Conserved Protein Domain Family
DUF2457

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pfam10446: DUF2457 
Protein of unknown function (DUF2457)
This is a family of uncharacterized proteins.
Statistics
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PSSM-Id: 402190
View PSSM: pfam10446
Aligned: 45 rows
Threshold Bit Score: 362.779
Threshold Setting Gi: 291179386
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ERS97169          349 RFHEFASDLPMEDDWIRRDKAAvLQRLTINDTLKKELAIRLLGKEAEEEAEQEEndeende-----endvadDDDEEDDE 423 Sporothrix...
EFQ27011          276 RFHEFASDIPREEDWIRQAFSSqGRRITINDTLQKENAIRKLATEAEEEAEQEEedma-----------ledDEDLDNMD 344 Colletotri...
XP_003710656      255 RFHEFASDEVQDDDWIRQDKANqRRKLTIDDTLVKELAIRKLGKEAEEEAEQEEaed------------danDDEAADDL 322 Pyriculari...
Q7RYS7            279 RFHEFASDEPQEEDWIREDLTF-KPKLTIDDTLKKELAIRKIGKEAEEEAELEEamqsgeareddeeeaggdEDEEDDNE 357 Neurospora...
CAP68477          276 hFHEFASETPQEDDWIRHDDVH-KPKLTIQDTLQKEMEIRKLGKEAEEEAEAEEeeld-----------eevDEDEDGEE 343 Podospora ...
jgi:MYCTH_2304224 276 RFHEFASDEPQEDDWIRRDHSSmQPKLTIDDTLKMENAIRKLGKEAEEEAELEEeldeeedee-vdeadlidDDDEEDDD 354 Thermothel...
Q2HA56            282 RFHEFASGEPQEDDWMRRDPTSlKPKLTIDDTLVKENAIRKLGKEAEEEAELEEdeiddeedeevddadlidDEDEDDED 361 Chaetomium...
jgi:THITE_2119495 284 RFHEFASDEPQEDDWIRRDDSSmKPKLTIDDTLTKENAIRKLGKEAEEEAELEEeideeqdee-vdeadlidDEDAGDDF 362 Thielavia ...
EGS20584          304 RFHEFASDEPQQDDWIRRDSITpMPKLTINDTLKKENEIRRLGKEAEEEAEMEEeemdrem----ddeeldeEVDDEALI 379 Chaetomium...
EFX00172          335 RFHEFASDAPLEDDWIRHAKSSmGQRITINDTLKKELAIRLLAKEAEEEAEQEEedeed---------aaenDDDDDDDE 405 Grosmannia...
ERS97169          424 DEEDDD----DNADNDDE--EDE-----DDENDtvegdneylgDERFAGYS---SGASDGYNTDNETGFASSD---DEDD 486 Sporothrix...
EFQ27011          345 DADDVD----EDEDQDDE--DED-----DDEDG-----------------AsdeDDNSDGYKTDEETGFADSEeeeEEDE 396 Colletotri...
XP_003710656      323 EDEDAD----DDEDDEDE----------EDEEDl--------dLDDDESGYgtePE-SEGYRTDEEVGFADSD---DEDD 376 Pyriculari...
Q7RYS7            358 DEDEDSm--dDDEDDNED----------EDEDEd---------LSDSHSVSvwgDDASDGYKTDSEIGFGESDd--EDDD 414 Neurospora...
CAP68477          344 DEDDDEspngDDGDDDDDl-DDE-----ADEEEvee-----eeEDDVNVGYnwdDEASDGYKTDNEIGFAESD---DEDD 409 Podospora ...
jgi:MYCTH_2304224 355 DDDEDDl---QDEDDDEDg-DDE-----DDQGL----------DDVADTEDalaSGASDGYKTDNETGFAASD---DEDD 412 Thermothel...
Q2HA56            362 GSRDED----DDEDDDQDe-DDE-----DDEDEe--------gQDDADTELawaSEASDGYKTDNETGFAESD---DEDD 420 Chaetomium...
jgi:THITE_2119495 363 QEEDAE----DGDEDDVDv-DDE-----EPEEGl---------DDDAETEHawdDEASDGYKTDNETGFAESD---DEDD 420 Thielavia ...
