6UCA


Conserved Protein Domain Family
N6-adenineMlase

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pfam10237: N6-adenineMlase 
Probable N6-adenine methyltransferase
This is a protein of approximately 200 residues which is conserved from plants to humans. It contains a highly conserved QFW motif close to the N-terminus and a DPPF motif in the centre. The DPPF motif is characteristic of N-6 adenine-specific DNA methylases, and this family is found in eukaryotes.
Statistics
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PSSM-Id: 402029
View PSSM: pfam10237
Aligned: 135 rows
Threshold Bit Score: 51.3845
Threshold Setting Gi: 0
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6UCA_A              147 TNAQYLFADRS----CQFLVDLL--Sa-----lGFRRVLCVGTPRLHELIKLtasgDKK---------SNIKSLLLDIDF 206
XP_003117362        205 GESQFFFSDETlgviVKAVEKS-----------KVDGILCIGAPRIFETIRA----LHP----------EKNVFLLDYDK 259 Caenorha...
7_pfamImport          4 GESQFFFSDESlnviLKAVEKS-----------KSDGVLCIGAPRIFEn---------------------VRALFPEKNS 51 
XP_009020128        162 SNAQYMFSKETkdflIHSIIDQ-----------KFNHVLCIGAPSIHEELLV----MGKqmsgekddgCVINSYLLDLDE 226 Helobdel...
XP_001949879        149 SESQYFFTENTiemlVKMFRSV-----------GTTNVICIGAPTIHERIFC----DVP----------EMKSFLLDIDH 203 pea aphid
WGS:AAPU:GI18794-PA 101 VHAQYFFDQQAlkffADQCRLL-----------KIDKVVCMGAPRLHFYLRI----HK------------IQSFLLDFDE 153 Drosophi...
FlyBase:CG12863-PA  108 VNAQYFFDEAAlnflANQCEHI-----------GASKVICMGAPRLHFHLRH----K-------------LQSFLLDLDE 159 fruit fly
EEC02515            151 TKAQYFFSDACvaflCSLLEQQ-----------HFESVICVGAPTIHEHLRE----SCP----------QLPSILLDIEQ 205 black-le...
XP_015792219        140 KEAQYFFDNITvnfiIQTFQKL-----------ELNRIICIGCPSIHEQVQS----NKRs--------WNMESVLLDIDP 196 two-spot...
4_pfamImport          4 ENQQYFYSRKT----AQLLIDAIfdFfeydedrISKELCCLCVPSIAEILYH----DHg-----------ISVALLDFDR 64 
6UCA_A              207 R-------YsQFYMEDsFCHYNMFNHH--F-FDgktalevcrAFLqe-----dKGEGIIMVTDPPFggLVEPLAITFKKL 271
XP_003117362        260 R-------FaKFFPSKqYAQYSMLVDHffD-KNaep---klmEFFq-------NSKSILLITDPPFgvFMEPLLKTIEKM 321 Caenorha...
7_pfamImport         52 KkklhalsFpYFFGCVsTRHYNSENTVfqH----------------------------------------------LQV- 84 
XP_009020128        227 R-------IiKMSPS--SSHYNMFNHYffT-PSsks---eylKFLksardldeSGSNVIILIDPPFggFIELILFTLATV 293 Helobdel...
XP_001949879        204 R-------YlQFYESDhFRWFNMYNCHilEeCDtdl---vleDILt-------QGDSTAVFIDPPFggRLEPLAYTLEKF 266 pea aphid
WGS:AAPU:GI18794-PA 154 R-------FsKYLSPQeFCLYNMCNNHffYqre------pfeRFLkc-----nKDERVLIVTDPPFgcRTELIAHTLRSL 215 Drosophi...
FlyBase:CG12863-PA  160 R-------FaEYLGPEeFCLYNMCNNHffYdrt------pfeQFLag-----tSSDRLVIVTDPPFgcRTELISHTLRSL 221 fruit fly
EEC02515            206 T-------YeQFYGPSeFGWFNMFNGFffRgSSaek---tvqRHLs-------LGTRCALLIDPPFggLVDAIARTLAKM 268 black-le...
XP_015792219        197 R-------YcQFYLRKhFIMFNMFNGFffEgNEgqs---kldRFLre-----cEPGRACVVIDPPFggLLKALGRSLDQI 261 two-spot...
4_pfamImport         65 R-------FdYL---PgYRHFDLLNPT--V--P---------SAK--------SPPFSMVLFDPPYfgIAYEALRASLAT 113
6UCA_A              272 IAMWkegqsqddshkelpifwifpy-----------ffesricqffpsfqmldyqvDYDNHAL 323
XP_003117362        322 KKRFestgkditsfysmivlpi----------------yirkyvlhdnfwmsdyrvTYVGHKL 368 Caenorhabditis remanei
7_pfamImport         85 --------------------------------------------------------TYEGHKL 91 
XP_009020128        294 AKEFygkdskrelctilfhpyf----------------meekicsktsfnmsdytvTYENHKK 340 Helobdella robusta
XP_001949879        267 DQIRkknnksilskflvlpyfm----------------erfvvnclpgmsmldykvDYINHKK 313 pea aphid
WGS:AAPU:GI18794-PA 216 MRLHnrlnqlpatplsifwvypyy-------------manyirqdmpelqmcdyklNYTNHSR 265 Drosophila mojavensis
FlyBase:CG12863-PA  222 RKLHnqinrlpstplsifwiypyy-------------sanhirqempelemceyriNYTNHLR 271 fruit fly
EEC02515            269 VSDAaavgsalsifwffpyfne-----------------kriveampslrmldfavDYRNHVT 314 black-legged tick
XP_015792219        262 HDRYlelhghpgttgstavklnrdsyqfavmlflpyfnepkvaqymknlkltdykvHYTNHRA 324 two-spotted spider mite
4_pfamImport        114 VAGPrtrvlmnfvrrdehillkefpq--------lsrtnsvveydrvsdskwsnygLYANCDL 168
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