Conserved Protein Domain Family
Laps

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pfam10169: Laps 
Learning-associated protein
This is a family of 121-amino acid secretory proteins. Laps functions in the regulation of neuronal cell adhesion and/or movement and synapse attachment. Laps binds to the ApC/EBP (Aplysia CCAAT/enhancer binding protein) promoter and activates the transcription of ApC/EBP mRNA.
Statistics
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PSSM-Id: 401977
View PSSM: pfam10169
Aligned: 33 rows
Threshold Bit Score: 69.3241
Threshold Setting Gi: 121957791
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q7PNZ0         1 MTARCKKRRnQNNAIRRAKNKVKEVKKLKKMLGFieeDVGEGNLMDKLKDITEQKK--KEEELELLKKETLAeivqKEqk 78  Anopheles gambi...
XP_009014417   3 KSMRSKRKR-KMRAIKRNKLDVKLTEKMKIKSNM-----IKDQEVASLVNLTTTLDenNGQCKDNNEt------------ 64  Helobdella robusta
XP_011267025   3 KSLRSKWRR-KCRAVKRERYAVKELDRLKKTLGIe--NAPKDVEMADIQEIATVVD--AKKIKEEQA--KAKdtksDA-- 73  Florida carpent...
XP_011051019   3 KSLRSKWKR-KCRAIKRERYAVKELDRLKKTLGId-dNVSKDIEMTEITEIATVVD--AKKVKEDVKAKRVEdvksKT-- 76  Panamanian leaf...
XP_012063967   3 KSLRSKWKR-KCRAIKRERYAVKELDRLKKTLGIdddNVSKDIEMTEITEIATVVD--AKKIKEDVKAKQVKdaksTT-- 77  Atta cephalotes
Q9VZC8         3 RNNRSRKRRdEMNKIKKARYEAKELIRLKKTLGLldaDGNE--IMKDISDVVEIKT--AKELKREAKSKEEQeliyEHqe 78  fruit fly
EDV95624       3 RSNRSRKRRdEMNKIKKDRYDAKELIRLKKTLGLldaDGKE--IKMEIGEVAEIKS--AKDIKKAAKTREHQeliyEHqe 78  Drosophila grim...
EDS41626       1 MTARSKSRRdKNNRIRRAKNKVKELKKLKKTLGMideDGMD--IMEKVKEITEQQK--KKEEEEKIKAEVREdivkEEtk 76  southern house ...
Q17PN1         1 MTARSKSRRdKNNRIRRAKNKVKELKKLKKTLGLideDGMD--IMEKVKDITEQQK--KKEEEEKIKQEAMEeiirKEtn 76  yellow fever mo...
ETN59585       1 MTARSKKRRnKNNAIRRAKNKGKELKKLKKTLGLideDGME--LMDKIKDITEQDK--KEEELEIVKKEAMEdivkREtk 76  Anopheles darlingi
Q7PNZ0        79 a-taKREKFITVVnpkTNvKHlyNVKTKRDQFGQYPAWYNPRKERKKQMVREGKdaRRKE 137 Anopheles gambiae str. PEST
XP_009014417  65 ----AVTVVNVEMddtTKcKKvyNKKTLRDEHGQYPVWMNKRKIVKNKLKNKKIkrIKRl 120 Helobdella robusta
XP_011267025  74 ----ITDQEQMEVekiEN-ARvyNKKTLRDQYGNYPVWMNRRKVLKHKKGRAKMqkASKV 128 Florida carpenter ant
XP_011051019  77 ----VTGEEQMEV---EG-ARiyNKKTLRDQYGNYPVWMNHRKIVKHKKGRARTkkTDKi 128 Panamanian leafcutter ant
XP_012063967  78 ----VIGEEQMEI---ES-TRiyNKKTLRDQYGNYPVWMNHRKIIKHKKGRARTkkTSKT 129 Atta cephalotes
Q9VZC8        79 --slEKGEKVKVTnenTGvEHifNSKTLKDQYGNYPAWFKKKKTAKRLRKKQHSqkKNFK 136 fruit fly
EDV95624      79 --slEKGKEIFQVnekTGvEHvyNSKTLKDQFGNYPAWFKKKKTAKRLRKKQHAqkKNFK 136 Drosophila grimshawi
EDS41626      77 d-tvDHNEYIEIVhpeSKvKHrhNTRTKQDQFGQYPVWYNARKEKRKQLLRDGKikKKRG 135 southern house mosquito
Q17PN1        77 elglETEEYVEVEhqeSKvKHkyNAKTKRDQFGQYPVWYNARKERRKQLLIEGKikKKRG 136 yellow fever mosquito
ETN59585      77 e-tvDPNKYVEIVnpkTNvKHvyNEKTKRDQFGTYPVWYNAKKEQRKQKMREGKitRKRQ 135 Anopheles darlingi
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