2Z5B


Conserved Protein Domain Family
POC3_POC4

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pfam10448: POC3_POC4 
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20S proteasome chaperone assembly proteins 3 and 4
This family contains chaperones of the 20S proteasome which function in early 20S proteasome assembly. The structures of two of the proteins in this family (POC3 and POC4) have been solved, and they closely resemble those of the mammalian proteasome assembling chaperone PAC3, although there is little sequence similarity between them.
Statistics
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PSSM-Id: 402192
View PSSM: pfam10448
Aligned: 17 rows
Threshold Bit Score: 40.8817
Threshold Setting Gi: 126134155
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2Z5B_A         4 MLVKTISRTIESESGfl----------------qpTLDVIATLP---ADDRSKKIPISLVVGFKQEASLNSSSS------ 58  baker's yeast
EDO17157       1 MSVQTFSKTLEPSGSis----------------gkLLDVSVTIP---VDLSNNKIPITVTIGSKEGGINAGENDtgndin 61  Vanderwaltozyma...
Q6FJZ1         1 MSQIVVD----------------------------GLSVRVDCD----VEDGVKSPISLNLCLSGDEELKSSR------- 41  [Candida] glabrata
XP_001383602   1 MIHRSR----EVNVD--------------------GVDCVVVASy--SQSDSSRTPVTVYVNELNNAAMGD--------- 45  Scheffersomyces...
EDK36897       1 MQVARIKSPKQNLNSfalektvmntttaisklalfSGDYDVAITgcaARTSQHYPPIAVFITDVAAPRFGS--------- 71  Meyerozyma guil...
Q6BTU4         1 MIVTK-----QENIN--------------------GDDYQIVIS----IDKHDKSSINVYVNEMTNTSVGS--------- 42  Debaryomyces ha...
Q75BZ6         1 MTQTKTADYTVSTLG--------------------GDDVRLLVTmpvELTASKKVPVSIVVSGRCDGVNEE--------- 51  Eremothecium go...
XP_001387161   1 MT--EIQKDSTGLSSafsa------------yykdDRSTEIFFH---KIEYADRMVLNIQFNGVMDTTFEIPISsr---- 59  Scheffersomyces...
EDK45431       1 MSNQLICVDPSGLSKsftvnlgstankekeekkegEEEVSFHFH---LLEFANKVIINISIDGILDSSFRAPVPtr---- 73  Lodderomyces el...
XP_716296      1 MTTKLI-QDPTGFSKsfettyp-------ndtsssSSTNEFFFH---IINYSDKQILNISINGLMDTTFELPVStk---- 65  Candida albican...
2Z5B_A        59 ---LSCYYYAIplmr------drhiNLKSGGSNVVGIPLLDTKDDRIR-DM-ARHMATIISERFNRPC-YVTWSSLPSEd 126 baker's yeast
EDO17157      62 nlkLLCYYYSI--------------SRRSDKNDVVSTVLLDTSIDSVR-DT-TRQLSTLLCKKYRHPC-YVAWSSDASN- 123 Vanderwaltozyma...
Q6FJZ1        42 ---LECYYYTI----------------MGRKDDVLGIPLRDTSSDWIR-DL-ARLCATMITKKYNKPC-YVTISTVGEN- 98  [Candida] glabrata
XP_001383602  46 ------YVYAI--------------------GQSQTFLHHGTSSESGSgSGsIESLNLLLNKKLQRPV-YLNVSGA---- 94  Scheffersomyces...
EDK36897      72 ------YVYTI---------------GDRKSGETFATVIHESDADT---EEmCRNMGRVLAKKFEVPV-YTNINGR---- 122 Meyerozyma guil...
Q6BTU4        43 ------YVYSI---------------NDKKSGQIYSSVLQDHSSNIVT-EQ-ARNLGYLVVKKYCRPS-YTNINGQ---- 94  Debaryomyces ha...
Q75BZ6        52 ---LAATVYGV----------------PYKGSDVVTSVLLDTADNRIR-DF-GSTFCRVLVKKVGLPC-YVSVSSSVGR- 108 Eremothecium go...
XP_001387161  60 --aTINYSAAL--------------SNSDSDLGVEPVLLVGNHANMKI-SIvAAQIGKLILASANPKSaILSIGSKWFGk 122 Scheffersomyces...
EDK45431      74 --kVMNYESRIdldddneeeekndgSMGFVDTSGELELIVGNYSNMKI-SIvAAQVAKLV-QTKKPKEtIVTIGSRWFGn 149 Lodderomyces el...
XP_716296     66 --sAITYASALeipidqfddeheqeEIREREVIPEPILLIGDHSNMKL-SIvATQISKLI-SNNCPKPtILSIGSKWFGk 141 Candida albican...
2Z5B_A       127 PSMLVANHLYILKKCLDLLK 146 baker's yeast
EDO17157     124 -TNDMFDQISIIKTCVQYIH 142 Vanderwaltozyma polyspora DSM 70294
Q6FJZ1        99 --NFQASTIPLLAAVKEHVA 116 [Candida] glabrata
XP_001383602  95 ---AQVSTVSMFRAIVEVID 111 Scheffersomyces stipitis CBS 6054
EDK36897     123 --LDPGSYQELLNHVIDRAS 140 Meyerozyma guilliermondii ATCC 6260
Q6BTU4        95 ----ISDYPQVLKVVFNLLD 110 Debaryomyces hansenii
Q75BZ6       109 -MLDSGDQLAVIRKALEHLT 127 Eremothecium gossypii
XP_001387161 123 GDETEDSDFEKLMFILENTK 142 Scheffersomyces stipitis CBS 6054
EDK45431     150 GEEVEDSDFERLMFVLENVK 169 Lodderomyces elongisporus NRRL YB-4239
XP_716296    142 GDEVDDNDFEKLMFILANVK 161 Candida albicans SC5314
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