Conserved Protein Domain Family
MMM1

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pfam10296: MMM1 
Maintenance of mitochondrial morphology protein 1
MMM1 is conserved from plants to humans. MMM1 is an integral ER protein. It is N-glycosylated, and forms a complex with Mdm10, Mdm12and Mdm34 to tether the mitochondria to the endoplasmic reticulum.
Statistics
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PSSM-Id: 402078
View PSSM: pfam10296
Aligned: 49 rows
Threshold Bit Score: 449.328
Threshold Setting Gi: 366986675
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EGC48380  47 LSFTQGLLVGQLSVVLLIGAFIKFFIFGEAPPPPSR--SD-RTSshrr---sysiNT------------ISTDF---SPR 105 Histoplasma capsula...
A5DGW8    81 kSFTQGLIIGQLSVIILLGIFIKFFVFADSSTTSSTsgNGiSsktdvsnilvkrkKN--------------------GDG 140 Meyerozyma guillier...
Q6BH42    69 WSFTQGLVVGQLSVIVVVAIFIKFFVFADSSATTTTtsSsnkdisg---vivkrnKNvrgt----snedKDPNN---NKE 138 Debaryomyces hansen...
CCE73127  71 WNFTHGLVIGQLSVILVIGIFIKFFVFADSQAGPTSassggdsl----givvrsgDKdsn------gteRSNGK---ADS 137 Millerozyma farinos...
A3LSW7    75 WSFTQGLIVGQLSVVFVIVIFIKFFVFAESSPALAKssitkdas----vvivkrdKKdq--------ssSDDAD---PDD 139 Scheffersomyces sti...
Q59SI5    71 WSFTQGLVIGQVSVIFIIIVFVKFFVFADSSSHIPTkpGL-DGAtgviv-krnknKK------------HSNGQ---FAN 133 Candida albicans SC...
EMG47505  65 WTFTQGLILGQISVIFVIIVFVKFFVFADGSTIPTKksalkdas----gvivkrnKQt-----------KKTGA---SSD 126 Candida maltosa Xu316
A5E3T2    77 WNFTQGLVVGQLSVIFLIIIFVKFFVFADSSSSIPSkfvardga----gvivrrdNKsttsrdrhngigGKDSNlepSTD 152 Lodderomyces elongi...
CCE44449  77 WSFTQGLIVGQLSVIFIVVIFIKFFVFADSSTTPSKtiirdas-----gvivkrdKKqannkrnsylnpEEADA---SAE 148 Candida parapsilosis
C4Y0Q6    30 WSFTQGLMCGQASVVVVLLVFIKFFVFSEAPPSSGAakSkkkdisg---vivkreAK---------------NT---DDD 88  Clavispora lusitani...
EGC48380 106 TLREKPStsnilrpvpsssTNTRSILRKTYYSatptnptskhgrsrvhHSSHQPESLDWFNVLIAQTIAQYRQTAYilkd 185 Histoplasma capsula...
A5DGW8   141 DAGSEGRs-----------DEVDTILEKTYYD----------------VDNHAPESLDWFNVLIAQTISSFRYEAL---- 189 Meyerozyma guillier...
Q6BH42   139 DDLNSPNl-----------SKISTILEKTYYD----------------VENHSPESLDWFNVLIAQTISQLRTEAL---- 187 Debaryomyces hansen...
CCE73127 138 EPKMIGN------------AKISTILEKTYYD----------------VDNHAPESLDWFNVLIAQMISQLREEAL---- 185 Millerozyma farinos...
A3LSW7   140 DSETTASn-----------AKVAAILEKTYYD----------------VDNHSPESLDWFNVLVAQTIAQLRSEAL---- 188 Scheffersomyces sti...
Q59SI5   134 DGENEDDtsld-----snqSKISSILEKTYYD----------------VNNHASESLDWFNVLVAQTISQLRSEAL---- 188 Candida albicans SC...
EMG47505 127 DIIEDEKlvd-------irSKISTILEKTYYD----------------VNSHSPESLDWFNVLVAQTISQLRTEAL---- 179 Candida maltosa Xu316
A5E3T2   153 DERLQNNr-----------AKVSSILEKTYYD----------------VNNHASESLDWFNVLIAQTISHLRTEAL---- 201 Lodderomyces elongi...