EGS20584          380 DDDDDDf---DEEDDDDDvnDDEiendqNDDVD----------------SDaveEVASDGYKTDNETGFAESD---DEDD 437 Chaetomium...
EFX00172          406 EYDDED----EDEDDDED----------VDENDtvdgdgdrldLSQYSGYNf--DTVSDGYNTDNEVGFASSD---DEDD 466 Grosmannia...
ERS97169          487 GLVLWAVnqpsrq-rrehnFDNDHSTLHqggs-pifRRLSV----DEHSDSSVFVAGRA-MRQDRPKNRELASNIR-RGG 558 Sporothrix...
EFQ27011          397 DLRLWTP------------GRSTVLNIDstp---iaRRPSLp---EQLSDSSIAS-KTS-LRARRGRTQRLK---I-RPG 452 Colletotri...
XP_003710656      377 ELVLWWP------------GTSSGSKTAias---lsRRMSIgqslGNMSDSSAFSPGCT-LQRRMKIPRSSPRATR-RPG 439 Pyriculari...
Q7RYS7            415 DLVLWTT--------------GGLADLSlsgatpvfRRGSV----DESSDSSAGSDGNNvARRALKRRDTIRTRDF-RPA 475 Neurospora...
CAP68477          410 GLLLWTT------------RVGHHQTLSgavl-savRRLSV----GESSDSSAGEGKSS-LVRKKTKRSRSRPVPF-RPA 470 Podospora ...
jgi:MYCTH_2304224 413 DLVLWTT------------RIGHYQSLSgtl--smtRRLSH----SEKSDSSASSGRKS-PQSRKKKRSKTRPVPF-RSE 472 Thermothel...
Q2HA56            421 DLVLWTT------------RIGHYASLSgal--satRRLSQ----GEKSDSSTSSGQKS-SQSRRKKRSKTRPVAF-RSV 480 Chaetomium...
jgi:THITE_2119495 421 DLVLWTT------------RIGRFHTLSgav--amsRRLSL----VEHSDSSTSSHGKT-DRSRKKKHSKARAVPF-RPN 480 Thielavia ...
EGS20584          438 DLVLWTT-------------RIGKYPLSgvv--smsRRLSM----ASVSSGSSSGSRRL-ARGRGKQRRSAKAKSpsRPE 497 Chaetomium...
EFX00172          467 GLVLWTVrqsihtrhsedyRDIGHSTLHqggs-pifRRLSV----GEHSDSSAFVAGQA-IRQDKPKNRELAGS-G-RPA 538 Grosmannia...
ERS97169          559 TPELPDSTDFVCGTFDEDRPLEEAYQSHIAARKRGKTHVIPQDIDPSFPTSDPEDNS-DDEPVNYknraqqlqqahgSAD 637 Sporothrix...
EFQ27011          453 TPELPDSTDFVCGTLDEDRPMEDAYMSCLAARRREKLQLIPQDIDPSFPASDPEDEG-EEEIYNPvh---------hSSD 522 Colletotri...
XP_003710656      440 TPELPDSTDFVCGTLDEDRPLEDEYMSCMAAKRQEKLRLIPQDFDPSFPTSDPEDDD--DEAFKPlh---------rISD 508 Pyriculari...
Q7RYS7            476 TPDLPDSTDFVCGTLDEDRPLEAAYLERMAARKQNKLVFIPQDIDPSFPTSEPEDEG--EELYNKsah------gheDSE 547 Neurospora...
CAP68477          471 TPELPDSTDFVCGTLDEDRPLEDAYISCVEARKRDKVPVIPQDIDPSFPTSDIEDEP--EEPYGKgy---------gESD 539 Podospora ...
jgi:MYCTH_2304224 473 TPELPDSTDFVCGTLDEDKPLEEAYISCVAARRRDRHQPIPQDIDPSFPTSEPEDEV--EELYKKgy---------gESD 541 Thermothel...
Q2HA56            481 TPELPDSTDFVCGTLDEDRPLEEAYISCVEARRRGRQQVIPQDIDPSFPTSEPEDEG--DELHRKgy---------gESE 549 Chaetomium...
jgi:THITE_2119495 481 TPELPDSTDFVCGTLDEDKPLEEAYISCVEARKRVRHQPTPQDIDPSFPTSEPEDEA--EELYRKgy---------gDSE 549 Thielavia ...
