Conserved Protein Domain Family
RLL

?
pfam10036: RLL 
Putative carnitine deficiency-associated protein
This family of proteins conserved from nematodes to humans is of approximately 250 amino acids. It is purported to be carnitine deficiency-associated protein but this could not be confirmed. It carries a characteristic RLL sequence-motif. The function is unknown.
Statistics
?
PSSM-Id: 401864
View PSSM: pfam10036
Aligned: 42 rows
Threshold Bit Score: 135.526
Threshold Setting Gi: 74863376
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
jgi:MICPUN_59197  14 ALGYAKGVpALALDDRAFREFIVWLEDTKIRAMPMDARG----------PLRAVDAPAaaWNSAFASLVAETG------- 76  Micromonas ...
CAP22292           8 GVEYDRDY-VNFDDDTEIRRLIATVEEVHLKRRGENWAA----------QMLDESDVQk-WTAELEQYFRDFG------- 68  Caenorhabdi...
Q553E8             9 ILNYPNKDsLNLNEREQFISVISYL-LEKL--YNSSDIS----------ELLNVTDE---WENQFKNFISQKQ------- 65  Dictyosteli...
XP_003283584       9 ILKYPKTE-LNIEEKEQFISVVNYL-FEKIFNSNNVDLS----------LLMNVTDE---WENQVKSIIAQHQ------- 66  Dictyosteli...
EFA86122          15 ILKYPKPQyINLEEREEFINVVIYL----LETYLSKSSSsvgeestldlQLVSVTDT---WEDSFKKYLNENH------- 80  Heterosteli...
EGG21175          35 LLKYQKPQyVNIAEREEFIDLVKFL----LGKYGDDQHSk--------qVVQDTSDQ---WEELLIKYLKNIK------- 92  Cavenderia ...
ESS28419          30 ALACAMLEgERQADWEWTRDVVVWMEEEKIRLYPRHKRD----------AMRVVSDKHk-WWTLMLQYCRDLEvqldgeg 98  Toxoplasma ...
XP_002259125      10 LLNYKPVD----IGKDEFYYMILKLEEEKIRLYKPKERE----------KINYTKEKN--YIEHILKYLKKLN------- 66  Plasmodium ...
XP_004349212      10 ALDYVRAPaFNVDDEHEVRQLIAWLEDTRIRLYKLEDRA----------LLRDVKSDT--WPAAGQKYLDDIG------- 70  Capsaspora ...
XP_004993698      13 ALRHPLAQsFDHQDEGAFRNLVSALEDSTIRFYKMEERG----------PLRDIQSDT--WSDTFQKYLEDME------- 73  Salpingoeca...
jgi:MICPUN_59197  77 --CEldVDDA------AQTPrVFDHLLEQAVALDYRD------------NA-----------DDFGAVVKdlklasigaa 125 Micromonas ...
CAP22292          69 --APd----------gCSRAaAVDYVLSAAVEKIYEQ------------KG-----------GDDELSSArlk------- 106 Caenorhabdi...
Q553E8            66 --IPinVDNLtd---iKEKEkVVTIFTNFLIKNQYKE------------NV-----------EQIHETKYkclqrykle- 116 Dictyosteli...
XP_003283584      67 --LPiqTLNLad---tKDKElLLEKLTNLAIKRVYKD------------NS-----------EQIHETKYkclqrykle- 117 Dictyosteli...
EFA86122          81 --CTlkIDNLli---lEQKQqALEWLTTLAIKSSYKD------------NS-----------DQIHETKYkclqklklql 132 Heterosteli...
EGG21175          93 --SPltIVDTqqlndeKEKEkVLDWLTMISVKVFYKS------------NA-----------DQIHETKYkclqkmklk- 146 Cavenderia ...
ESS28419          99 paPPctPENLag---------lLDVLSSVAIADIYED-------------AlegselpidssSPLNALEKkaasvs---- 152 Toxoplasma ...
XP_002259125      67 --INvrNVNKtnihevGVRTyILNSLATLALIDEYKDlvgydqscgeqcDN-----------RNYENGKDalnggtahha 133 Plasmodium ...
XP_004349212      71 --CP--GETR------ASNPtMVDWLLNHAVNLEYAD------------QH-----------ETSDKASAatagad---- 113 Capsaspora ...
XP_004993698      74 --CP--FASKdwrgndSHRYlVVDWLLGRAVALDYHD------------NA-----------DTFNSESAmar------- 119 Salpingoeca...
jgi:MICPUN_59197 126 -----------------ppppkrqktsAGGVQGAGEREDDAPRprmRGLTDPSLVSALDELAAVLRVEIPa-----GSGV 183 Micromonas ...
CAP22292         107 ------------------------sevEKVLEAHKDSQNPLNR---LDYTSPKFAENARALCSILGISAHh-----PDPK 154 Caenorhabdi...
Q553E8           117 ---------------------------------------------nvnfdennLTEAVHSLAKLFNYDIKp----tDVHY 147 Dictyosteli...
XP_003283584     118 ---------------------------------------------nikfdekaLVEEILNLAKLFKLNVEl----gDAHY 148 Dictyosteli...
EFA86122         133 --------------------------------------------lsfdstpedLKAAIIKLATLFNIPIS-------DSL 161 Heterosteli...
