Conserved Protein Domain Family
DUF2048

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pfam09752: DUF2048 
Abhydrolase domain containing 18
The proteins in this family are conserved from plants to vertebrates. The function is unknown.
Statistics
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PSSM-Id: 370661
View PSSM: pfam09752
Aligned: 8 rows
Threshold Bit Score: 427.62
Threshold Setting Gi: 122155611
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q4V7A8     16 TKLFIRGWGR-----------PEDLKRLFEFRKMIGNR-ERCQNLVSSDYPVHIDKVEEQSDCK-----ILDGHFVSPMA 78  Norway rat
Q8IQI5     15 TRFFEKGWGK-----------PENLRKVFQFRKVISSR-ESCFKLVPRDYPVEITKKEIGAEST-----LIEGQFKTPME 77  fruit fly
Q18852     26 SQLFTKSWGH-----------PDVIKQMAKYRRDVMSKrLVMDYVKELNPKIDIVKKYSKNGVT-----SYEGFFASPHA 89  Caenorhabditis ele...
EDO48923   21 SKFFTKGWGE-----------LDAVKRLFDFRLEFKER-EKCASLVPSSYPVHLDKSWKRDSYY-----MAEGHFLSPVA 83  starlet sea anemone
Q00VQ9     23 TRFFHEGWGDlahakavalrsLEYFDSVALSSGQLERGdVQDASRTRSGIEIDWGRDVDADDGYgvdviRQDASFESP-- 100 Ostreococcus tauri
Q6H7Q9     28 TPFFSKGWGGtkl-----dllEKMVKQLFP-EARCQNW-------PPTAVQPMWKTVWETKSSC-----LREGVFRTTCD 89  Japanese rice
Q8RWA3     31 pPFFSRGWGGpnl-----ellERMVQRLFPLEVQGQNW-------PPPLVRPVWRTVWETKTAT-----LREGVFQTPCA 93  thale cress
XP_314274  16 TKFFCKGWGK-----------PENLERLFAFRKIISNR-AACSQLVPRDYPVEITKEEIHSDCK-----ILEGKFISPLE 78  Anopheles gambiae ...
Q4V7A8     79 HYVPGIMPIESVIARFQFIVPKEW-NSRY---RPVCI-HLAGTGDHHYWRRRTLMARPMIKEaRMASLLLENPYYILLKP 153 Norway rat
Q8IQI5     78 LHMPGVVPEESQQAHFQLLIPNKWkNEKH---KPICI-HLAGTGDHFFWRRRNFIAKPLLKDaNIGSIILENPFYGLRKP 153 fruit fly
Q18852     90 TLFPNHMPGNVGRAHFRAYLPQKP--------GPVCI-HLAGTGDHSYFRRHYLLVDDMLKD-GVGSILIQNPFYGDRKP 159 Caenorhabditis ele...
EDO48923   84 KYLPGILPQQSEYARFQVIIPTKWqHRNR---KPMCV-HLAGTGDHFYWRRRNFMAKPLLKEhGIGSIILENPFYGSRKP 159 starlet sea anemone
Q00VQ9    101 --FADMLPAESRRVLFARLRPGRGgDARKdgaRRVAI-LLPCTGDIDEWYRRSI-ARELLES-GVECVIPTIAYYGARAP 175 Ostreococcus tauri
Q6H7Q9     90 PRLIEALPPESHNARVAFLTPKSV--SPE---KMACViHLAGTGDHSFERRLRL-GGPLLKD-NIATMVLESPYYGQRRP 162 Japanese rice
Q8RWA3     94 DELTAALPPESRTARVAWLVPKNV--PPQ---KMACVvHLAGTGDHTYDRRLRL-GGPLVKQ-NIATMVLESPFYGQRRP 166 thale cress
XP_314274  79 IYMPGLVPDVAQNAHFQILLPLKWnDERY---KPICI-HLAGTGDHYYWKRRNLIAKPLLKEaNLGAIILENPFYGLRKP 154 Anopheles gambiae ...
Q4V7A8    154 KDQVRSSLKNVSDLFVMGGALILESAALLHWLERE-GYG-PLGMTGISMGGHMASLAVSNWPKPMP-----LIPCLSWST 226 Norway rat
Q8IQI5    154 NNQTRSNLHNVSDIFVMGGCLILECLVLFHWCERN-GFG-PLGVTGLSMGGHMASLAATNWPKPLV-----LVPCLSWST 226 fruit fly
Q18852    160 PNQFRSSLENVTDLFVMGAALIAECNHLFNWSETL-GYG-PFAISGVSMGGFMAQLAGSNSQRPIS-----IVPILAWTT 232 Caenorhabditis ele...
EDO48923  160 KDQQRSSLKHVVDLFIMGTGLILESSVLLHWCERH-GYG-PLALTGISMGGHMASLAATVWPKPLA-----VVPCLSWST 232 starlet sea anemone
Q00VQ9    176 RGQWRHVIRTVSEAKIQLSVTPVEMMEIARAVMEEsGPGtELCLAGVSLGGTMSALTACALARNAVdadstSVCCIAAAN 255 Ostreococcus tauri
Q6H7Q9    163 SMQHGSKLQCVSDLLLLGKATIDEARSLLYWLQNEaGYG-KMGICGLSMGGVHAAMVGSLHPTPIA-----TLPFLAPHS 236 Japanese rice
Q8RWA3    167 FLQCGARLLCVSDLLLLGRATIEESRSLIHWLDTEeGFG-KMGVCGLSMGGVHASMVGSLHPTPVA-----TLPFLSPHS 240 thale cress
XP_314274 155 KEQRASSLQNVSDIFVMGGCLVLESLVLLNWCERN-GYG-PLGITGLSMGGHMASLAATNWPKPLV-----LVPCLSWST 227 Anopheles gambiae ...
