Conserved Protein Domain Family
TCO89

?
pfam10452: TCO89 
TORC1 subunit TCO89
TC089 is a component of the TORC1 complex. TORC1 is responsible for a wide range of rapamycin-sensitive cellular activities.
Statistics
?
PSSM-Id: 371063
View PSSM: pfam10452
Aligned: 4 rows
Threshold Bit Score: 343.274
Threshold Setting Gi: 74582444
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
XP_001647286  42 RQFSTRSRTK---SSASFKG---LNRYYSSDGTFDPEiSGSTKHGSLKKCKSSDILYKRRTCSGLNMTSISGkkghentg 115 Vanderwaltozyma...
Q6FX06        30 RQFSTKSKAK---GSASFKG---LRRVLTHDGTFEGD-GLLNRHGSFKKSKSSDALYRRRAISGLNMTALVGekptnrvs 102 [Candida] glabrata
O74428        32 RNFIVNSRLKrggGHVRVNRsgrLGSVTMRPSALTRAhSQNPNSSLVNNSSAVSHLTKQRSLNDLHELN----------- 100 Schizosaccharom...
Q6CMN6        32 KQFSAKSRSK---SNTSFKNlqkLHKVGSHD-ALNRG-----LFDPMKKSKSSDSLNRRTVHSGLSMTALVR-------- 94  Kluyveromyces l...
XP_001647286 116 esrwntVIDGPLS------------------FGGGGLKPRRGKSTHSVLELHDADEARDDDSTTDEEVEYFTEEdeeQAQ 177 Vanderwaltozyma...
Q6FX06       103 rsqgnsRLSSPIQslskshsssnvahslasaIGGSGLRPRRTRSTHSVLTLRQGQEFYDNESTTDEEVEHFTDE---EAQ 179 [Candida] glabrata
O74428       101 ---------GPKH------------------VAKNGLIPLTQRKPNCVWD----DAPVDNDSTAGN-------------- 135 Schizosaccharom...
Q6CMN6        95 ------TSSHPVVlhqn-----------shsMKHKGLISDRNSKS-VILDLHDSG---DNDSMTDEEVESFTDIegdDAS 153 Kluyveromyces l...
XP_001647286 178 KQkmesqmDKSNQSQLGNPRNER-FPEGEMVKNNIPAESKLLRKDSdvlaETNNDApllrdrnrDNSNTKLTnqlsykpp 256 Vanderwaltozyma...
Q6FX06       180 NS------DSSDNIHHTRPKSSRmFSDDRVRDQQLSVIQSSPEDIItlngNPNQGK--------GDSYSTLR-------- 237 [Candida] glabrata
O74428       136 ----------------------------------------------------------------LDSDSALP-------- 143 Schizosaccharom...
Q6CMN6       154 DD------ETINGTGKNSTTQRNsMHSINDFQDRAGLRVDSGRPLQ----RPLSYKppsrlrnrVDADDDHIssravspm 223 Kluyveromyces l...
XP_001647286 257 SH-MIKP----------------------SNSRSSDFNKSASSQDIKANDNDENFINNde-----------------iND 296 Vanderwaltozyma...
Q6FX06       238 AHnSIDH----------------------SKNTNKDFDGNSSDDKIEAMLDDVHLSKA--------------------SN 275 [Candida] glabrata
O74428       144 -----TP----------------------SVTTNEAADSSRASSPVTRVVA----------------------------- 167 Schizosaccharom...
Q6CMN6       224 DNdKIDApdreddlidpgnqdtisntnslRRHRQHMFDFNNGNGNLQKSYNVETTEHEdiiaantavdegvrryteedII 303 Kluyveromyces l...
XP_001647286 297 DDIIDDDIIDDvGEDHIDAVTSPSdlIETEAHSLKRQGKHSSQLNALQKENNKveVVDEN-----IISNEHYVKPEdg-- 369 Vanderwaltozyma...
Q6FX06       276 KSIDHLNVKDD-HEDHIGEVDPNS--LSFDSHSLVRQERKPRTLAKVTEGEES--IADDMnknrsPIEEFTKKDREyqsk 350 [Candida] glabrata
O74428       168 ---VHDNKKKIiNSNISNAPPFNNtdVQASARPPAAGQDDSAADASTTK------------------------------- 213 Schizosaccharom...