EGG21175         147 ---------------------------------------------nfdcsqedLKESITKLATLFNIPSG-------GDL 174 Cavenderia ...
ESS28419         153 ----------------------svqrkRSEQTHADGIAEDLQA----------LRQPLNSVLARMHLPLLqenae----- 195 Toxoplasma ...
XP_002259125     134 gqhraddsanlqnqyivanffelnylnQAELEEQRKRRDNLRV----------LNEQINEIFKKCDIPLLvcndqdGDKW 203 Plasmodium ...
XP_004349212     114 ----------------------gssamDTTPDAPALQAYHVPAsllMDT---AVRKVLNGIAAALQLPPT------DNPL 162 Capsaspora ...
XP_004993698     120 ----------------------------------------gkAsvgIDVHSHEARAALKELAKLLQLPLV------EDDN 153 Salpingoeca...
jgi:MICPUN_59197 184 eASADacvaAVERFIAPFWSkveeaerNAGDGKEGRGDERWNlsp-----------------------------sdFPSG 234 Micromonas ...
CAP22292         155 -ILMK----AACLYISENLS-------EDVIAEETEEvlkkkk---------------------------lldikdFPIG 195 Caenorhabdi...
Q553E8           148 tALLS----MIVRVAERKFNdvpslikDEEERKKKLETTTTTtttstttnnnndnl-------ndnskneivnnniFPLG 216 Dictyosteli...
XP_003283584     149 tTLLS----MIVRIAERKFYdiptilkEEEDKKSKEAttetntnsnnnnl-------------ndnstnevvnnniFPLG 211 Dictyosteli...
EFA86122         162 tQMLH----AIVRIAERKFTsnivgnlKSSTSGVPTTKTTTTttttttitnttkatted-keyiktinteivnnniYPLG 236 Heterosteli...
EGG21175         175 tQLLH----SIIRIAERKFVglpelkdDKNIEQDNTDNNNNNnttsttsttstakpnpipaitvvtskggkvndevYPLG 250 Cavenderia ...
ESS28419         196 ----ngeivSAVKAVAMRLK--------------------------------------------------------APTG 215 Toxoplasma ...
XP_002259125     204 mYLIQ----SALHAIKEKLKkktktnn-------------------------------------------phyeslFNFN 236 Plasmodium ...
XP_004349212     163 -ELLR----AVSALVEDRLS-------PAAVAEAQSPPEARAatilds-----------------------idlkhVPLG 207 Capsaspora ...
XP_004993698     154 -LMWR----AVAKRVARKFS-------PEAITAARDAQQevvdr---------------------------htleeMPLG 194 Salpingoeca...
jgi:MICPUN_59197 235 -VALgfdedgdggCSAAATAAVNV-----------------LRALHVNDLRVLQSAVDALLVQMQEYTSDPKTDSRLGRV 296 Micromonas ...
CAP22292         196 mVAP---------KNGAVHFSARL-----------------LRLISLKQLRDVSKMINETLVEIQNLTMDMSKKANYEQV 249 Caenorhabdi...
Q553E8           217 -FDF---------KDDKMNSAATI-----------------LRLLYVSDLRELQNKINQVLSIVQNYTANPETNFKLAVV 269 Dictyosteli...
XP_003283584     212 -FDF---------KDDKINSAATI-----------------LRLLYVSDLRELQNKINQVLAIVQKYTADPQTNFKLAVV 264 Dictyosteli...
EFA86122         237 -FDL---------QNEKMNSVATI-----------------LRLLYVSDLREIQSKINQVLAIVQNYSADPQTNFKLGVV 289 Heterosteli...
EGG21175         251 -FDL---------HNDKMNTVATI-----------------LRLLYVSDLKEVQNKINEVLALVQTYTADPQTNFKLGVV 303 Cavenderia ...
ESS28419         216 -SEQ---------GDEILQDMAVAcplpvensaffkafvcgLRALHVESLRETQAEINQLIEALQALIADPVTDNRLGRV 285 Toxoplasma ...
XP_002259125     237 -ISF---------TNSNLKDFAYI-----------------TRYLLNSVLKERETHLKGVLNDIQMLTYNPVIDIRQGKV 289 Plasmodium ...
XP_004349212     208 -FST---------NDALLDEAAKI-----------------LRLLHIGELRKLQTSVNELIVSVQGLTADPKTDSSLGAV 260 Capsaspora ...
XP_004993698     195 -FST---------GDAALDDAAKV-----------------LRLLHVSDLRDLQTRVNELITAAQNVTADPKTDSSLARV 247 Salpingoeca...
jgi:MICPUN_59197 297 G 297 Micromonas commoda
CAP22292         250 q 250 Caenorhabditis briggsae
Q553E8           270 G 270 Dictyostelium discoideum
XP_003283584     265 G 265 Dictyostelium purpureum
EFA86122         290 G 290 Heterostelium album PN500
EGG21175         304 G 304 Cavenderia fasciculata
ESS28419         286 G 286 Toxoplasma gondii VEG
XP_002259125     290 G 290 Plasmodium knowlesi strain H
XP_004349212     261 G 261 Capsaspora owczarzaki ATCC 30864
XP_004993698     248 G 248 Salpingoeca rosetta
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap