Conserved Protein Domain Family
Fmp27_GFWDK

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pfam10347: Fmp27_GFWDK 
RNA pol II promoter Fmp27 protein domain
Fmp27_GFWDK is a conserved domain of a family of proteins involved in RNA polymerase II transcription initiation. It contains characteristic GFWDK sequence motifs. Some members are associated with domain Fmp27_SW (pfam10305) towards the N-terminus.
Statistics
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PSSM-Id: 402113
View PSSM: pfam10347
Aligned: 27 rows
Threshold Bit Score: 151.27
Threshold Setting Gi: 121890313
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_011393850 1275 DYPLPFIHVPatkSNQSARLPALTLKTDFVIAEEF-RGVESTRKIRVQVIPPQSHDSSepnKGSFAIDVSRTIGPVKMFS 1353 Neurospora cr...
XP_011388433 1863 DYPMPLLHIPpthRPESDARKAWCFEGDIVLAEQL-GGPESIRHVPVVIVPAATGRLD---AVEYGIIVPKVAMSVKIYG 1938 Ustilago mayd...
Q6LA55       1174 DYPLPLVYIPklgRGQDKRISSWHLKSNMVITEQQ-ATLAAIRDVSVKVIPADLTKEG---I-PYVVNVTRTVSPIKTFS 1248 Schizosacchar...
Q0UCK0       1268 DYPLPLLHFPaigSIQSSRLPSVSMRTDFVIAEEF-RDIESSRVSRVVVVPQDETPLGe-pTGGFAVDVRRTVAPVKTYS 1345 Parastagonosp...
Q0CVI8       1196 DYPLDLLHIPalrPGQSPRLPSWSLRTNFVIAEEY-RDYKSARQVEVELVPPTELPDGt-kSSPFAISVWRSVTPVKTYS 1273 Aspergillus t...
Q6CQQ5        973 DYSLPALFFP-----------NTNVTGDIIFAEAL-GSSKSWRPIFVPFSTLSADHKEl-pDSIFGSDIIRTLTPIKTFM 1039 Kluyveromyces...
XP_001647449 1099 DYPIPIVTFP-----------DTHTTGNVVFAEKM-PGNHSLRSTYVPFVPSTAAEAYtggNSIYGSHVIGTVNAIKTYF 1166 Vanderwaltozy...
Q6FVY3       1091 DYPIPVMSFS-----------QVKTDGDIVFAEKM-PIEDSHRSIFVPFVKSASAVPYnihNSFYGSHIIRTLNSIKIYY 1158 [Candida] gla...
XP_001633968   70 DYPRPIFSST-----------CVKLSGTVVGAEQTaAD-RAKREAIIEID-----------KPWGHMTVQRSLTAFKFYY 126  starlet sea a...
Q7PNQ7       1132 DYPQPMFHVK-----------AMHLFGTLAGAE-MaPPRRAKRDVEIELG-----------EPFGTHTVQRSMTSIKFYH 1188 Anopheles gam...
XP_011393850 1354 DMHIDVHTANPTRITWGPSYQPAVQDMMMAIESLTKPQLDPSERVGFWDKIRLSFHSRFRVTWRGnGDVHLALKGSRDPY 1433 Neurospora cr...
XP_011388433 1939 TPTVKLHTPYPTRLVWGQSIQPTIQDVMRVIDSITPPPHDPSPKLGFWDKLPLILHGHVNMKFEDeGGFNVHLKGSRNPY 2018 Ustilago mayd...
Q6LA55       1249 KTEIDVNSSLPTFLLWCNSYQPALSDMTRIMDTFTKMPIDPSEKLGFWDKIRLVAHSQIRLRWLEdGDVFLSLKGSRDPY 1328 Schizosacchar...
Q0UCK0       1346 DMAIDINSAYPTRITWGTSYQPAIQDMMQIIENFTKPAIDPSERVGFWDKIRLTFHSRINVSWRGdGDVHLILKGSRDPY 1425 Parastagonosp...
Q0CVI8       1274 DPTIEINTSLPTSISWGMSYQPVIQDMMKIIEGFTKPEIDPSERVGFWDKIRLSFHSRIRVIWKEdGDVHLRLKGSRDPY 1353 Aspergillus t...
Q6CQQ5       1040 DIRFTIDSDTPTQITWGKSLQPGYQSVMLWFDFLTKPPMDPSPKVGFWDKIRLLFHGKLEFQWLSnSSMHLNFKGSSDPY 1119 Kluyveromyces...
XP_001647449 1167 DINTNVMSSNSSSITWGKSLQPGYQALMQWFDFLTKPQLDPSPRLGFWDKFRYLAHGSWTYHFSEnSNFLLNVKGSHDPY 1246 Vanderwaltozy...
Q6FVY3       1159 NLNSRTEAATPSFLTWGKSLQPAFESLMLWFDYLTKPPLDPSEKLGFWDKFRFIVHGRWVFKFEKdSSFHLHIKGSYDPY 1238 [Candida] gla...
XP_001633968  127 DLDFDVDT---LEMAWGVDTDPATTMVTLAFDNISKASADPSKPLPWFDKVRLLMHGRLHLVVKE---WLMYFSATRNPY 200  starlet sea a...
Q7PNQ7       1189 DFNWELDY---LAYAFGPCWEPVMAQCNLMMEKISAPSRDPSPPLPFWDKMRLLMHGQLSIIAKQ---FTILLHASLDPY 1262 Anopheles gam...
XP_011393850 1434 EV 1435 Neurospora crassa OR74A
XP_011388433 2019 TI 2020 Ustilago maydis 521
Q6LA55       1329 VI 1330 Schizosaccharomyces pombe 972h-
Q0UCK0       1426 MV 1427 Parastagonospora nodorum SN15
Q0CVI8       1354 VV 1355 Aspergillus terreus NIH2624
Q6CQQ5       1120 SI 1121 Kluyveromyces lactis
XP_001647449 1247 KI 1248 Vanderwaltozyma polyspora DSM 70294
Q6FVY3       1239 KI 1240 [Candida] glabrata
XP_001633968  201 DI 202  starlet sea anemone
Q7PNQ7       1263 NT 1264 Anopheles gambiae str. PEST
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