5Y5A


Conserved Protein Domain Family
EST1

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pfam10374: EST1 
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Telomerase activating protein Est1
Est1 is a protein which recruits or activates telomerase at the site of polymerization. Structurally it resembles a TPR-like repeat.
Statistics
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PSSM-Id: 402133
View PSSM: pfam10374
Aligned: 112 rows
Threshold Bit Score: 52.0986
Threshold Setting Gi: 555689144
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5Y5A_A         80 RILDLTWKHVHYPI-FKYFQNWRNRNVAEGsrPNY-AGHRQLN---SILQKIFPQIHKLYYSTLELIFANYNLTALIP-- 152  Kluyveromyces...
ETN63163       64 KSREILWRKGYYDV-ISVLKRQKGNVD-----------GAVLQ---QAADQLIREGSNYFKAIVLRFAELFHLETLKYlv 128  Anopheles dar...
XP_008180969   80 KAEDIMWRKTYHDV-YSTAKILRKNNDwnh-------------melALIENHFQSGIGSYYHLLFKFQAEMKfnkpel-- 143  pea aphid
XP_001599646   77 KTEELLWRRCCYDI-VSAAKKLRKGNAwne-------------teeAFLSVHLSVGAGFYHHLILRLLLEYDlklpgvid 142  jewel wasp
EFN89814       77 KTEELLWRKAFYDV-VYAAKKLRKTNQwne-------------sekALLSVHLAVGVGYYHHLILRLQSEYDldlvgvid 142  Jerdon's jump...
EGI65744       77 KIEELLWRKAFYDV-VYTAKKLRKDNTwnd-------------vekTLLSIHLAVGVGYYHHLIMRLQTEYDldligvvd 142  Panamanian le...
EKC29542       75 KAEEVLWRKVFYDP-IQLVKKNRRHLR----------SGSSLE---AAFRTHLSAATGYYHHLIFRLQSEFSlklhrtvd 140  Pacific oyster
XP_002434319   71 QAEELTWRKVYYEA-VQQFKAPKRGVQGNG--EGErVKDDEEEeavLSLRAHLTSGLGHYHHLLIRLQAEYRldlessvd 147  black-legged ...
ELR51377       68 KAEELLWRKTYSDVvLLLLKPNRKNTD---------SSEEQWE---GPLWAHLKGGLRFYEHLFLFLQEHYQlglwsyid 135  wild yak
XP_030832851   85 KAEEILWWKVYYNV-ITLAKKSKKNIR----------SGSSLE---CAYRTHLLAATGFYHHLLMRLQWEYGlqenh--- 147  purple sea ur...
5Y5A_A        153 ----------SDTRSKlnI-----STKKL-NDDASNVLKPEDSFS-IDCVMASQRCLLYIGCSQRYKIIME 206  Kluyveromyces lactis N...
ETN63163      129 dfallddyddDALRQEascy---sllqLRnEPHATSPQELYTKQEiSYALETIHSLLISLGDLHRYRLEFG 196  Anopheles darlingi
XP_008180969  144 -------------fdfylLvnddtDNNVKkDHITLLKKNDIGNKEeVGMKQLVYRCLICLGDLSRYMYELN 201  pea aphid
XP_001599646  143 faytq------------------nqkeiihmekginKSKVPTLEVkKCVTRFIHRSLICLGDLARYQLDLe 195  jewel wasp
EFN89814      143 faftrfe---------------sissyarwmakmeqPKLTHTKEVkQCVMRLIHRSLVCLGDLTRYKLELD 198  Jerdon's jumping ant
EGI65744      143 fafiq------------------nesissyartktgQTKTHTKELkQCVMRLIHRSLVCLGDLSRYKLELN 195  Panamanian leafcutter ant
EKC29542      141 -----------------fflipesKSGHKkSLSQAVRRRDATPAVqDWATRACHRCMVCLGDIARYQQEFD 194  Pacific oyster
XP_002434319  148 v--------plrwshrglPrgrlsQRRQQpPHHGHDASGQHEESLvLWARQACHRLLLCLGDLARYLSELG 210  black-legged tick
ELR51377      136 wp------------------------hsaihfigckRAGPASEEEvDWARMACHRCLLYLGDLFRFQNEFL 182  wild yak
XP_030832851  148 --------------------vmdfISFPDqDQVKETCMDANKPEAkDWAQKACHRCLIYLGDLARYRQEFE 198  purple sea urchin
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