplvigsakynisvenwkDASRLSRALNVSYeqslriv---- 98   Lachancea the...
NP_985141      42 lIAQFLKNNKSLLLNV-S-EF----L-NTENTGElsqkmtlrgs--eyeassedvkEAVVLSEKLHISPqeclrvivq-- 110  Eremothecium ...
5IJO_J         98 qedyrgtrDSVKTVLQDERQSQali--lkIADYYYEERTCILRCVLHLLTYfqd---erHPYRVEYAdcvdkLEKE---- 168 
P52593         84 --------DNDPFFAQSEDLSH-------AVEFFMSERSSRLHIVYSLLVN--------PDIDLETYsfidnDRFNvvgk 140  Saccharomyces...
Q6FP54         86 ----------------------------eFLEKELLERNSMVDIMVDLNTrrhicdryiPDLNVNNAknedsL-TGrist 136  [Candida] gla...
Q16YE6         90 vneyrgpaNALADYLSTESSMLtll--sdIWSYYSLERMVLLKVVKNLLEfyn---sgnHPYSKEYKviidkIGMAnlrk 164  yellow fever ...
Q7Q9K3         99 vneyrgaaTALAEYISTETSMVkll--hdIWTYHTLERMVQLKVMKNLLEyfh---sgtHPYSKEYRevvekMGLQalrk 173  Anopheles gam...
EKC37617       97 sndyrgskKELQQVLRNERLAHala--ykVRDYYYTERLYLLQSVKVIVNswq---nnlHPFQRGFGtfmksTEVVsg-s 170  Pacific oyster
XP_015134970   96 qedyrgtrDSLKTVLQDERQSQalm--lkLADYYYEERICILRCVLHLLTyfq---derHPYTAQYFqcvekLD-Ke--- 166  chicken
F6WXT2         97 lydyrgtqESVKGVPQDERQSQalmlkasMVDYYYEERISLLRCVLYILNyfq---ddkHPYSAEFSkcvemMEQKe--- 170  tropical claw...
XP_002552412   99 ------aqsdarSCLEKDRMFL-------YAQRILQERNAIVDAAFLILNwdc----kyVPAKEDLIstisiEKTTlcsh 161  Lachancea the...
NP_985141     111 --------cnlrlhpkEERRLL-------YAQNILQERNAVLDTILVLLNnd-----nvAQISKIYLdlfmqKKATiigd 170  Eremothecium ...
5IJO_J        169 L-VSKYRQQFEELYKTEAPTwet----------hgNLMTERQvSRWFVQCLREQSMLLEIIFLYYAYFEMAPSDLLVLT- 236 
P52593        141 L-ISIISSVIQNYDIITASSlahdyn----ndqdmFTIVSLV-QLKKFSDLKFILQILQILNLMILNTKVPVDIVNQWFl 214  Saccharomyces...
Q6FP54        137 V-IDVLLNTLTATNSVDECVlqcmdhleelhldneDTIQDII-DLIINYNILYCFKLLKLLTLYIINRNVAVSLTQKWF- 213  [Candida] gla...
Q16YE6        165 SyINQLETLINESMPGKLIPg-------------dMFNNQAKmVSWSERKLREMNEILHIILMIIHNDGISVEDFCRLF- 230  yellow fever ...
Q7Q9K3        174 SyLAQLTHLIADPPSSQKAPla-----------gdLLHGQTR-VACAERRLRETNEILQILLLIVHYSGISPEELDQLF- 240  Anopheles gam...
EKC37617      171 L-MKMLLETFEQLTQEPFPTwet----------nsILMNDRQmYLWVQENLREQSEILEILYIYVKDFDLPEEQVLKLL- 238  Pacific oyster
XP_015134970  167 L-VPNYRKQFEELYKAEAPTwet----------hgNLMTERQvSRWFVQCLREQSMLLEVIFLYYAYFEMAPDELLAFA- 234  chicken
F6WXT2        171 L-FGKYLKQFESLCREEAPTwet----------hgNFMTERQvSRWFVQRLREQAMLLEIIFLYFACFAASPSDLLALT- 238  tropical claw...
