Conserved Protein Domain Family
DUF2465

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pfam10239: DUF2465 
Protein of unknown function (DUF2465)
FAM98A and B proteins are found from worms to humans but their function is unknown. This entry is of a family of proteins that is rich in glycines.
Statistics
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PSSM-Id: 402031
View PSSM: pfam10239
Aligned: 37 rows
Threshold Bit Score: 318.812
Threshold Setting Gi: 167880864
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WGS:AAQB:GK12865-PA   8 LDSLQALRYEGACLEQ-KNFCKAVDEGIDS--GDLRDVIFWLANELHVLRKT-DERVTs--SGKDHDEFAFELSLLLTEL 81  Drosophi...
Q16TF4                4 SNILLQLGYTLPQDDEaVSLEGIQSAGLSN--RNYRDLVCWLTQIIKQYAPEvDETVS---SVDDLHSFAMEISSFLKEL 78  yellow f...
WGS:AANI:GJ24672-PA   8 IDSLDALGYKK--VEQ-ETLCQALDSGIGS--GDLREVIYWLADQLHVLRKT-DEHVAs--SSKDHNEFAFELSLLLTEL 79  Drosophi...
Q9VBK9                9 VDSLKALSFQGHCQKQ-ENLSRALDAGIES--PDMQEVVLWLAHELHILRKT-DERVNq--GKALNKDFSFELSLLLTEL 82  fruit fly
XP_001954356          8 VDSLQALAYEGPCLQQ-ENLSRALDAGIES--PALRLVIHWLAQELHVLRKT-DERVSs--GSGDHDEFSFELSLLLTEL 81  Drosophi...
Q16TF5                6 LDELRNVGYDGPFLDH-NYASSALAAGAKS--GEFQDMVIWLTDEIRVLGKL-DEKIT---KSDDANTFVLELSGFLKEL 78  yellow f...
XP_003242790          6 LEDLRSLGKS---ISV-KEFRKSINGGPKS--IKYTQLVEWITKEIQILLGL-EEHVNsisSEADSSSFLLEVSSFLKES 78  pea aphid
EEC02016              6 LTALEDLRYDGPFANE-DVFTKEIEDSKS---IKFTELVSWLSVELNKLANM-EDRVNpitDVEDWNTFLLEMSAFLKET 80  black-le...
EFX83447              7 CTSLQNLGYTGPINDV-VQMARLLERNDPGyiVDLSKVVNFLSLKLGSLCQL-EDLVNaieKPEEGEMFCMELAGLLREL 84  common w...
XP_015790216          9 IESLELLKY--PQVE--SLLTKGTPNNLSL--LEFSAIVHWLTDELNDMLHH-DYIVNelsSEAELDAFKIELNSLLRGL 81  two-spot...
WGS:AAQB:GK12865-PA  82 QCPYRQLVIGPIAERFQKRDSLLQLLEYLTTELMATKMSLKTqrsiEPPTKKSKT-----ESNIQQKILELSRDLNLGvD 156 Drosophi...
Q16TF4               79 SCPYHRLLDGPLSSRYRSEEDSLLLIEFLAAECVTGVINQQK----RNEEMKHQIdlvqhPGTPLSTVMQMFQLLDLDvN 154 yellow f...
WGS:AANI:GJ24672-PA  80 GCPYRQFVAVPMSERFQTRTSLLHLLDYLTSELMATKMSLKLqp-aEPPSKKSKT-----ESHLQETVTQLTADLQLG-E 152 Drosophi...
Q9VBK9               83 GCPYRELVQGPIEQRFKSRMALVQLLEYLTSELMTTKMVLKAqp-vGPPCKRSKV-----DTNVQQVVENLAKDLQLG-E 155 fruit fly
XP_001954356         82 GCPYRKLVIGPIEERFQTRESLVQLLEYLTSELMATKMVLKAqp-vGPPCKRSKT-----ESNAQQAIEQLAKDLQLG-E 154 Drosophi...
Q16TF5               79 TCPYANLTSGHVSDRLQTYDSKIILLEYLINELMAFKMIESLk-----PKKEKVNvitlfESPTASALKDISITLGLG-K 152 yellow f...
XP_003242790         79 GCSYNTLIDGHFENRLNSDENKLLLLDYLIGELRASRIINASt-----TNTKCNMqvtliESNTSKYVKEILMTLKFP-K 152 pea aphid
EEC02016             81 HCPIKALTDGSVNQRLMSKENRLMLLGFLCDELQAARMIKVLkpesNALQVe--------MSPTAKAMKGMLMTLGFG-K 151 black-le...
EFX83447             85 YCPYSVLMDGPPVARLTNRENRFKLLNFLISECQAAMMNNLEnqleKCSLKt--------ETPTAEKLKSALMTLGFS-K 155 common w...
XP_015790216         82 QSPL-------TGCDLKVDTNRLAILNCLCGELMASRILFVN------KPADGSMkidmnESETAKDLKTSMIILGIG-K 147 two-spot...
WGS:AAQB:GK12865-PA 157 LP-KNLNTKMLFDKFTPRLEQLLkqtnPKVVSES--LLdpNKPLSDSLWRLLETMHKDLDGEYNLRRQMMLTRLEATVQS 233 Drosophi...
Q16TF4              155 SMgTDITDSETFNRIIHRLKEFF----ATDFNAPdlLFvpKTNLNEAQWAQLDQCHTDLQEEYNLRRQMMMTRLDVTMLG 230 yellow f...
