Conserved Protein Domain Family
KLRAQ

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pfam10205: KLRAQ 
Predicted coiled-coil domain-containing protein
This is the N-terminal 100 amino acid domain of a family of proteins conserved from nematodes to humans. It carries a characteristic KLRAQ sequence-motif. The function is not known.
Statistics
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PSSM-Id: 402004
View PSSM: pfam10205
Aligned: 13 rows
Threshold Bit Score: 107.957
Threshold Setting Gi: 74947741
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9VC66        18 QKLATEYSKLRAQATVLKKAVLEEQSKEASLREQLQQYATSLRRTEQEVDSLGFRNKQLESRVSQLQQEISVHEqpkkkd 97  fruit fly
ELK14716     121 QKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEpr---g 197 black flying fox
XP_003964249  12 SKLAQEYSKLRAQNQVLKKAVVDEQANCVSLKDQLKQRDQSLRKQEQEMDSLSFRNQQLAKRVELLQEELAVCEa----- 86  torafugu
Q5U3A8         9 SKLAQEYSKLRAQNQVLKKAVVDEQSSCNSLKDELKQKEQSLRRVEQEMDSLSFRNQQLMKRVELLQEELLLSEsk---s 85  zebrafish
O61853        17 QRLAQEYTKLRAQAKVLREGVIEERGKVDKLTEELKSKEAVIRRIQAENESLTFRNDQLVRRVENFQFEPPTTPa----- 91  Caenorhabditis ...
Q173A0        10 QKLAAEYSKLRAQATVLRRAVLEEQSKNAALRESLKEKESNLRKTVQEVDSLGFRNKQLERTVASLQQDLE-EL------ 82  yellow fever mo...
Q7QB23         3 QKLATEYSKLRAQASVLKRAVLDEQNKNSSLRESLRLKEATLRKSEQEVDSLGFRNKQLERRVAALQENLEHEL------ 76  Anopheles gambi...
ETN65196      10 QKLATEYSKLRAQASVLKRAVLEEQNKNASLRESLRTREATLRKSEQEVDSLGFRNKQLERRVAALQENLEQEL------ 83  Anopheles darlingi
EEN53247      11 QRLAQEYAKMKSQHSVLKKAVIDEQSKVAELTESVKLKDLSIRKFEQEIDSLTFRNQQLAKRVTVLQDELDSAAv----k 86  Florida lancelet
XP_011682694   9 QKLAQEFAKVRAQNQVLKKAVIEEQAKQNDAKEQLKVRDQKIRKFEQELDSLTFRNQQLTKRVNFLQDELDIHEsk--gg 86  purple sea urchin
XP_974102     12 QKLATEYSKVRSQATVLKKAVLEEQAKNNELKDTIKKHEQKIRKHDQEMESLTFRNEQLTKRISVLQQELQVNSh----v 87  red flour beetle
XP_003293191  33 QKVVNNYQKIKTQNAILKKALVQEQQKTNDLEKTVKEKEQALVTALQEHDVLDFNNQRLTKRITLMQEEFMNSG------ 106 Dictyostelium p...
Q54N90        37 QKIVNNYQKVKNQNAILKKALLQEQQKTNDLEKGLKEKEQALTTSLQEHDVLDFNNQRLTKRIQLMQDHMNE-------- 108 Dictyostelium d...
Q9VC66        98 KDsggrrgvqSNSR------------------PD 113 fruit fly
ELK14716     198 KK--------NKKSgdsssqls--qeqksvfdED 221 black flying fox
XP_003964249  87 KGk------kGKNKgdspsqha--letknvfdED 112 torafugu
Q5U3A8        86 KK--------SRSKgdspsqvs--lqaqsvfdED 109 zebrafish
O61853        92 ---------aSKSHsskksttptqsdsaaaaaAR 116 Caenorhabditis elegans
Q173A0        83 KKantk-ghkSKNVsinesivp---vdtqvirED 112 yellow fever mosquito
Q7QB23        77 KKvsggktlkTKSSnndlnavag-tettgviaEE 109 Anopheles gambiae str. PEST
ETN65196      84 KKgsggkaakTKSPsnesitgs--gsdggviaEe 115 Anopheles darlingi
EEN53247      87 KK--------NKAKgpvepvpv--vadtsvfgED 110 Florida lancelet
XP_011682694  87 KK--------SKNKdmdnathv--ktspnvigEE 110 purple sea urchin
XP_974102     88 KK--------GKNKsteniiq----sdtsvldEE 109 red flour beetle
XP_003293191 107 KKesgg-qwfGRNTkielqkke---deinvlrSE 136 Dictyostelium purpureum
Q54N90       109 KKesggqwfgGKNQkleiqkkeeeinilrselqe 142 Dictyostelium discoideum AX4
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