EGS20584          498 TPELPDSTDFVCGTLDEDRPLEEAYISCVEARKRSKQKPIPQDIDPSFPASEPEDSD--DGICRRrhv-------ygDSS 568 Chaetomium...
EFX00172          539 TPELPDSTDFVCGTFDEDRPLEEAYMCHMAARKREKYQTIPQDIDPSFPTSDVEGESdDDQTSKYpkqk----qqqgSAD 614 Grosmannia...
ERS97169          638 DRFW---EMEDLHHDQTDKRaDTRqk----kkTVSPRRCRSPPPp--------kTRGRSPapRRlfDRHsPTRRLKSPAP 702 Sporothrix...
EFQ27011          523 DEMFfhgKMDDLHHA-NDRS---Rrrk--kteHTSPKRFHSPPPlkrraspapkARGRSP--RRlfDGPs-PHRLRSPAP 593 Colletotri...
XP_003710656      509 EHVWlhgELEDLDHEGDERH---Drs----rkVTSPRRMHSPPPr---------ARGRSPppRRlfDRHsPPRRMRSPAP 572 Pyriculari...
Q7RYS7            548 DDMW---QLEDLH---SERGrIGRak----kaQNSPRRCRSPPPkrrlspcpkkSRGRND--RNlfDRSs-PRRMRSPPP 614 Neurospora...
CAP68477          540 EHGWlhgEFEDLHHE-RDR----Rgrk--sgkGPSPKRFRSPPPkrrls-papkMRGRSP--LKptERAs-PRRFKSPAP 608 Podospora ...
jgi:MYCTH_2304224 542 DHIWlhgELEDLDHD-RDR----Rgrkk-kggVPSPKRCRSPPPkrrps-papkARGRSP--RKltDQRs-P-RLRSPAP 610 Thermothel...
Q2HA56            550 DHLWlhgELEDLDHE-RDR----Rgrkk-kgsVPSPKRFRSPPPkrrps-papkARGRSP--RKlsDQRp-P-RLRSP-P 617 Chaetomium...
jgi:THITE_2119495 550 DYVWlhgELEDIHHE-RDR----Kgrk--kgaGPSPKRCRSPAPkrrps-papkARARSP--RKllDQRs-P-RRRSPAP 617 Thielavia ...
EGS20584          569 DHLWfhgPMEDLHHD-RDHRkGLRgrkkdtcaAVSPKRCRSPPPkrrgpspapkPRARSP--RKgnDQRs-P-RYRSPAP 643 Chaetomium...
EFX00172          615 DQLWlhgELEDL-HGEPDRSdRCRkm------ekSSRRYRSPPPp--------kARGRSPapRHlfDRQsPSRRMRSPAP 679 Grosmannia...
ERS97169          703 kaipspmpvpinvasshIHAISPP-ASpvdlpadrgRPMFQPLAF-HP--GMTHTKSLP-RPSAIFRHQLataaqaqqhq 777 Sporothrix...
EFQ27011          594 -----------------QTLRSPP-ASprn---gdgGIAFKTLAS-RP--GLTVTKSLP-RPPSMFPHMA---------- 638 Colletotri...
XP_003710656      573 p----------------MASASPQ-ASpig----gqGVVFKSLAF-RP--GLTHTKSLP-RAPAIFTHLKtqhq------ 621 Pyriculari...
Q7RYS7            615 p---------------vLSAKSPL-ASpvt---gadGVAFKSLAF-RP--GLTFTKSLP-KGPVMFPHINkq-------- 663 Neurospora...
CAP68477          609 i---------------sMAYRSSAsSSpgq---dsdHVAFKALAF-RPglGLPHTKSLP-KAPGMFLKQK---------- 658 Podospora ...
jgi:MYCTH_2304224 611 s---------------rGAFKSPI-MSplh---eaeGVEFKSPAF-RP--GLTHTKSLP-RAPGMFPHLK---------- 657 Thermothel...