XP_002552412  162 L-ISLLSDVAANFGSldk--------------nnsIWSQPLQ-DLKDCQDVFYAIRIMELLTLLIMNSDTPVGIVSSWC- 224  Lachancea the...
NP_985141     171 L-ISLLSTICAELASMEPSA----------------EDVSIS-QFRYSHDISYLLNILRLLSILCLNSELPVPIIEEWV- 231  Eremothecium ...
5IJO_J        237 ----KMFK------------EQGfgsrqtNRHLVD--ETMDPFVDRIGYFSALILVEGMDI-----ESLHKCALDdrrel 293 
P52593        215 qyqnQFVEfcrninstdksiDTSslqlykFQNFQDlsYLSETLISRISSLFTITTILILGLnt--sIAQFDIQSP----- 287  Saccharomyces...
Q6FP54        214 ----SNFSeivnqvtlisstHSNr----rFLDNTErsMVDTLFIAKLESTISIVSIVFLGLssareDSNLNMDTD----- 280  [Candida] gla...
Q16YE6        231 ----KLFK------------GHAfgrqqqYLDSTN--ENHGDLVKRITFSELAIICEALDL-----TEKPDKTDW----- 282  yellow fever ...
Q7Q9K3        241 ----KLFR------------EHSfgkqqeHLDPGS--EIHAELVKRITYNELALVFRTLDL-----SDKFDDAGW----- 292  Anopheles gam...
EKC37617      239 ----ELFK------------RHGfgrlqnYKHVID--DSLIFLVKRIGYLEVLICVEMMDL-----EAVLACIERgsfnd 295  Pacific oyster
XP_015134970  235 ----KLFK------------EQGfgtrqtNRHLVD--ESMDHLVDRIGYFSALILVEGMEI-----DSLHERALDdrtee 291  chicken
F6WXT2        239 ----KLFK------------EQGfgcrlqNRHLVE--PSMDPLVERIGYFSVLIFLEALDI-----ETLMTCSLSdkteq 295  tropical claw...
XP_002552412  225 ----SVLK------------TTNy-----FQCFSEvaTMPREVPDKLEALATINTVLMLGFdv--sTFTIKVESP----- 276  Lachancea the...
NP_985141     232 ----DFLD------------KTEcgvdgfWQk-----NLPEEVSLRLQSLVVIVSILMFGLgt--aHHNINVSAP----- 283  Eremothecium ...
5IJO_J        294 hqFAQDGLICQDMDCLMLT-------FGDipH--HAPVLLAWALL---RHTLNPEe------------------TSSVvr 343 
P52593        288 --LYMDTETFDTVNSALENdvatnivNED--PifHPMIHYSWSFIlyyRRALQSSes---------------fdDSDItk 348  Saccharomyces...
Q6FP54        281 --FLHDVATFELVHSVLLD-------EMH--KkrMPIVLYMWSFIlcaKSIIAEDdsdeitsineldfirkcfpQDSIhs 349  [Candida] gla...
Q16YE6        283 -----AEGVIEALDNELVT-------LHQ--FpeHGPLLLMWMLFnfrIPSHLEDddvss-------------------- 328  yellow fever ...
Q7Q9K3        293 -----IERVVAALDGPMVS-------LHQ--FpeHGPLLLVWMLFnfrLQHTVEDedttr-------------------- 338  Anopheles gam...
EKC37617      296 hfLLKDKETFMKLDKVVQT-------LGS--EdsHGPLLLLWSAM---HMFGGEGsdfsl-------------------- 343  Pacific oyster
XP_015134970  292 hkLANNSHIHQEMDNQLLQ-------LGD--VshHAPVLLAWALL---RHTINPEesanv-------------------- 339  chicken
F6WXT2        296 hpFSSEEQVCKEMDSVLVT-------LGD--AphHGPVLLAWALL---RFALNADkvtpt-------------------- 343  tropical claw...
XP_002552412  277 --FFNDPECFKTVNKTLLD-------QPS-----SAIILYYWSFVlslKSYLFEEypeknak-----fldnvfgTVPVsh 337  Lachancea the...
NP_985141     284 --FFNSEQIFIKVNKLLLR-------PSS-----NPVILYYWSFVlsvKAYLLEEtsetnvd-----fiknvfgTTTIdd 344  Eremothecium ...
5IJO_J        344 ---kiGGTAIQLNVFQYLTRLLQ---SLasGGNDCTTSTACMCVYGLLSFV-LTSLElhtlg--nqqdIIDTACEVLADP 414 
P52593        349 ----fALFAESHDVLQKLNTLSE---IL--SFDPVYTTVITVFLEFSLNFI-PITAS-----------TSRVFAKIISKA 407  Saccharomyces...
Q6FP54        350 msilfAKNAEDIGLLAKFLETSN---CI--RNDNIFTTLFASFMTLSVNFI-PFTAS-----------TTKIIKSVLNDL 412  [Candida] gla...
Q16YE6        329 ryrqfGSRAIQLGVFEYLHALVTh-rTF--KDHSFVCRITRKAIYNQLAFLcQLFDSdgsva--dhakVIDLLSELISSP 403  yellow fever ...
Q7Q9K3        339 ryqqlGSRAIKLGVFEYLHAIVSh-pMF--KDQSLTARIVRKSIFNHLGFLcQLFDAdesia--hhsnIYDLLSELLTSP 413  Anopheles gam...
EKC37617      344 -arkyGNAAIHLHVFHYLYNLLMsepFN--EENSMICSVSHLTVYNLLVLIlSTFDEhtlgtdqdalaLHRVICLVLKQV 420  Pacific oyster
XP_015134970  340 -irrmGSTAIQLNVFQYLTKLLKs-lSS--GGKNCTASTACMCIYGLLSFVlTSLELhtlg---nqqdIIDAACEVLAAS 412  chicken
F6WXT2        344 -vrkmGSTAIQLHIFQYLTRMLQs-lRS--GENNCTTSTACLCVYTFLTFVlTNLEEqvlq---sqqdLVDTAFQVFAAP 416  tropical claw...
XP_002552412  338 lislmVKRSEELDVLASFTKFSG---CL--EQDKLWSVTLSSLMALSLNFI-NITPQ-----------AAKTVKELLTKN 400  Lachancea the...
NP_985141     345 lintfAARAESLHVLDGICRLHK---TL--SDEGLYSAIMCSFLILSLNFI-SLNDE-----------TTHAIKLVLTGM 407  Eremothecium ...
5IJO_J        415 --SLPELFWGT--------------------EPTsglGIILDSVCGMFPHLlspLLQLLRALVSGKSTAkkvY------- 465 
P52593        408 peQFIENFLTN--------------------DTF---EKKLSIIKAKLPLLnesLIPLINLALIDTEFA---N------- 454  Saccharomyces...
Q6FP54        413 prGVIENFISN--------------------NAF---ITKFDTIKAKLPLIdegLLPFINLTSINEELA---E------- 459  [Candida] gla...
Q16YE6        404 s--IAADFCKN----------------------------------ELNPIRslpLATIAHALASAGSNS---Ykf----- 439  yellow fever ...
Q7Q9K3        414 t--IATEFCKIe------------------dHPI---RALFNICLEHFPVEftpLSKVAYALASAGSSQ---Nky----- 462  Anopheles gam...
EKC37617      421 s--VSEDFWEKailmnlflpflkypklqgsdEGV---GSVYHSALLRFPLDyssFVQFSAALAESTPTS---Aerasllw 492  Pacific oyster
XP_015134970  413 s--IPQLFWKTep-----------------tAGL---GIILDSVCGMFPHLltpLLQLLQALVSDKSTA---Kkv----- 462  chicken
F6WXT2        417 n--LPDLFWNMep-----------------tAGL---GILLDSVVGMFPFHlspLLKLFTALVS-KSSA---Kkv----- 465  tropical claw...
XP_002552412  401 prSFVEKFLTN--------------------NEV---EKKVALLRAKVPLLeegLLPLIHFSTVHPDFA---N------- 447  Lachancea the...
NP_985141     408 pkDLIESFLTS--------------------PEL---EKKLSILRAKLPLLhesLIPMINLTSIHPEFA---H------- 454  Eremothecium ...
5IJO_J        466 ----SFLDKMSFY-NELYK--HKPHdvISHEDG--------------TLWRRQTPKLLYPL----GGQTNLRIPQGTVGQ 520 
P52593        455 ----FELKDICSFaVTKSSl-NDLD--YDLIADtitnsssssdiivpDLIELKSDLLVAPPleneNSNCLLSIPKSTKGK 527  Saccharomyces...
Q6FP54        460 ----FNWEAFGSY-AVKMPl-GSID--YDVADRsnsnd-----sstlEQIQLSSEVLVKPPfe-qDDDVLMPLPKSTKAF 525  [Candida] gla...
Q16YE6        440 --ihGLLESLPVY-SEVYNp-DNYElrSSPTNE--------------DEFVLAHD---YVPf----rRIGFKVPRGTSVV 494  yellow fever ...
Q7Q9K3        463 --iqELLENLPVY-TELYTgqNQYEirKAASSNe-------------DEFIMCHD---YTPs----sKINFTIPRGTKLI 519  Anopheles gam...
EKC37617      493 gkvfHIWKQLQRY-TEYLDc-NHSSdlTSTKEL--------------NEWKLVVN---KRPy----pTRDFILNAGTKGK 549  Pacific oyster
XP_015134970  463 ---ySFLDKMSFY-IE-LYk-HKPPdvISHEDG--------------TLWRRQAP---KLLyplgLGQTNLRIPQGTVGQ 519  chicken
F6WXT2        466 ---ySFLDRMSSY-TE-HYr-HKPHdiLSHEDE--------------TLWKRQTP---KVLyalgLGQTNLRIPQGTIGQ 522  tropical claw...
XP_002552412  448 ----FEWKELNTY-TEKLRl-SSLS--YDLADLpgpt------sessDIIVLKQELLVKPPle-sQSNVMMPIPKETRGK 512  Lachancea the...
NP_985141     455 ----FEWKELSTY-AQKLKl-NDID--YDLSVDddnr------vestDLIVLKNELLVKPPme-fEDNVMLPIAKDTKGQ 519  Eremothecium ...
5IJO_J        521 VM-------------------LDDRAy-------------LVRWEYSYSSWTLFTCEIEMLLHVVSt--------ADVIQ 560 
P52593        528 ILti----------------kQQQQQqqqqngqqppttsnLIIFLYKFNGWSLVGRILQNLLHSYMekg----tqLDDLQ 587  Saccharomyces...
Q6FP54        526 IVadvpaitsgkehtkdsivkYNSEDgssnfttnnvtnetLLVFDYQYNGWSLLGRILQNLSILYTvkg----ndINYEQ 601  [Candida] gla...
Q16YE6        495 VLd------------------KRSHT--------------MVHFRTKFNFYDALHHEINELLSdala-----ytqLNDER 537  yellow fever ...
Q7Q9K3        520 VRd-----------------lHNQRT--------------YVHFSTGYNYFNALHHEINELLEdaqa-----tstLNSER 563  Anopheles gam...
EKC37617      550 ILtm----------------gTKHDAs------------pIIQWYVTFSGWDLLLCEVETLLDQVAqgsgmvsptQ---- 597  Pacific oyster
XP_015134970  520 VM-------------------LDDRAy-------------LVRWEYSYSSWTLFTCEIEMLLHVVSta-----dvIQ--H 560  chicken
F6WXT2        523 VM-------------------ADEHGf-------------LVRWEYSYSCWTLFTCEIEMLLHVVSta-----dvIH--Q 563  tropical claw...
XP_002552412  513 IIpi----------------tSTAED--------------AVVFMHDYNGWSLLGRILQNICDTYTqse---edeAKREK 559  Lachancea the...
NP_985141     520 IIps----------------aTGDED--------------VVVFLYKYSGWALIGRILQNICETYRdsc---aptTARLR 566  Eremothecium ...
