Conserved Protein Domain Family
CRF1

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pfam10380: CRF1 
Transcription factor CRF1
CRF1 is a transcription factor that co-represses ribosomal genes with FHL1 via the TOR signalling pathway and protein kinase A.
Statistics
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PSSM-Id: 371017
View PSSM: pfam10380
Aligned: 13 rows
Threshold Bit Score: 90.6026
Threshold Setting Gi: 1723466
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CCE40089        790 SESTDVDETL---------------------------------------------------------PRnTNLSPQIGs- 811  Candida par...
EMG48022        584 SESTDVDESL---------------------------------------------------------PK-TSKDILKGss 605  Candida mal...
XP_011273115    447 DEATDEDTTL---------------------------------------------------------PPpSSRKK-VG-- 466  Wickerhamom...
Q6C4H0          427 GDSTDEDTTL---------------------------------------------------------PPrTQKKC----- 444  Yarrowia li...
Q10304          279 DDSSDELNTLshqaddegdttdeetpelqnnkllnlstpkksfgqtpriktelsespnsqrtllsavPTpLELSAELAyk 358  Schizosacch...
ybcl:Ecym_4135  610 NESTDEDETL---------------------------------------------------------PPpNSRTRKIG-- 630  Eremotheciu...
Q74ZL9          598 NESTDEDDTL---------------------------------------------------------PPpNSRNRKIG-- 618  Eremotheciu...
XP_003670409    673 DESTDEDDNL---------------------------------------------------------PPpSSRNKNIG-- 693  Naumovozyma...
CCH62351        810 DETTDEDTNL---------------------------------------------------------PPpEARNKSIG-- 830  Tetrapisisp...
Q6FX29          534 DDSTDEDDNL---------------------------------------------------------PPpEARNKTIG-- 554  [Candida] g...
CAR25852        681 DESTDEDDNL---------------------------------------------------------PPpSSRSKNIG-- 701  Zygosacchar...
XP_001644484    698 DESTDEDDNL---------------------------------------------------------PPpTSRSKSMS-- 718  Vanderwalto...
CCE62364        711 DESTDEDDNL---------------------------------------------------------PRpTQKSKSLS-- 731  Tetrapisisp...
CCE40089        812 KKATEVLSSKTAD--------------------------------------YRPPMLGSWvTIDSKPFGIIDGMSTRSLQ 853  Candida par...
EMG48022        606 KKATEVLSSKTAD--------------------------------------YRPPKLGSWvTVDCKPFGVIDGLSTRSLQ 647  Candida mal...
XP_011273115    467 AKAQELLSSSSVT--------------------------------------ARPPALGTW-STDSKPFGIIDGLSTRSLI 507  Wickerhamom...
Q6C4H0          445 NTATEILSSSNIA--------------------------------------SRPPMLGSWvMTKERPFGIIDGLTTRSL- 485  Yarrowia li...
Q10304          359 EDLTSLASRANISdnstgltptlakatlaqpvstvvsvasfeldprlnitqPKPPVMGTWaKEPNHLIGIIDGKHSHSL- 437  Schizosacch...
ybcl:Ecym_4135  631 SKAKEVVSANTVG--------------------------------------LKPPKLGTW-KTDTKPFSIIDGLSTKSLI 671  Eremotheciu...
Q74ZL9          619 TKAKEVVSASTVG--------------------------------------LKPPKLGTW-KTDAKPFSIIDGLSTKSLL 659  Eremotheciu...
XP_003670409    694 SKAKEIVSANVVG--------------------------------------LRPPKLGTW-ETDNKPFSIIDGLSTKSLY 734  Naumovozyma...
CCH62351        831 TKAKEIVSANVVG--------------------------------------LKPPKLGTW-DTENKPFSIIDGLSTKSLY 871  Tetrapisisp...
Q6FX29          555 TKAKEIVSANVVG--------------------------------------LKPPKLGTW-NTENKPFSIIDGLSTKSLH 595  [Candida] g...
CAR25852        702 TKAKEVVSANVVG--------------------------------------LKPPKLGTW-ETDSKPFTIIDGLSTKSLY 742  Zygosacchar...
XP_001644484    719 TKAKEVVGANVVG--------------------------------------LRPPKLGTW-ETNSKPFSIIDGLSTKSLY 759  Vanderwalto...
CCE62364        732 TKAKEIVGSNVIG--------------------------------------LRPPKLGTW-KTNSKPFSIIDGLSTKSLY 772  Tetrapisisp...
CCE40089        854 qqhqqqqhqvpptNKMQEPRGMVVDRRPF--SPASHSGLAMAQSlgkrksyghirqhnmqpsmsmqvqvqgqpnSDDQSV 931  Candida par...
EMG48022        648 -------------NKYQEPRTAPLGNRKSlvAPSRHPQQNQQQQqsqsqqi----------------hhqgsiiSSDDSV 698  Candida mal...
XP_011273115    508 pnsnk---nqsqqSNASGSTNPSLNITTT--GGGGANSLKQSPStp--------------------------lnNNNIEE 556  Wickerhamom...
Q6C4H0          486 -------------SGQKSPPTTNGKSNSN--GGIRYSTAIESDDcs---------------------------dISDLND 523  Yarrowia li...
Q10304          438 -------------HHDKFDACTKGENTAN--NGYGPQTLNETSE-----------------------------------E 467  Schizosacch...
ybcl:Ecym_4135  672 pliqe---hqqllDAQNQQVALGIEGGN-------LASASEFDS------------------------------GAEKEE 711  Eremotheciu...
Q74ZL9          660 plihe----qqllHAHDAPCQQGCGCLP-------AGSASDVDT------------------------------GIEQEE 698  Eremotheciu...
XP_003670409    735 aliqe---hqqlhEQNQ---------REQ--SPD-ISKNNDSNS------------------------------VSNGDE 769  Naumovozyma...
CCH62351        872 pliqe---yqqlmKAEKSESSNENDTNAG--TPNENSQYAASST------------------------------HQDGDE 916  Tetrapisisp...
Q6FX29          596 sliqe---hqqmkEQKLNDITLTKSDFSGtsSPG-------------------------------------------GDE 629  [Candida] g...
CAR25852        743 pliqe---hqhllEQQQ-------RAQSQ--SPE-YHSPHEVTS-------------------------------ANGDE 778  Zygosacchar...
XP_001644484    760 pliqe---hqqlmQE---------RANSQ--SPE-LDSHDDVVT-------------------------------PNGDE 793  Vanderwalto...
CCE62364        773 pliqe---hmqllEG---------RANSM--TPEGVETPNEIPN-------------------------------TNADE 807  Tetrapisisp...
CCE40089        932 LGLDDLLNVSELD------------------------------------------------------------------- 944  Candida par...
EMG48022        699 LGLDELLNISELD------------------------------------------------------------------- 711  Candida mal...
XP_011273115    557 LTLDELLNMSELE------------------------------------------------------------------- 569  Wickerhamom...
Q6C4H0          524 IVLDEFIYTSDLD------------------------------------------------------------------- 536  Yarrowia li...
Q10304          468 PSLDDILDTSLLQpstqtdlqeensvsfaqednslsrwekipigtfrknqyiksmarrdelirdewftlaiktrekrrhk 547  Schizosacch...
ybcl:Ecym_4135  712 LTLNELLNMSELD------------------------------------------------------------------- 724  Eremotheciu...
Q74ZL9          699 LTLKELLNMSELD------------------------------------------------------------------- 711  Eremotheciu...
XP_003670409    770 LTLNELLNMSELD------------------------------------------------------------------- 782  Naumovozyma...
CCH62351        917 LTLNELLNMSELD------------------------------------------------------------------- 929  Tetrapisisp...
Q6FX29          630 LTLNELLNMSELD------------------------------------------------------------------- 642  [Candida] g...
CAR25852        779 LTLNELLNMSELE------------------------------------------------------------------- 791  Zygosacchar...
XP_001644484    794 LTLNELLNMSELD------------------------------------------------------------------- 806  Vanderwalto...
CCE62364        808 LTLNELLNMSDLE------------------------------------------------------------------- 820  Tetrapisisp...
CCE40089        945 ---------------------------------------------ND 946  Candida parapsilosis
EMG48022        712 ---------------------------------------------DD 713  Candida maltosa Xu316
XP_011273115    570 ---------------------------------------------DD 571  Wickerhamomyces ciferrii
Q6C4H0          537 ---------------------------------------------EE 538  Yarrowia lipolytica
Q10304          548 inatgmtttnsvplrpksrkarralkkkarkmtfrqmhsdfqsalED 594  Schizosaccharomyces pombe 972h-
ybcl:Ecym_4135  725 ---------------------------------------------DE 726  Eremothecium cymbalariae DBVPG#7215
Q74ZL9          712 ---------------------------------------------DE 713  Eremothecium gossypii
XP_003670409    783 ---------------------------------------------DD 784  Naumovozyma dairenensis CBS 421
CCH62351        930 ---------------------------------------------DD 931  Tetrapisispora blattae CBS 6284
Q6FX29          643 ---------------------------------------------DD 644  [Candida] glabrata
CAR25852        792 ---------------------------------------------DE 793  Zygosaccharomyces rouxii
XP_001644484    807 ---------------------------------------------DN 808  Vanderwaltozyma polyspora DSM 70294
CCE62364        821 ---------------------------------------------DQ 822  Tetrapisispora phaffii CBS 4417
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