CCE44449 149 DERLLSNr-----------AKVSAILEKTYYD----------------VHNHAPESLDWFNVLIAQTISHFRTEAL---- 197 Candida parapsilosis
C4Y0Q6    89 DGVENGDs-----------AKLATILEKTYYD----------------VNNHNPESLDWFNVLIAQTISQLRCEAL---- 137 Clavispora lusitani...
EGC48380 186 sPTSSILASLSEALNnPEKKPSFIDTIKVTDISLGEEFPIFSNCRViavedPNsDGGRLQALMDVDLSdDNLSLAVETSL 265 Histoplasma capsula...
A5DGW8   190 -QSDNIYHSLKEFLS-KSELPDYLGDIQLTEIDIGDDFPIFSNCRIrp--sKD-SHGRLEAKIDVDLS-DTLTMGIQTKL 263 Meyerozyma guillier...
Q6BH42   188 -LSDNIYHSLNEFLT-NSDLPDYMDKIKLTEIDIGDDFPIFSNCRIkh--sKD-RSGRLEAKIDVDLS-DTLTLGIETRL 261 Debaryomyces hansen...
CCE73127 186 -LSENIYHSLNEFLT-NSELPDYLDTIRITEIDIGDDFPIFSNCRIkh--sKD-GSGRLEAKIDVDLA-DTLTFGIETKL 259 Millerozyma farinos...
A3LSW7   189 -LSDNIYHSLNNFLL-KSELPEYLDKINLTEIDIGDDFPIFSNCRIkh--sKD-GSGRLEAKIDVDLS-DTLTLGIETKL 262 Scheffersomyces sti...
Q59SI5   189 -LKDNIYHSLNNFLT-NAKLPDFIDTINLTEIDIGDDFPIFSNCRIky--gED--LKRLEAKIDVDLS-DTLTLGIATKL 261 Candida albicans SC...
EMG47505 180 -LSDNIYHSLNNFLE-TTNIPEFMDKINLTEIDIGDDFPIFSNCRIky--gED--LGRLEAKIDVDLS-DTLTLGIATKL 252 Candida maltosa Xu316
A5E3T2   202 -LSDNIYHSLSNFLD-NSELPDFLDKINLTEIDVGDDFPIFSNCRIkh--sKE-DTGRLEAKIDVDLS-DTLTLGMETKL 275 Lodderomyces elongi...
CCE44449 198 -LADNIYHSLKDFLD-QSALPDFMDKISLTEIDIGDDFPIFSNCRIkq--sNE-DTGRLEAKIDVDLS-DTLTLGIETRL 271 Candida parapsilosis
C4Y0Q6   138 -LSDNIYHSLNDFLE-TSDLPDFMDKITLTEIDIGDDFPIFSNCRIqh--sAD-GTGRLEAKIDVDLS-DTLTLGIETRL 211 Clavispora lusitani...
EGC48380 266 LLNYPKPFSAVLPVALAVSVVRFSGTLCISFvpgPGTSDQTmgpsasppnqttstetasin-dqtsegqstqrhtfhqhk 344 Histoplasma capsula...
A5DGW8   264 ILNQPRPLTAVLPISLSVSIVRFSGCLTVSLi-nTNEEEFSepr------------------------------------ 306 Meyerozyma guillier...
Q6BH42   262 LLNHPRPLTAVLPVQLSVSIVRFSGCLTVALi-nTNDEEFLdlqnvttpspgpsnepnsqnqtqqptpvnnsssrashdv 340 Debaryomyces hansen...
CCE73127 260 VLNHPKPFTAVLPIHLSVSIVRFSGCLTVSLv-nTSDQEFVgmqhassrntgasesqagr---nepaavnndphsrshth 335 Millerozyma farinos...
A3LSW7   263 LLNHPRPLTAVLPVQLSVSMVRFSGCLTVSLi-nTADPEFAelsahnspepgepmsrshs---agspggdsshdevistp 338 Scheffersomyces sti...
Q59SI5   262 LLNQPRPLTAVLPVSLTVSIVRFSGCLTVSLi-nTKDIDLKnvdktsnmn------------------------gysken 316 Candida albicans SC...
