6SWY


Conserved Protein Domain Family
Vac_ImportDeg

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pfam09783: Vac_ImportDeg 
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Vacuolar import and degradation protein
Members of this family are involved in the negative regulation of gluconeogenesis. They are required for both proteosome-dependent and vacuolar catabolite degradation of fructose-1,6-bisphosphatase (FBPase), where they probably regulate FBPase targeting from the FBPase-containing vesicles to the vacuole.
Statistics
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PSSM-Id: 401655
View PSSM: pfam09783
Aligned: 80 rows
Threshold Bit Score: 138.815
Threshold Setting Gi: 430813805
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6SWY_4              122 YLRPRMQFTGYQ------------ISG----YK-RYQVTVNLKTVDLPkkdctslSPHLSGFLSIRGLTN---QHPE--- 178 Saccharo...
EEA27599            447 HQS---------------------QSS----KHeLWPVKVTIHSVDYS-------TMTLSGTMEAYNIPD---KTSPtrd 491 Talaromy...
EHA19068            316 YTTTGRRYLANNiy--------hlGGG----KDeNWPVKVTIHSINPD-------DMTLSGTMEAYNIPD---KTTPahd 373 Aspergil...
Q0CTA5              393 YTSSGRRYLANNiy--------nlGAG----KDeNWPVKVTIHNVNEH-------DMTLSGTMEAYNIPD---KTSPshd 450 Aspergil...
WGS:AFWA:PNEG_01203 182 WLKSGSIFQGVQnfpgqpsiflseSSH----IRdERKIKVIIQDINFS-------KMSVSGQIEMFNASDvdfNNSS--- 247 Pneumocy...
Q9UT04              350 WLRSGSVFRGLQfggvqsisglppLTN----PKeRWIVDVSIHVVDYK-------RRALEGQLNAQARSSd--PSST--- 413 Schizosa...
XP_013021433        338 WLRSGSLFQGSQfegchsisglssNVN----LKdRWIVDVSIHLVDYK-------RLQLEGQLDAYPHNPd-sRSSA--- 402 Schizosa...
XP_005848565          4 FLRPGQSFEGGQrv---------aHHHgaipKQeTWEVKAVIQHYDPA-------KGYVAGTMEGGNVPD---MPAP--- 61  Chlorell...
XP_002957890         77 FLFPGRSFTGQQ------------RLSsphrQQeDWAVTATIYSCDLS-------RGRVTGSMVAQNSPL---AKRP--- 131 Volvox c...
CUT99143             23 CIHPGAHFVGSQ------------ISR----FK-KHAVDVSFLTVDLA-------AKTLCGFLRVDKANN---DSETfen 75  Echinoco...
6SWY_4              179 ------ISTYFEAYAVnHKe-LGFLSSswkdepvLNEFKA--TDQTDLEHW------INFPSF-RQlFLMsqknglnstd 242 Saccharo...
EEA27599            492 ----ahIITFLEGEIVdLNa-HSLETT---------SFQA--DADIDCTYW------RELRPF-RGlS------------ 536 Talaromy...
EHA19068            374 ----ahIVTYLEGEIIdFNk-HTLETK---------NFKA--DAEIDSTYW------RELQPF-KNlS------------ 418 Aspergil...
Q0CTA5              451 ----ahIITFLEGEIIdFNr-HTLETK---------NFKA--DAEIDSTYW------RELQPF-KNlT------------ 495 Aspergil...
WGS:AFWA:PNEG_01203 248 ------IIIWWNGEIVdFvgyYNLLAVk-----rGIAW------KTDVAYW------RKLEPF-KGm------------- 290 Pneumocy...
Q9UT04              414 ------ISTAWTGEILdFsekLNFATE---------KWSA--PLEIDVCYW------RKLAPF-QNm------------- 456 Schizosa...
XP_013021433        403 ------ISTAWSGEILdFsesKNFATE---------KWSA--PLEVDVCFW------RKLSPF-QSm------------- 445 Schizosa...