Q2HA56            618 p---------------lAASKTPV-ISplh---eneAVAFKSLAF-QP--GVTHTKSLPrRASGLFPHLK---------- 665 Chaetomium...
jgi:THITE_2119495 618 q---------------hTTFKSPV-ISpar---egeGIAFKSPAF-GP--GLTHTKSLP-RAPGMFPHLK---------- 664 Thielavia ...
EGS20584          644 p---------------rMASRSPMaVSpadvp-ldgpVVFKPVHFgGPtsVANHTKSLP-PVAVLFPNLQpvagq----- 701 Chaetomium...
EFX00172          680 kltpav------laeppTALVSSR-TSpvei-agvgCVAYQAVAF-RP--GLTQTKSLP-RPAAIFRHQQqnnqaa---- 743 Grosmannia...
ERS97169          778 lqqqqqptakpyrRPKA------NSLAGA-------------------KQPRHVRGAIDIVKGLEQKRQRRREKFQQKYC 832 Sporothrix...
EFQ27011          639 -------------KGRR--------IKAP-------------------ANDVHIRGAIDIVKGLEQKRQRRKEKFYQKYC 678 Colletotri...
XP_003710656      622 ---------haqqRKKS--------TVAH-------------------KDKRHVRGAIDIVKGLEQRRQRRREKLSRQQC 665 Pyriculari...
Q7RYS7            664 ------------qPRRS-------RAGTT-------------------TQDTHVRGAIDIVKGLEEKRQRRKEKYYQKYC 705 Neurospora...
CAP68477          659 -------------ARKA------KVAAEE-------------------KDSTHVRGAIDIVKGLEQKRQRRKEKYYQKYC 700 Podospora ...
jgi:MYCTH_2304224 658 -------------TRKS-------RTGNS-------------------TRETHVRGAIDIVKGLEQKRQRRREKYYQKYC 698 Thermothel...
Q2HA56            666 -------------ARKS-------KSGTA-------------------PKDTHVRGAIDIVKGLEQKRLRRKEKFCQKYY 706 Chaetomium...
jgi:THITE_2119495 665 -------------GRRA-------RAGTT-------------------TRQTHVRGAIDIVMGLEQKRQRRKEKFYQKYC 705 Thielavia ...
EGS20584          702 --------qvpppTRRAtafvprESVSHHmvedieevneeddadnnngSSSTHVRGAIDIVKGLEQKRQRRKEKFFQKYY 773 Chaetomium...
EFX00172          744 --------akparRPKA-------NGTTS-------------------TKPMHIRGALDIVKGLEQKRQRRKEKFQQKYC 789 Grosmannia...
ERS97169          833 NRARKGQVPERRT--Q----RGEGAERMREVGLLMAGKI-RPANYVLSV 874 Sporothrix schenckii ATCC 58251
EFQ27011          679 NRARKGQVPERKP--Q----RGLGCERMRELGLLMAGKI-GQGNYVISV 720 Colletotrichum graminicola M1.001
XP_003710656      666 NRARKGLAQEKRP--A----PGKGAERMRELGLLMAGKI-GPGNYVLSV 707 Pyricularia oryzae 70-15
Q7RYS7            706 TRARKEKAQPKRP--P----PGQGAERMREVGLIMAGKI-GQGNYVLSY 747 Neurospora crassa
CAP68477          701 SRARKEKAKEKAH--PkrtiPGEGAERMRELGLTMAGK--NPGHYVLSi 745 Podospora anserina S mat+
jgi:MYCTH_2304224 699 NRARKEKTQTKRP--P----PGEGASRMRELGLIMAGKA-AHGNYVLSI 740 Thermothelomyces thermophilus ATCC 42464
Q2HA56            707 NRARKEKAQTKRP--P----PGQGASRMRELGLIMAGKI-GQGNYVLSI 748 Chaetomium globosum CBS 148.51
jgi:THITE_2119495 706 --ARKDKAQTKRP--P----PGQGAERMRELGLFMAGKAgGHGHYVLSV 746 Thielavia terrestris NRRL 8126
EGS20584          774 ERARKEAAQGRRAavP----PGTGAERMRELGLLMAGK--REKRYMLSf 816 Chaetomium thermophilum var. thermophilum...
EFX00172          790 NRARKGQALERRP--Q----RGEGAERMRELGLLMAGKI-GQGHYVISV 831 Grosmannia clavigera kw1407
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