EMG47505 253 LLNQPRPLTAVLPVSLAVSIVRFSGCLTVSLi-nTKDIDLKni------------------------------------- 294 Candida maltosa Xu316
A5E3T2   276 LLNYPRPLTAILPVAMTVSIVRFSGCLTVSLv-nTNDQEFQadqvarps-------------------------nghtst 329 Lodderomyces elongi...
CCE44449 272 LLNHPRPLTAVLPVALTVSLVRFSGCLTVSLi-nTNDQEFVdskyinnnnt---------------------ssnnkpes 329 Candida parapsilosis
C4Y0Q6   212 LLNHPRPLTAVLPVQLTVSMVRFSGCLTVSLv-nTNDTDFV--------------------------------------- 251 Clavispora lusitani...
EGC48380 345 ptNSTPTAATADDAHTKhahgiPKTSLAFSFLPDYRLDLSVRSLIGSRSRLQDVPKVAQLVEARMQAWFEERVVEPRVQV 424 Histoplasma capsula...
A5DGW8   307 vaMDSPQSTRDDNSEEP-----NGTALLFSFSPDYRLEFNVKSLIGSRAKLQDVPKISSLIEHRLRSWFVERCIEPRFQV 381 Meyerozyma guillier...
Q6BH42   341 psSSETKHSKAKRSQED-----TGTALMFSFSPDYRLEFTVKSLIGSRAKLQDVPKISSLIESKLRSWFIERCIEPRFQV 415 Debaryomyces hansen...
CCE73127 336 ngSRDSAESSSGKSNDE-----TGTALMFSFSPDYRLEFTVKSLIGSRAKLQDIPKISSLLESKLRAWFTERCVEPRFQV 410 Millerozyma farinos...
A3LSW7   339 dsSSHTAQRKHSKDDPN-----DGTALMFSFSPDYRLEFTVKSLIGARAKLQDVPKISSLIENRLRAWFIERCIEPRFQV 413 Scheffersomyces sti...
Q59SI5   317 anGDGASSSNNDEDEDD-----GGTALMFSFSPDYRLEFIVKSLIGSRAKLQDVPKISSLIENQLRTWFIERCVEPRFQV 391 Candida albicans SC...
EMG47505 295 dkTKEEEELSEEDNEDE-----GGTALMFSFSPDYRLEFVIKSLIGSRAKLQDVPKISSLIESKLRTWFHERCVEPRFQV 369 Candida maltosa Xu316
A5E3T2   330 dnGNDENGKGSSSEDKK-----GGTALMFSFAPDYRLEFVVKSLIGSRAKLQDVPKISSLIENRLRTWFIERCVEPRFQV 404 Lodderomyces elongi...
CCE44449 330 ngSQQHQRNNDSDNDNG-----NGTALMFSFSPDYRLEFVVKSLIGSRAKLQDVPKISTLVENRLRTWFIERCVEPRFQV 404 Candida parapsilosis
C4Y0Q6   252 -------GTSKEENSSG-----GGTALMFSFSPDYRLEFSVKSLIGSRTKLQDVPKISDLVDSKLRNWFSDRCVEPKFQV 319 Clavispora lusitani...
EGC48380 425 VGLPNIWPRMGRT 437 Histoplasma capsulatum H88
A5DGW8   382 VKLPSLWPRKKNT 394 Meyerozyma guilliermondii ATCC 6260
Q6BH42   416 VKVPSLWPRRQNT 428 Debaryomyces hansenii CBS767
CCE73127 411 VKLPSLWPRRKNT 423 Millerozyma farinosa CBS 7064
A3LSW7   414 VRLPSLWPRRKNT 426 Scheffersomyces stipitis CBS 6054
Q59SI5   392 VRLPSLWPRTKNT 404 Candida albicans SC5314
EMG47505 370 VRLPSLWPRTKNT 382 Candida maltosa Xu316
A5E3T2   405 VKLPSLWPRTKNT 417 Lodderomyces elongisporus NRRL YB-4239
CCE44449 405 VRLPSMWPRTKNT 417 Candida parapsilosis
C4Y0Q6   320 VRLPSMWPRSKNT 332 Clavispora lusitaniae ATCC 42720
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