Conserved Protein Domain Family
DUF2451

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pfam10474: DUF2451 
Protein of unknown function C-terminus (DUF2451)
This protein is found in eukaryotes but its function is not known. The C-terminal part of some members is DUF2450.
Statistics
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PSSM-Id: 402207
View PSSM: pfam10474
Aligned: 40 rows
Threshold Bit Score: 172.764
Threshold Setting Gi: 829101549
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:OSTLU_50546   81 LYGLKERGIALESLSRVADEFKR-IKARVKRSLPLKDAALADRFYSHTVAAVD-DLREHVY-KNVASLLLNIEfcaeaig 157  Ostreococc...
XP_002973894     726 FFAIKERTVAAESLIFLATLIRN-SRQHLQSLLHQNALPFVDQFFARTVDASI-DLREHVY-KTGARLLLNIG------- 795  Selaginell...
ERM98768         822 SFGLKERCIGPETLSHVAQILYR-SKAHLQSMLQQNNGAIVEDFYRNMVDSVL-DLVEHIH-RTTARLLLNIN------- 891  Amborella ...
XP_006591098     893 SLGLKERCVAVDTISLVARILNR-SKAHLQSMLLQSNSTILEDFYVHLVDAVP-DLTEHVH-RTTVRLLLHIN------- 962  soybean
Q8RXC2           889 SFSLKERCAAVDTVSLVARVLHK-SKAHLQSMLMSRNGSLVEDFFGQLVGSVP-DLTEHLH-RTTARILLHVN------- 958  thale cress
XP_002952743     938 QWGLRERVVAVESLIYMAQELKA-AKQAIILALPGRCQRDVEQYFNRTVEAAA-DLREYLF-KAAARVMMQGVwdg---- 1010 Volvox car...
EFC50374         667 LFGLYERSIAAESLTFLYNAVEKiIEKRMEELIPKNKRSNASQFLKSMKSATE-EVKDCIYgRTVKYLLFDFPym----- 740  Naegleria ...
EAY05740         562 LRTLDQASAASDNMKGVAWYLRS-VRSFIEESLPENSLGALRRFFSDVVSIFLqSFASFCF-PFFGPSMVNLT------- 632  Trichomona...
XP_002906666     793 LYALAERSIACEAIVGQSRLLNA-IEDLARSYLPDRYLCLMDEVFERNRTMAR-ELRSFMY-STIAVRLVDVP------- 862  Phytophtho...
XP_001019529     815 FKGISERIIAIESFDYLLFIYRS-LIPIIQYMYDKTFDQFEVDYYESIYN----ELKSLIF-VDYAPQFARSD------- 881  Tetrahymen...
jgi:OSTLU_50546  158 dgdpnfALVNSTFVGKYNIRET-PSRHNKWVDDVQAELLQFTTKLAC---ADVAPEALDVLWQHAASVIQDSLVDGFSKV 233  Ostreococc...
XP_002973894     796 ------SYVDRISNTRWELKEL-GMEHNGYVDSLLGEFKQYTVRLSN---AGVSRQVHELLLQYGVDILAETLVEGLSRV 865  Selaginell...
ERM98768         892 ------GYVDRVANAKWEFKEL-GLEHNGYVDLLLGEFKHYKMRLAH---AGIRKEIQDVLLEYGLENVAETLIEGLSRV 961  Amborella ...
XP_006591098     963 ------GYVERVANCKWEVKEL-GMEHNGYVDLMLGEFKHYKTRLAH---GGIRKEVQDLLLDYGLEIVAETLVEGLSRV 1032 soybean
Q8RXC2           959 ------GYVDRIANSKWEIKEL-GMEHNGYVDLMLGEFKHYKTRLAH---GGIPQEVQNLLLEYGVEIFAEMLVEGLSRI 1028 thale cress
XP_002952743    1011 ----drGIPAAIGVTNYNVREP-AIKQSPWADFSVRALHTFREKVLA---ARLPLPLVVLLWDFAVAVVTEGLLTGLAGV 1082 Volvox car...
EFC50374         741 -----eKYPDKIANCKYHIQVM-GDQCNKFVFELRDDIKKFFSIKLQtiddrLPENSINCLWDLAVKYVIDVLVEGFSRV 814  Naegleria ...
EAY05740         633 ------EFDTQVKNTKWTINEP-PLDPHPFTKLWTENVSSFVKQVDE---MKLAQDHKDEILTSLWNYSSFSFINDLATI 702  Trichomona...
XP_002906666     863 ------ALMESVAAVSWDIPYI-SDQHNEYIVHLVQKCGEAWGGLQIladGSIPMDAREDIWAEMVQIIMDTLLQAFSTV 935  Phytophtho...
XP_001019529     882 ------QIFSAIPNSKWELSSQeVGQTSNYVERFCQIIVDYKEQLRStggGSVPEQVQEEIFCLLIDFCYKELIEAYSKI 955  Tetrahymen...
jgi:OSTLU_50546  234 KKCTDAGRALMALDVETLRGEFAKLAPS------QSlAF-DWRYVSTYINAFY-VPEKDVEKWMQIHp-EFSKKQKLALV 304  Ostreococc...
XP_002973894     866 RRCNNEGRAVMSLDLQVLINGLQHLAPA------KL-KA-NLQIVDAYIKAFY-LPETEYLYWAKSHp-EYSKQQIINLI 935  Selaginell...
ERM98768         962 KRCTNEGRALMSLDLQVLINGLQHFVSI------NV-KP-KMHIVESFIKAYY-LPETEYVHWARSHp-EYSKNQVIGLV 1031 Amborella ...
XP_006591098    1033 KRCSDEGRALMSLDLQVLINGLHHFVSL------NV-KP-KLQMVETFIKAYY-LPETEYVHWARAHp-EYSKSQVVGLV 1102 soybean
Q8RXC2          1029 KRCTDEGRVLMSLDLQVLINGLQHFVPT------KV-KP-KLQIVETFIKAYY-LPETEYVHWARAHp-EYTKAQVVGLV 1098 thale cress
XP_002952743    1083 RKCSLEGRANMSFDLSHVERQIRAMGPP------NF-KPtALAIVDAYIKAFY-LPWEELPHWCRTHvaQYGKQRLFTLV 1154 Volvox car...
EFC50374         815 KKCNNEGRVLMQLDLQTFTTELQRMVPSslieknKGsVP-HVAIARSYIQAYYeQNESDLLEWVKKNvhHFTVKQMAAIA 893  Naegleria ...
EAY05740         703 QKVTAEGRTAMLSDFRNMAHDYVNVT--------KKrIQpDNSWVAGFVQAYF-LGIEDFKKWAVENakRYTQNHMMSIV 773  Trichomona...
XP_002906666     936 SKPTAQGRALMLLDLHALQNGLDLINHVs----sRT-VPrGREYVGNYIKAFY-YDEDELLEWVQANktLYSKVQFANLL 1009 Phytophtho...
XP_001019529     956 KKINEFGRLQMQRDFQMIQKKVQSLSKN------QTrEQlQRAFVEAYLKICQsQDIEEVQTFINTNkeRYSLEALIGLI 1029 Tetrahymen...
jgi:OSTLU_50546  305 AHN--ASAdrdrrwTAKFRQDLLNAIE 329  Ostreococcus lucimarinus CCE9901
XP_002973894     936 NLV--ASMnn---wKRKTRTDLLERIE 957  Selaginella moellendorffii
ERM98768        1032 NLV--ASMnn---wKRKTRLEMLEKIE 1053 Amborella trichopoda
XP_006591098    1103 NLV--ATMkg---wKRKTRLDILEKIE 1124 soybean
Q8RXC2          1099 NLV--ATMkg---wKRKTRLEVIEKIE 1120 thale cress
XP_002952743    1155 EVS--AEFnk---vKRHQKNEVLEMIE 1176 Volvox carteri f. nagariensis
EFC50374         894 TLNfgANL------KKNELKQLTSQVE 914  Naegleria gruberi
EAY05740         774 ETGfsDNI------KRQDRKDLSNFVK 794  Trichomonas vaginalis G3
XP_002906666    1010 KNGigSTL------EIKKLREIVLKID 1030 Phytophthora infestans T30-4
XP_001019529    1030 RISaaGSNiv---vKTKQKDQILTILN 1053 Tetrahymena thermophila SB210
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