WGS:AANI:GJ24672-PA 153 LP-KNINTKQLFERLTPKLEQRLkqtsPAVISEP--LMrtNKPLTDAQWRVLESMHRDLDAEYNLRRQMMLTRLEATVQS 229 Drosophi...
Q9VBK9              156 VP-KNINTKMLFEKITPRLEQAIkktnPQVLSEP--LLklKKPLTDAQWQLLETLHRELEAEYNLRRQMMSTRLEATVQS 232 fruit fly
XP_001954356        155 LP-KNINTKLLFEKLIPTLDQSLkktnRQVVSEP--LLnlKKPLNDAQWRVLESLHRDLEAEYNLRRQMMTTRLEATVQS 231 Drosophi...
Q16TF5              153 PP-NNIPVKVLFEKINVHLDDTIriagEKRLSTP--LFtpKKKLTMEQWNKLDSLQKDLDGEYDLRRKMLLTRLDVTIQS 229 yellow f...
XP_003242790        153 PP-QNINTSSLFNKVNTKLQDLLktvpPALIGKS--LV--CNSYTSEQWKYINTSIELLNEEFNIRSKMLLTRLDVTVQS 227 pea aphid
EEC02016            152 PP-PNITPAQLFSKTETKVRELLpkagPDTLGKP--LF--QGGLTEKQWFALAKLQAQMQEEYRIRRETLIKRLDVTVQS 226 black-le...
EFX83447            156 PP-SDISAKQLFNKMGVKIREILstapKDYPGSP--LL--KTSLAEQQWSQLHQLLGELNKDYKLRREMLLTRLDVTVLS 230 common w...
XP_015790216        148 PP-ANVQSSQLFSKMKEKINEKLkkstLASEEPL--LLkdGTQFVPKEWNVLNRINTALFEDYNIRRQTLITRCDCTIGS 224 two-spot...
WGS:AAQB:GK12865-PA 234 FQWSESMHnr---eNEIVSRFQNKLKELEQlrygGDDTNIVALLAARK------------------DLAIIEKTSSAQVR 292 Drosophi...
Q16TF4              231 FQWKGDTK------LDVAQIWRQKRRNLDAlttnLNRRDISDLLVAER------------------SLLTMEKVASTRIK 286 yellow f...
WGS:AANI:GJ24672-PA 230 FQWSESMKkr---qGEIGDRFQRKLKEIEKlqygGDDTNIVALLAARA------------------DLAIIEKTSSANVR 288 Drosophi...
Q9VBK9              233 FQWSESMRqr---sNEIMDRFNRKMRELDQfkvgGKQTDLVALLAARS------------------DLAIIEKTSSANVR 291 fruit fly
XP_001954356        232 FQWSESMHqr---eNEIMDRFQRKLRELEQfkvgGEQTNLVALLAART------------------DLAIIEKTSSANVR 290 Drosophi...
Q16TF5              230 FKWSTRVKgk---dGQMNERYAEKRKVLDSlqtgGKDTDLAALLGARE------------------IMAIIEKTSSASVR 288 yellow f...
XP_003242790        228 FKWPDRLKnk---kQKLEEIYQTKLNLINK----LPNFCTSDFLLARD------------------DLAIVEKTSSMLAV 282 pea aphid
EEC02016            227 FKWGDRLKgk---eDKIVQVYQPRRQLMQA----EPRVSLGHVLAARE------------------DLLAIEKTSGAGVR 281 black-le...
EFX83447            231 FTWSPNVKsk---mDEVSAIFQPLRSSMLA----EPNVNISRLLSARE------------------DVAYEEKTSSASVR 285 common w...
XP_015790216        225 FKWKEGEKkdtclsEKIETAYGKLRTILDP----KPNVSLAHALAARKsgcfellnsvvskshqicDIETPKTKGMANVG 300 two-spot...
WGS:AAQB:GK12865-PA 293 KNTTSKIQKHVIgrVPDRGGRANEHAPPppEMPSWQQqRASG 334 Drosophila willistoni
Q16TF4              287 GSKKNVFQGNLT--LPNRGGVVSINAKP--HMPVWSS-REEG 323 yellow fever mosquito
WGS:AANI:GJ24672-PA 289 KNTASKIEKHVIgnVPDRGGRANEHAPPppEMPSWQQqRAGG 330 Drosophila virilis
Q9VBK9              292 KNTASKIQKHVIgrVPDRGGRANEHAPPppEMPSWQQqRASG 333 fruit fly
XP_001954356        291 KNTASKIQKHVIgsVPDRGGRANEHAPPppEMPSWQQqRASG 332 Drosophila ananassae
Q16TF5              289 KNTKSKIQRHIIgrVPDRGGRAYEHKPPplEMPSWQTqRSTG 330 yellow fever mosquito
XP_003242790        283 QNTNSSVNKVMIgqVPDRGGRPNEQQAPppEMPSWQQ-RTQs 323 pea aphid
EEC02016            282 QNTKSAVNRVLIgsVPDRGGRPEDQQPPppEMPSWQK-RTEG 322 black-legged tick
EFX83447            286 EKTKTPLQRMLIgeVPDRGGRATENRRPppEMPGWQK-RKPd 326 common water flea
XP_015790216        301 KQQRISLQKFLIghVPDRGGRPQEQ--PpvPQETFQQqQNQr 340 two-spotted spider mite
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