Q6CMN6       304 DGITHTATNEKaNEDIGSDDPKRYsfAKAGAVTDEQFPEDPHSNDSSSSSKNGnmIPDSNntalnGSNIDSETQGT---- 379 Kluyveromyces l...
XP_001647286 370 htDQYVPDMILSQSTGVERHFENQLSMSNTLGAndynqineq----geipkevlMKMENRESMK--KNNGANELQFNTIR 443 Vanderwaltozyma...
Q6FX06       351 sdEPYIPDMILSQSTGVERKFENPSSIQNSLAKeiqntkyledsdnttdapskpIKNISGFDKDeiENARLNDTKHSMLN 430 [Candida] glabrata
O74428       214 --SSPVHNEVMAEP--LPHSNNREVTQATNQPkwqih------------------------------------------- 246 Schizosaccharom...
Q6CMN6       380 --EQYVPDMILSQSTGMERRFDQ-LSRQSSLAW---------------------LDPAENNNDKslKIQNTKSNKFNYIN 435 Kluyveromyces l...
XP_001647286 444 EQQNQNlqssrpks--------------nsnfsnsiSSLTNNLQRGTPEGYYGGSKFNKSSMKSASQNSLEAhnervpsk 509 Vanderwaltozyma...
Q6FX06       431 QQVNAK------------------------------SELTNNLQKVNPDNNPPRSSLTNTIFQKSRNQYASRtdtte--- 477 [Candida] glabrata
O74428       247 -------------------------------sgsdiASEPPTLSRGNSLSLLANRKVPSTNVKK---------------- 279 Schizosaccharom...
Q6CMN6       436 QDLAASlkndnidqpspprhqeqqpkqskadfstaiSSLTSHLTR--PVSRDHLLRANTVSQSRPRQQSLYR-------- 505 Kluyveromyces l...
XP_001647286 510 hneslLSQAPQTRQNNTSLNNFAQFLKSDGMDGDSRTQRKLWLQRENSIMDLNLQN-DHSHAVFMASNIEVKREFERISH 588 Vanderwaltozyma...
Q6FX06       478 kgptsLLKTDRDSNSTTKINNFSQFLKSENIDGNSRTQRKMLLQRESSILDLNSQT-DSAEAIFMTGHIEQKREYEKITH 556 [Candida] glabrata
O74428       280 --------------SQAELYDLGS--------STSRTQQKLLIQRASSKFDIVEDDmDTNPSKRF-SNPHTKHIMDLVRT 336 Schizosaccharom...
Q6CMN6       506 -----QPSYSENDTSGNGMTDFSSFLQYGDVGTDSRTQQKLWLQRENSIQDLSSQN-TSPDAVFLASNVEVRREFERISR 579 Kluyveromyces l...
XP_001647286 589 EYTSVRRFYNPIREALTRVS------STQRHHYNNGSHSQSLNadlgeilfsNYGEQTKSVNELTNSSTQAKLNRVLANI 662 Vanderwaltozyma...
Q6FX06       557 EYTTLRRYTNPLDKSLLRLKnsknsgKTNSTYGNSGLEGSSIS---------TYSNQVKELDDFLPKAQQSKLNSILASI 627 [Candida] glabrata
O74428       337 QYRNVLRTRELIPEFLEKIRss--ysNNQNFDSQNAFNTSAAG-------------TAGTREETISNGQN--------GI 393 Schizosaccharom...
Q6CMN6       580 EYTNVRRFSNPLADSLSRISqqqsieIQKQKKISTGENAGSff--------gVDYDKGKSSKETNSTANKLEMQRMLTKL 651 Kluyveromyces l...
XP_001647286 663 WKEETANFNKDTNPL 677 Vanderwaltozyma polyspora DSM 70294
Q6FX06       628 WRSESQSFNKDVNPL 642 [Candida] glabrata
O74428       394 VASAETSKKDDGVQS 408 Schizosaccharomyces pombe 972h-
Q6CMN6       652 WNSNTLEFNKDENPL 666 Kluyveromyces lactis
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap