Conserved Protein Domain Family
Jnk-SapK_ap_N

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pfam09744: Jnk-SapK_ap_N 
JNK_SAPK-associated protein-1
This is the N-terminal 200 residues of a set of proteins conserved from yeasts to humans. Most of the proteins in this entry have an RhoGEF pfam00621 domain at their C-terminal end.
Statistics
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PSSM-Id: 401623
View PSSM: pfam09744
Aligned: 39 rows
Threshold Bit Score: 110.774
Threshold Setting Gi: 0
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CDS43653       46 VQAIAHRFNAEFEAVLAAgeadsgARAAIVQRLLPTVVAVLEQLDEFYKDHAAYKAEVVQLREETTSLFSQLTKEKSARR 125  Echinococcus ...
CDG24109       41 VQTMASAIYRELETMIKV------HGEDGVKTLMPLVVNVLEALDLAYLERDEQTAELEMLKEDNEQLQTQYEREKALRK 114  Caenorhabditi...
EKC20447       22 VSSLATNIYKEFERMIKK------YDEDVVKELMPLIVALLEGLDQSLSDKQEADVELELLRDDNEQLLTQYEREKQLRK 95   Pacific oyster
Q29EP6         42 VQQLAGSIYQEFERMINR------YDEDVVKNLMPLLVNVLECLDASYRINQEQDVELELLREDNEQLVTQYEREKSARK 115  Drosophila ps...
EFN78716       21 VQSLAGSIYQEFEKMIAR------YDEDVVKDLMPLLVNVLECLDISYTENQEREVELELLREDNEQLVTQYEREKQLRK 94   Jerdon's jump...
XP_025196361   21 VQSLAGSIYQEFEKMISK------YDEEVVKNLMPLVVNVLECLDLSHTENQEHEVEVELLREDNEQLVTQYEREKQLRK 94   Melanaphis sa...
EFX78867       20 VQTLARNIYQEFQRMIQK------YDEDVVKDLMPNIVNMLECLDLAYTANQEHEVELELLREDNEQLVTQYEREKQLRR 93   common water ...
XP_001639102   27 VSNLANSIYSEFERMIQK------YDQDVVSGLMPLMVSVLEQLDSAYGDNNEQLVELEILSDDNEQLITQYEREKQLRK 100  starlet sea a...
XP_011677854   25 VQGIAASIYREFEQMIKT------YDEDVVKELMPLVVNVLETLENTVTENQEHEVELELIKDDNEQLITQYEREKQLRK 98   purple sea ur...
XP_026696466   33 VQAMANSVYGEFKRMMGT------YGEEVIKELMPLIVTILETLDRSLSECNANAVEVEMLKDDNEQLATQYERERQLRR 106  vase tunicate
CDS43653      126 DTEDLLMRMEDQFESERKILNEALAQNETQIRRLEiksknvEEQLARMEQKEQESLKENSKLHERINELLRSHAELNDSL 205  Echinococcus ...
CDG24109      115 QTEQKYIEIEDTLIGQNKELDKKIESLESIMRMLElkaknaTDHASRLEEREVEQKLEFDRLHERYNTLLRTHVDHMERT 194  Caenorhabditi...
EKC20447       96 GTEQKYLEMEDAVEGEKKSMQDKLESLESVVRMLElkvknsADHVSRMEEKEVDLKKEYTKLHERYTELFRTHMDYMERT 175  Pacific oyster
Q29EP6        116 QSEQKLLEAEDLAEQENKELATRLESVESIVRMLElkhknsLEHASRLEERETDLKKEYNKLHERYTELFKNHVDYMERT 195  Drosophila ps...
EFN78716       95 ASDQKLLELEDVSEDERKELLSKIDSLESIVRMLElktknsHDHVGRLEEKEAELKREYSRLHDRYTELFKTHVDYMERT 174  Jerdon's jump...
XP_025196361   95 SAEQKLLEMEDYIEDEKKDYQSKIESLESIVRMLElkaknaSDHVYRLEEKEQDMKQEYTKLHERYTELFKTHMDHIERT 174  Melanaphis sa...
EFX78867       94 TTDSKLLELEDVTEEENKGLQAKVESLESIVRMLElkaknaTDHVFRLEEKENEMRKEFTKVHDRYTELLKVHMDHVERT 173  common water ...
XP_001639102  101 LAENRYLEIEDQIEAEKRNAEKDIESLEHDNRGLEariksyQDHVERLEERISEMKREYGSLHQRHSEVVQHYMERIERA 180  starlet sea a...
XP_011677854   99 QSEQKFLEYEDVNDQEKRLLQARVEQMEMSGKQTGlklknySDQISRHEYRENDMKLEYTALQKRHNEVVQKYMEYADRF 178  purple sea ur...
XP_026696466  107 HAEQQLMESEDVNEAATREIRAKADALETATRHLElkcknyTDQVERLQEREADLKREYTILHERHTEMIQSYMEHIEKT 186  vase tunicate
CDS43653      206 K 206  Echinococcus multilocularis
CDG24109      195 K 195  Caenorhabditis elegans
EKC20447      176 K 176  Pacific oyster
Q29EP6        196 K 196  Drosophila pseudoobscura pseudoobscura
EFN78716      175 K 175  Jerdon's jumping ant
XP_025196361  175 K 175  Melanaphis sacchari
EFX78867      174 R 174  common water flea
XP_001639102  181 E 181  starlet sea anemone
XP_011677854  179 K 179  purple sea urchin
XP_026696466  187 K 187  vase tunicate
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