Q4V7A8    227 ASGVFTTGVLSKSINWRELEKQyYTQTVYEEEIihmleycgtdsfkmghefmkhfpsnedkltnlnlvsrtlnldmr--- 303 Norway rat
Q8IQI5    227 ASAVFTTGVMSQSINWDMLETQyFSDGQYRERLskmvtviddafsagqsfiqnfnqslqelkedisdtrkihatensntc 306 fruit fly
Q18852    233 ASPSYTEGAISPAVNYSLLQKQ-LEDPHYVDK------------------------------------------------ 263 Caenorhabditis ele...
EDO48923  233 ASCVFTEGVMRKSLPWDFLKQQ-LEDDNYRETLidaagirdevtreclftnkgsmsgvksipvqdltsq----------- 300 starlet sea anemone
Q00VQ9    256 DCTPYTDGSIETRLAWDVLCEQ----------L----------------------------------------------- 278 Ostreococcus tauri
Q6H7Q9    237 AVVPFCDGLYRHATAWDALRKD---------------------------------------------------------- 258 Japanese rice
Q8RWA3    241 AVVAFCEGILKYGTAWEALREE---------------------------------------------------------- 262 thale cress
XP_314274 228 ASSVFTEGVMSHSISWDVLETQyFADGNFRERLskmvtvvddafvagkhfiqnfnqsveelrqdidetsdlvcgdpstdv 307 Anopheles gambiae ...
Q4V7A8    304 ------------------------------------------------------------dqvvspkhaechhsgkasis 323 Norway rat
Q8IQI5    307 gdkyetqgi---------------------------------------cpqedssiflskslkntkldsenltidakdal 347 fruit fly
Q18852        --------------------------------------------------------------------------------     Caenorhabditis ele...
EDO48923  301 --------------------------------------------------------------------lnvdnhqldmch 312 starlet sea anemone
Q00VQ9        --------------------------------------------------------------------------------     Ostreococcus tauri
Q6H7Q9        --------------------------------------------------------------------------------     Japanese rice
Q8RWA3        --------------------------------------------------------------------------------     thale cress
XP_314274 308 nltvirettpeheqkknlihinrsnalslsepllnkllsnvrceltqeeidelnvkihlalkrhneelqaegggllppra 387 Anopheles gambiae ...
Q4V7A8    324 atskgqllqdtakverlnqtlttNKSCFASYNPQSLHLLSREQRRSNlqKESLIFMKGVMDECTHVANFSVPVDPSLIIV 403 Norway rat
Q8IQI5    348 sqkvaieteetskdsgstltnlmKFILPLSAQSKTDKIDITKTNWWE--REALQFMRGMMDECTHLKNFSVPFDTSLIIA 425 fruit fly
Q18852    264 -------------------------IRRIPNQNWLDKMREMTARNGD--SEAKNMMRILMDDFTSLEFYPTPIDTSLCHV 316 Caenorhabditis ele...
EDO48923  313 iresdfdpqytphtvslerrpllSNVRDVVVNYIPPPLKKKKEQPNTicSDALRFMNILMDHATHLKNFSCPYEPKLAKF 392 starlet sea anemone
Q00VQ9    279 -----------------------ATKSDEAAAVEAAACWGGHEKGAT--KEQAREAFLEAMSELNMQALVVEKSVRSAVF 333 Ostreococcus tauri
Q6H7Q9    259 -------------------------AATLAQDVTSLTEDMAQKSGIT--IEQVRERLRSVLSLTDVTRFPVPKNPQAVIF 311 Japanese rice
Q8RWA3    263 --------------------------------------LAAQKITMT--LDEVRERMRNVLSLTDVTRFPIPKNPDAVIF 302 thale cress
XP_314274 388 aprrccwspwvrkswntsaggssSTADGAAAEEKRIPIDTTKQRWWE--REALQFMRGMMDECTHLKNFSVPYDTSLIIA 465 Anopheles gambiae ...
Q4V7A8    404 VQAKEDAYI--PRTGVR-SLQEIWPGCEIRY---LEG-GHISAYLFKQGLFRQAIYDAFER 457 Norway rat
Q8IQI5    426 VCAKDDAYV--PREGCS-SLEEIWPGAEVRY---LDA-GHVSAYVLHQKLFRSCIIEAFER 479 fruit fly
Q18852    317 FLADQDQYV--LRNQGTpTYQQLWPNVTVEM---MEGyGHVTAYLSKHDLWRRRITELLRR 372 Caenorhabditis elegans
EDO48923  393 VAATSDAYV--PHYSVEdTPQQIWPGSEVAY---VDG-GHIGASLNHMHIFRKVIKEKLDQ 447 starlet sea anemone
Q00VQ9    334 ITAKNDRFVgnTTEAIAeTLQTMATDSNGYWredFDG-GHLQFIFGRKSVIAPSIKRAFEL 393 Ostreococcus tauri
Q6H7Q9    312 VGATDDGYI--PKHSIM-ELQKAWPGSEVRW---VTG-GHVSSFFLHNDAFRKAIVDALDR 365 Japanese rice
Q8RWA3    303 VAATDDGYI--PKHSVL-ELQKAWPGSEVRW---VTG-GHVSSFILHNDEFRRAIVDGLDR 356 thale cress
XP_314274 466 VCAKDDAYI--PRDGCT-SLEDIWPGAEIRY---LDA-GHVSAYVLHQKLFRSCIIEAFER 519 Anopheles gambiae str. PEST
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