Conserved Protein Domain Family
Cytokin_check_N

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pfam10407: Cytokin_check_N 
Cdc14 phosphatase binding protein N-terminus
Cytokinesis in yeasts involves a family of proteins whose essential function is to bind Cdc14-family phosphatase and prevent this from being sequestered and inhibited in the nucleolus. This is the highly conserved N-terminus of a family of proteins which act as cytokinesis checkpoint controls by allowing cells to cope with cytokinesis defects. These proteins are required for rDNA silencing and mini-chromosome maintenance.
Statistics
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PSSM-Id: 402159
View PSSM: pfam10407
Aligned: 37 rows
Threshold Bit Score: 80.2676
Threshold Setting Gi: 74582426
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6FXK6         46 TRKFLHF-TKPENTLLQLADEIENRITKLYSNLniESFEILSLQDINHCDLDATYLVKDVFS-MDNTVLVILKNE 118  [Candida] glabrata
XP_004197352   28 SRKFLHL-TDPETSLEKVCGELTRRFKRLYPFE--EEILIENLQDDDKCDLDAEFKVSDVLG-PGETLRVVIGND 98   Pichia farinosa CB...
CAR65897       28 SRRFLHL-ADSDSDLGKVCDELTKRYAKLYPDD--DKLAIMSLQDDDRCDLDPDFEAGEALN-SGDIIRVIVENE 98   Debaryomyces hanse...
XP_001487312   45 TRKFVHL-AEGSSTLHQVCETLVMRYRKLYPDD--DELQIFLVQDNDMCDLDPDYLVDEVLN-QGDIIRVIASNS 115  Meyerozyma guillie...
EMG47231       29 FVKFLYI-ANKEATIKSLEDGLVSRFSKRYPNE--RKLKILSFQDRDLCDLDPDFAVEDVFDdQNNEIRVLANNK 100  Candida maltosa Xu316
XP_002548257   28 YLKFLYL-VDPNSTIDELEEGLCKRFKRRYPKE--DDLIVFSYQDHELLDLDPEFEISDIFDeQNNEIRILVDNT 99   Candida tropicalis...
Q6CGH4         58 AKRFLYLvSDPDETIEELADKLKATFMELYPHH--AKPCIDSIQDEAALDLDRRFLLREVFE-DNSLVRMVLTQP 129  Yarrowia lipolytica
O74354         16 DNQFMIL-FDPSSSISLLKEKVQETYKSLYPFE--SNINIRNIKNEESYDIPNEYLVGEIFP-TNS--KVIVESf 84   Schizosaccharomyce...
XP_001629050   15 DKKFLVI-ADEDWTVEDVKSCTEVIFSKLYPGE--PSLTVSKLQNEFHFDLPLDYCAGDALV-DSGLVFAIEDEv 85   starlet sea anemone
CCE40181       28 AKKFLHL-IDPVKQIGELLDAVVAQFQRLYPEE--PAINVVKCQDKNQCDLDKDYQVEDVFE-SNDEVRVIVDNl 98   Candida parapsilosis
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