Conserved Protein Domain Family
MMtag

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pfam10159: MMtag 
Kinase phosphorylation protein
This is a glycine-rich domain that is the most highly conserved region of a family of proteins that in vertebrates are associated with tumors in multiple myelomas. The region may contain phosphorylation sites for several protein kinases, as well as N-myristoylation sites and nuclear localization signals, so it might act as a signal molecule in the nucleus.
Statistics
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PSSM-Id: 401967
View PSSM: pfam10159
Aligned: 67 rows
Threshold Bit Score: 74.5284
Threshold Setting Gi: 209879271
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002141076  14 GVRGGYe---RFNWTSLKSIPTSerEHYLGQSMQVGIatrgGKFYRH---DWYYKGGDIRRtIDRstisdkmgsnknvat 87  Cryptosporidium...
Q23R95        11 GTRGGRd---QFKWDDVRQMSHKdrEQYLGQSAMMGFldkgGKWRKK---DWYTKNVDDEDeEDE--------------- 69  Tetrahymena the...
EGR27065      11 GVRGGRd---QFKWDNVRQMTHKdrEQYLGQTLKIGFldkgGKWRKK---DWYLKSKG---------------------- 62  Ichthyophthiriu...
A0BFX6        12 GCRGGHd---QFNWESLRTMKYHdrEQYLGQTTIIGYldkgGKWRKK---DWYIKPEDRNGlESN--------------- 70  Paramecium tetr...
Q4MZB0        12 GTRGGRe---QFKWEDLKSHDLKdrEHYLGHSVKVGLlerkNKFYKH---DWYLKKDSKSHtDT---------------- 69  Theileria parva
EDO07930      11 GTRGGRe---QFKWEDIKNCDNKerEHYLGHSVKIGTvkykNHFYKH---DWYLKNDNKATeG----------------- 67  Babesia bovis
EKG21064      11 GSRGSQaigdNVDVEGIRSSNHR--ENYLGHSILAPV----GRSERRrdqLFWARDKPSANvDED--------------- 69  Macrophomina ph...
EOD45595      11 gsrgsaaigdNVDVENIRNSNHR--ENYLGHSILAPV----GRSERRrdqLFWARNNAAIDvEDE--------------- 69  Neofusicoccum p...
XP_002175474  10 GTRGGQg---LFDWENVKKDHQR--ENYLGQSLYAQT----GRWAKGkdlEWWSKGKTTIAeSSArps----------er 70  Schizosaccharom...
O14256         7 GTRGGQa---QFQWEEVRNDKQK--GRYLGQSIYAAS----GRWAEGkdlEWWSKGRTTQSaINSens----------dk 67  Schizosaccharom...
XP_002141076  88 sNIKDEKLLVKQYEDQYISKLLG 110 Cryptosporidium muris RN66
Q23R95        70 -KIKQERQKIIENDQKRIRIALG 91  Tetrahymena thermophila SB210
EGR27065      63 -QQQNEIDEIQSQDQKRIRIALG 84  Ichthyophthirius multifiliis
A0BFX6        71 -QLDDEFKRAKEEDERRIRIALG 92  Paramecium tetraurelia
Q4MZB0        70 -LEEDEAELTRLYEQEIMQEML- 90  Theileria parva
EDO07930      68 -DPNEELQLIKLYEDELMLEMLG 89  Babesia bovis
EKG21064      70 -ELRQEFKEAQIRERRALNEALG 91  Macrophomina phaseolina MS6
EOD45595      70 -EIKQERKEAQIRERRALNEHLG 91  Neofusicoccum parvum UCRNP2
XP_002175474  71 dEAKREIEEIKRREQELLSQMIG 93  Schizosaccharomyces japonicus yFS275
O14256        68 eKYKKEILEIKEREQRMLAEALG 90  Schizosaccharomyces pombe 972h-
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