5IJO_J        561 hCQRVKPIIDLVHKVIsTDLSIADCL-L-------------------PITSRIYMLLQRltTVISPPVDVIASCVNCLTV 620 
P52593        588 -HELMISIIKLVTNVVdPKTSIEKSS-EilsylsnsldtsastingaSIIQVIFEIFEI--SLQRKDYTSIVQCCEFMTM 663  Saccharomyces...
Q6FP54        602 -KEFMIAAISLLSNIMsSTIPVDHSI-Kileslssq----lskprddDIISVVFKIFER--ALHKRNYELLCICASFTNV 673  [Candida] gla...
Q16YE6        538 -IQRIMAGIRYLAVAVkRVNQPHEISsEm-----------------vHPTEMVFDILLKfkVVQNPPVELLAECINVCAA 599  yellow fever ...
Q7Q9K3        564 -VQRIATGLKYLAVAVrRIQQPHDITaEm-----------------vHPTEMVFDVLLKfrAVPNPPVDLLVQCLNVCTA 625  Anopheles gam...
EKC37617      598 -IEKVTDAVELVHAVLkNHPHSEKDF-Q-------------------PIIHCIYSLIHRfvRLSHPPILLIVQCIECVTC 656  Pacific oyster
XP_015134970  561 -CQRVKPIIDLVHKVIsTDVSVADCL-L-------------------PITSRIYMLLQRltTVISPPMDVIASCVNCLTV 619  chicken
F6WXT2        564 -CQRVKPIIDLVHKVIsTDLSIADCL-L-------------------PITSRIYMLLQRltTVMNPPMDFLSSCVDCLAA 622  tropical claw...
XP_002552412  560 -SELAVAIIDLVANTMgAETPIERST-Eilqhls-------gyveddDIISVLFKLFEL--ALHSRNLPIINAGLNLMIE 628  Lachancea the...
NP_985141     567 -QYLLVSILDLISSIVdADTPLERST-Eilqhis-------gyvtedDIISLIFRTFEQ--ALHSRDMEVLVPCLKLFTS 635  Eremothecium ...
5IJO_J        621 LAARNPAKVWTDLRHTGFLPFVAhpvsslsqmisaegmN---------------AGGYGNLLMNSEQPQGEYGVTIAFLR 685 
P52593        664 LTPNYLHLVSSYLNKSDLLDKYG---------------K---------------TGLSNMILGSVELSTGDYTFTIQLLK 713  Saccharomyces...
Q6FP54        674 LVRRFPHFVWAYLSTSDLLDHYG---------------K---------------SGLVNIILGSIELTNGEYDFTISIAK 723  [Candida] gla...
Q16YE6        600 LVPLFEPEIYARVINLNILPTVN---------------NanldfkdyaagtsfeSSLIGFYLVNCEKNAGKYRILLAYLN 664  yellow fever ...
Q7Q9K3        626 LVPLFEQEIYTRIINLNILPSVN---------------NanltyqdyangvgydSSLIGYYLMNVERNAGRYPILMAYFN 690  Anopheles gam...
EKC37617      657 LAKQNPVKVWHNMKQTGLLPYLT---------------EnidniseilsgqglmAGCYGNMLFGVECIEGSYPITTAVLE 721  Pacific oyster
XP_015134970  620 LAARMPAKVWTDLHHTGFLPFVA---------------NpvssmnhmisaegmnAGGYGNLLMSIEQPQGEYSVTISFLN 684  chicken
F6WXT2        623 LATRMPAKVWIDLRHTGFLPFAA---------------Npvsghii--stegmnAGGYGSLF-GIEQSQGEYSITLSFLR 684  tropical claw...
XP_002552412  629 LTPNFSHFVWTHLARSYLIDRNG---------------K---------------EGLAISILGNIERTSGVFQSSILLIK 678  Lachancea the...
NP_985141     636 MVTNFPHIVWSHLSRSDLIDRHG---------------K---------------AGMVTTLIGALELPNGEYLFTIAFIK 685  Eremothecium ...
5IJO_J        686 LITTLVKG----------QLGSTQSQGLVPCVMFVLKEMLPSYHKWRYN-SHGVREQIGCLILELIHAILNLCHETdl-- 752 
P52593        714 LTKVFIREslsl---kniHISKRSKIDIINKLILHAIHIFESYYNWKYN-NFLQKFEIAFHLTLIFYDVLHDVFTI---- 785  Saccharomyces...
