Conserved Protein Domain Family
G8

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pfam10162: G8 
G8 domain
This domain is found in disease proteins PKHD1 and KIAA1199 and is named G8 after its 8 conserved glycines. It is predicted to contain 10 beta strands and an alpha helix.
Statistics
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PSSM-Id: 401970
View PSSM: pfam10162
Aligned: 151 rows
Threshold Bit Score: 68.4616
Threshold Setting Gi: 0
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q3SUQ8           122 AQSMVIENGGTVVAg-S------QRQPYGNygGVLTIHLYgadrnaSGPALGALCRTA------------------Q--- 173  Nitrobacte...
XP_002507739    4964 TDVVYVPPGTTLAV--Dvar-adVRFWIVD--GTLTV-PPda---pDEVVIAAESIMV------------------Ng-- 5014 Micromonas...
jgi:Niako_4970    49 NDAPVIAAGNTVIV--Dkd--vtVSGMHVV--GKLIVDPTr-----AVVISSSKNILV------------------Tg-- 97   Niastella ...
wustl:cce_2089    82 NADVVIAQGVEVFY--DqesdarIHTVRVD--GSLAFSQN------TDTQLIVDYIAV------------------Snt- 132  Crocosphae...
ASGPB:GKIL_0476   59 GDNVVIPSSRSVTY--NsnsqinLHTLSVF--GSLKFSTQ------SSTYLGVGLLKIgdnatvdktascngseptKat- 127  Gloeobacte...
WP_012909350      59 GDIVLVHSGHEVLY--DvvskevIRSIHVS--GTLRFSVE------CNTRLEVGLLRVeagdqile---qgfdcspTaas 125  Pirellula ...
Q22PA4          2648 NSTLWIPCPWEVVV--Dqdl-tkYTQIIVE--GNLRIDPT------KNVNIQANGIWL------------------Kg-- 2696 Tetrahymen...
Q22PG1          2668 NSTLYIPCPWEVVV--Dqdi-tqYTQIIVE--GNLRVDPT------KNINVQANGIWL------------------Rg-- 2716 Tetrahymen...
XP_001019841    2678 ATTLVIPCPWEILV--Dqdl-tqFSQIIVQ--GNLRIDYT------QNINISADAIWL------------------Kg-- 2726 Tetrahymen...
XP_011479327     392 NYTIYLHCDDRCELylSnss-rpEDQVQIA--AQPRY-VS------NYYTLDSQKSKV------------------L--- 440  Japanese m...
Q3SUQ8           174 ----------------NTDTGpc-----gIP--TSAWRdnGKTKLALPGGvsdffyrygplhgdgkcsDGSVWSSTSPCD 230  Nitrobacte...
XP_002507739    5015 ---------------gKLRVG--------GEfaTHPKK--KTVTFELRG---------------------ERGS-VSIAG 5047 Micromonas...
jgi:Niako_4970    98 ----------------QWQMQ--------------PAKlsIIQTLRFTG-------------------------IDEDKM 122  Niastella ...
wustl:cce_2089   133 ---------------gTLEMG--------TE--FNPIQ--AQANIIFAPVd----------------pNNPEIDTTWDPH 169  Crocosphae...
ASGPB:GKIL_0476  128 --------------sgSLNIG--------LP--GAPLPagVTATIKLVA----------------------------YSD 155  Gloeobacte...
WP_012909350     126 aqhdhgkketsgakraALLIG--------TP--EMPIPtkFRALIRLHA----------------------------IEG 167  Pirellula ...
Q22PA4          2697 ----------------GLFIAeg-----sTP--GSPYT--YNLNIQLNGNq----------------dQPTQFVIDPLVD 2735 Tetrahymen...
Q22PG1          2717 ----------------GMFIAeg-----aTP--GTPYT--NNLTIILTGDr----------------dQQTQFLVDSQLD 2755 Tetrahymen...
XP_001019841    2727 ----------------GLFIAeg-----aTA--GSPYT--KKLTIKLTGNr----------------dQQTQFIVDNTIE 2765 Tetrahymen...
XP_011479327     441 ----------------SLEKGkpyymellHQ--EYAVV--ASINIGLFRGd----------------sSFTKDQTDDAVN 484  Japanese m...
Q3SUQ8           231 DSQdKqvgyfgykVL--AVs----yGGSLELWGakgscnsmgcsnPQLHPSWTRLD 280  Nitrobacter winogradskyi Nb-255
XP_002507739    5048 AGP-R--------SI--VAi-----dGEVLLRGh-----------AAAT-EWSTLA 5075 Micromonas commoda
jgi:Niako_4970   123 VGS-GmdmissdiGL--WVm----gAGQLQLQGq------------RKT-SWTNat 158  Niastella koreensis GR20-10
wustl:cce_2089   170 QIS-R--------GL--VAg----dGAKVSIFG------------KEKT-GYVTla 197  Crocosphaera subtropica ATCC 51142
ASGPB:GKIL_0476  156 FSS-S--------DApgIIv----cGGRLDLHG------------QPLKKTWTRLS 186  Gloeobacter kilaueensis JS1
WP_012909350     168 TDA-K--------SWpaIVc----cGGRMEIHG------------APMKRTWTKLT 198  Pirellula staleyi
Q22PA4          2736 VGN-K------------VIl----nTGNFTLIG------------NPPSTTYTQLA 2762 Tetrahymena thermophila SB210
Q22PG1          2756 VGN-K------------VIf----nTGNFTLLG------------NPPATTSTRLA 2782 Tetrahymena thermophila SB210
XP_001019841    2766 VGN-K------------VIl----nTGNFTLLG------------NPPASTVARLT 2792 Tetrahymena thermophila SB210
XP_011479327     485 EVQ-K--------II--ATyeafdeeqVITFNS------------WPADvkavqev 517  Japanese medaka
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