XP_005848565         62 ------VTTFFEGEVIdNRn-FTFFTA---------DWDA--CADTDFLHW------SKFGPF-RQlHAQvvrhg----- 111 Chlorell...
XP_002957890        132 ------IVTYFEGEIIdNi-nHIFWTG--------NKWGAcpSRETDLRYW------SRCPGFtSAlRAAvqqhh----- 185 Volvox c...
CUT99143             76 ggdgkaVTSFFNGEIIsRl--FPFITG---------KWGA--SVETDTNHWnelnvmARFPNYyrdn------------- 129 Echinoco...
6SWY_4              243 dngttnaakklppqqlpttpsadagnisrifsqekqfdNYLNE---------------RFIFMKWK-------------- 293 Saccharo...
EEA27599            537 --------------------------------------DDQMTknllsktwvtdelnkNWILMRWK-------------- 564 Talaromy...
EHA19068            419 --------------------------------------DEEMTrklvsrkwvteqlskQWILMRWKgefrlreslqnktn 460 Aspergil...
Q0CTA5              496 --------------------------------------DEEMTrnlvsrkwiteelsqGWILMRWK-------------- 523 Aspergil...
WGS:AFWA:PNEG_01203 291 --------------------------------------DDYEFfnllfakdkitdicsKYIFMRWK-------------- 318 Pneumocy...
Q9UT04              457 --------------------------------------DTNTFletitnpkklykicqKYIFMRWK-------------- 484 Schizosa...
XP_013021433        446 --------------------------------------DSDTFfdtitdgkklsrvcrEYIFMRWK-------------- 473 Schizosa...
XP_005848565        112 ----------------------------------grcpALAAH---------------PYVYMRWK-------------- 128 Chlorell...
XP_002957890        186 ----------------------------------grapQLGTC---------------PHVFMRWK-------------- 202 Volvox c...
CUT99143            130 ----------------------------------fdysQLENF---------------DHVYMRWK-------------- 146 Echinoco...
6SWY_4              294 ----E-KFLVP------DAlLMEGVDGASYDGFYYIVHDQVTGNIQGFYYHQDA-EKFQQLELVPS 347 Saccharomyces cerevisi...
EEA27599            565 ----ErCFITPt-----DA-----RQGLTISGFYYISLRRGTGEIEGLYYDPGS-SPYQQLSLKPE 615 Talaromyces marneffei ...
EHA19068            461 iralErCFITPt-----DS-----RQGLTISGFYYISLNRQSGNIEGLYYDPGS-SPYQQLSLKPE 515 Aspergillus niger ATCC...
Q0CTA5              524 ----ErCFITPt-----DS-----RQGLTISGFYYISLHRESGHVEGLYYDPGS-SPYQQLSLTPE 574 Aspergillus terreus NI...
WGS:AFWA:PNEG_01203 319 ----EsEFIGP---------FMFE-SDFATSGSYFCCLRRNDGFIEGYYFDPSL--SCQYISLYpk 368 Pneumocystis murina B123
Q9UT04              485 ----DmLILKD---------QTDT-SESRITGFYFCCLCRENGYIQGYYYDPKHaFCSQPLNLFPE 536 Schizosaccharomyces po...
XP_013021433        474 ----DiVYLGN---------QIDR-SNHKISGFYFCCLSRTTGDVQGYYYDPHNtACSQPLNLYPk 525 Schizosaccharomyces cr...
XP_005848565        129 ----E-QFFV----------RGSE-CRLTIAGFYYLAINRASGKVTGYYFDPSS-SPDQKLELTPV 177 Chlorella variabilis
XP_002957890        203 ----E-CFFV----------DVPQDCPLTITGYYYLSLDRQSGSIGGYYHDARS-APLQVLQLQP- 251 Volvox carteri f. naga...
CUT99143            147 ----E-KFILPdpnrtsDK-KPST-------GFYYICLQKSTGELTGYFHNKTE-RRVHRIYLmyd 198 Echinococcus multilocu...
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