Q6FP54        724 MTVGLIDDavttslysdsGVPLKTKKSILSNLIVHLLNVYESFQFWKYSkSIEQRFELSLELTKAFSKILYFVHGIds-- 801  [Candida] gla...
Q16YE6        665 FLKTYTKLgk------snIFGVE-----LPGLIFLLREVFPHAHTWRFE-NEAERQKVYVLIMQYLFEILQLSPEMlknd 732  yellow fever ...
Q7Q9K3        691 FLKTYTKLgr------dnVFGVE-----LPGAIFLLREVLPYANNWRFE-TSSDRYRVLVFVVQYIYEILQLSEDKlesd 758  Anopheles gam...
EKC37617      722 FISNIIEP----------FFKDSMESELMASFMYILREIFPVFQKWRFY-KLKTRELIGRKCVEIFHKTLENVINrsk-- 788  Pacific oyster
XP_015134970  685 LITTLVRG----------QLGSTQSQGLVPCIVFVLKEMLPNYHKWRYN-SHGVREKIGCLILQLIHAILNLCPEmdp-- 751  chicken
F6WXT2        685 LVTTLVKG----------QLGSTQSQGLVPCILFVLREMLPNYHRWRYN-SHGVREQLGFQILSLIHAILNLSPEeee-- 751  tropical claw...
XP_002552412  679 LASCLVSEslt----atdIFPERMKKEILGHLMAHLINIYEGFQFQTYT-MQWQYLEIGLQLTSLISKVLFAVYGVdf-- 751  Lachancea the...
NP_985141     686 LADELVSEslh----vetAFPERMKRELLGRIVKQLLHVYESYQYWKYS-NINQRFEIGALLTSLFTKIIYSVYGIdq-- 758  Eremothecium ...
5IJO_J        753 -hsS------HTPSLQFLCICSLAYTE------AGQTVINIMGIGVD-TIDMVMaaqprsdgaEGQGQ-------GQLLI 811 
P52593        786 ---NphqkdqLIISSSANKLLQLFLTPmdsidlAPNTLTNILISPLN-TTTKIL---------GDKIL-------GNLYS 845  Saccharomyces...
Q6FP54        802 -etPpenkitNVLSKAADTITNAFLVPdsydppVVISLINTITSPKN-KTIYIF---------GNGLF-------DELYD 863  [Candida] gla...
Q16YE6        733 yprT---------VLQNVCVYSLLDLD------NGLTLLKFVGVGNG-YLQSIM---------ENETSwmm--aqEQSMN 785  yellow fever ...
Q7Q9K3        759 yarR---------VLRDACVYSLLNRD------NGMVLLKIVGLGNG-YLQAVM---------ERESNwml--vpEQQLN 811  Anopheles gam...
EKC37617      789 -pvEsts---krPKVQEVVVYSLLFTE------AGQTLLGIIATGSD-NVDQAL---------VQQGSmae-ggiGAEMI 847  Pacific oyster
XP_015134970  752 -------rssNAPSLQSLCIFSLANTE------AGQAVINIMGIGVD-TIDMVM---------ASQSSsdesqgqGQLLI 808  chicken
F6WXT2        752 --------stSTPNLQSLCIFSLTNTE------AGQAVINIMGVGVD-TLNAVM---------LTQAGssgtegqGQMLM 807  tropical claw...
XP_002552412  752 -ttSpskkvtGVLADAAQIAVGAFLGAstsemrAANSLITIVTFAKN-TNVPLH---------RGLPF-------GEMRH 813  Lachancea the...
NP_985141     759 -dsKpgdkitRVLADAASFIVTVFIGTdspdirAVNSLVSVLVSPTTlEAISLN---------HGVN--------GAQYN 820  Eremothecium ...
5IJO_J        812 KTVKLAFSVTNNVIRLKPPSN-----VV-SPLEQALSQHGAhgnN-----LIAVLA--KYIYHKHDpalprlAIQLLKRL 878 
P52593        846 KVMNNSFKLCTLLIAIRGSNRd----LKpSNLEKLLFINSS---K-----LVDVYTlpSYVHFKVQ------IIELLSYL 907  Saccharomyces...
Q6FP54        864 HVVQKAYDLANLLVSIRGVSK-----LNaSSLERMLFCQSP---K-----LIDIYL--TKPTLKIS------IVKLLNSL 922  [Candida] gla...
Q16YE6        786 QLVQLSMTILMQILRLKRTVIedekmLS--PLESAIYTQPK---QrdtlrIIPVVT--GYMNNIFNrrlpilSCRLLRRF 858  yellow fever ...
Q7Q9K3        812 LMIQHSMTILMQILRLKRHIHey--dLS--PLESAIYTQPK---QrdtlrIIPMVT--GYMSNIFNprlpilSCRLLRRF 882  Anopheles gam...
EKC37617      848 RLIQISFSVLNQLLLLKSPDLpl------sPVESALSSQPV---VrqnqhIVATIA--QYIYHKHNprlpmlACLLLKRL 916  Pacific oyster
XP_015134970  809 QTVKLAFSVTNNVIRLKPPSSvv------sPLEQALTQH-----GahgnnLIAVLA--KYIYHKHDpalprlAIQLLKRL 875  chicken
F6WXT2        808 QTIKLAFSITNNVIRLKPLSSai------sPLEHALTQH-----GahgnnLIAVLA--KYIYHKYDpslprlAIQLLKRL 874  tropical claw...
XP_002552412  814 SLIDQSFELANLLISVRSLLH-----LPpSSLERSFFIHSA---T-----LVDIYA--SHLGLRVE------VIKLLTHL 872  Lachancea the...
NP_985141     821 ELLQKSFAFGNMLISVRGLLK-----LPpTTLEKSIYSKAT---D-----LVDAYI--YKPSLKVH------VIKLFTYL 879  Eremothecium ...
5IJO_J        879 AtVAPM-----SVYACLGNDAA-AIRDAFLTRLQSKIEDMRIKVMILEFLTVAVE-TQPGLIELFLNLEV 941 
P52593        908 V-EAPWnddypFLLSFLGEAKSmAFLKEVLSDLSSPVQDWNLLRSLYIFFTTLLEsKQDGLSILFLTGQF 976  Saccharomyces cerevisia...
Q6FP54        923 V-GVPWsseypFLYSYLGHTYSeKFLSSIIKDLTTTLQDYQLAKTLYVFFGTLIRsKQDGLSILFLTGRA 991  [Candida] glabrata
Q16YE6        859 SiEFKM-----SLLACLDIEPD-QIRLIFLQRLRDDLESDNLKIAVLEFVEACIH-KQPGLTEAFFKvhy 921  yellow fever mosquito
Q7Q9K3        883 AiEFRM-----SLLACLDMEPD-QIRHTFLERLHDEIESDDLKLAVLEFVESCVH-KQPGLTEAFFKvny 945  Anopheles gambiae str. ...
EKC37617      917 AlVTKM-----SILSCFGGAAE-SVRDMYLNRLQGATEDLKLKVSILEFLSVCVE-AQPGLIEMFLNVQL 979  Pacific oyster
XP_015134970  876 AtVAPM-----SVYACLGSDAA-AIRDAFLTRLQSKIEDMRIKVMILEFLTVAVE-TQPGLIELFLNLEV 938  chicken
F6WXT2        875 AmVAPM-----SVYACLGSDAA-AIRDAFLSRLRDNIEDMQIKIMILEFLTVAVE-TQPGLIELFLNLEV 937  tropical clawed frog
XP_002552412  873 V-RAPFdtdapSLLAYLGDDHSkMLLNCIAYDLKAPLLNQKLSKSLYSFFSAIMEgKQDGLAILFLTGKl 941  Lachancea thermotoleran...
NP_985141     880 V-RAPWfaerpSLLAHLGHAHAkSLLELLTFDLSSPIQDYRVLKNIYSFFSSIMEgKQDGMSILFLTGNI 948  Eremothecium gossypii A...
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