5MSM


Conserved Protein Domain Family
Dcc1

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pfam09724: Dcc1 
Sister chromatid cohesion protein Dcc1
Sister chromatid cohesion protein Dcc1 is a component of the Ctf18-RFC complex. This complex is required for the efficient establishment of chromosome cohesion during S-phase and for loading the replication clamp Pol30/PCNA, which functions in DNA replication and repair. Ctf18-RFC loads PCNA onto DNA in an ATP-dependent manner. It may also have PCNA-unloading activity.
Statistics
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PSSM-Id: 401605
View PSSM: pfam09724
Aligned: 110 rows
Threshold Bit Score: 159.334
Threshold Setting Gi: 122045984
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5MSM_A                 15 YKLIQLTPELLDII----------------------QdpvQNHQLRFKSLDKDksEVVLCSHDKTWVLKQRKHSNTVLLm 72 
KDE06391               20 YSLLSLPASVLALLssdea-------------ttslP---HGSTLEIRGHSTD--AAVLVTPDQTYSLRGVQNSNSLCLc 81  Microb...
CCF50066               20 YHLLEIPNELLRLFdpsakpkda-----epaakkrkT---EPSRLTIKGRYDD--QAVLTTDTQTLALRAVSQSNSLLLc 89  Ustila...
GAC71379               21 YHLLEIPSELVHLFdppaqpsd------eppskkrrQ---DPSRLTIKGRYGD--QAVLTTKSQTLALRAVSQSNSLLLc 89  Moeszi...
XP_016294244           23 YHLLEIPNELLHLFdpsakkkddts-asepaakrrkT---DITRLTIKGRYDD--QAVLVTDTQTLALRAVSQSNSLLLc 96  Kalman...
XP_011391237           22 YHLLEIPNELLHLFdpsvkkqeapehatepaakkrkV---DPARLTIKGRYND--QAVLVSDTQTLALRAVSQSNSLLLc 96  Ustila...
XP_007407455           46 YLLLELPPVLLNPIkeqln-------------npsnQ---NQNQLELRGRLED--DLVLTTKDKTYSLRTIQNSNSVMIc 107 Melamp...
WGS:AAWC:PGTG_04233.3  42 YLLLDLPPELLEPVkkqlq------------ghdtgN---ADLQMELRGRNDD--EVVLTTPDKTFQLRTVQNSNSVMIc 104 Puccin...
OAW00069               42 YLLLDLPPELLEPVikrlk------------gqdeaA---GDPQMELRGRNDD--EVVLTTPDKTFQLRTVQNSNSVLVc 104 Puccin...
XP_006955787           16 FKLLELNDELVKAL----------------------D---DQKLLLFKGDGDE--DVVLCTQDNTYSLKNRMHSNSLTMl 68  Wallem...
5MSM_A                 73 refVPEQPITFDETL----------------------------LfglskpymDVVGFAKTESE-FETRETH---G-EL-N 118
KDE06391               82 satERGKKGWFELDEeegsdqegnlgsdreveeegpkrkkrkgK--------GEILIETVLHEtLELVPAV---A-KTeR 149 Microb...
CCF50066               90 sidPTPPSFSSSADAgs-------------------------sK--------PALYLRSNVTDtLELTPVV---P-RLdR 132 Ustila...
GAC71379               90 sidTDSVSSAASLEPes-------------------------tV--------SVLRLRSNVTDtLELSPVV---P-RLdR 132 Moeszi...
XP_016294244           97 sidAAPSTAEGEAGPs---------------------------K--------PALYLQSNVTDtLELAPVV---P-RLdR 137 Kalman...
XP_011391237           97 sidAAPTNNEGDQTPk---------------------------N--------AALYLRSNVTDtLELAPVV---P-RLdR 137 Ustila...
XP_007407455          108 ktiPDSININ---------------------------------L--------SSLEVLQTVNEtIEIFDVTsfpGtRLeR 146 Melamp...
WGS:AAWC:PGTG_04233.3 105 gtgSLDDENQ---------------------------------K--------LGLTVLKVIHEtIELSDVTsfpGsRLdR 143 Puccin...
OAW00069              105 gtsRLDGENP---------------------------------K--------LGLTVLKVVHEtIELGDVTcfpGnRLdR 143 Puccin...
XP_006955787           69 desTN--------------------------------------K--------DEYSIAHTFHEiLEVQKCS---P-NIdK 98  Wallem...
5MSM_A                119 LNSV---P-IYNGELDFSDKIMKRsst---kviGTLEELLENSPCSALEGISKWHKIGGSVKDGVLCILSQDFLFKALHV 191
KDE06391              150 LKELvkgS-EYRGEDGEQDRQREGtvn---kklYTFGELGSLLPASDAEIRLALTRQRIVTLDTHLRSIPTSYLLTLLPA 225 Microb...
CCF50066              133 LLGLlkaS-QYEGEEEETPRSAPNsrp---vrkYTLKQLKSIVQASPAELEAGLVHNHVIELDGYMRHLSPTWMVSVLQI 208 Ustila...
GAC71379              133 LVGLlkaS-QYQGEEEEDRRATKAarp---vrkYTPKQLRSIVQASPAELDAGLIQHHIIEMDGYMRHISPTWTVSALQL 208 Moeszi...
XP_016294244          138 LLGLlkpS-QYDGEEER-----GSakp---vkkYTLKQLKSIVQASPAELEAGLIKNHVIEMDGCMRHISPAWTVSALQI 208 Kalman...
XP_011391237          138 LIGLlkaS-QYEGEDEEQRRSTGAarp---vrkYTLKQLKSIVQASPAELEAGLIHHHIIEMDGFMRHISPSWTVSALQV 213 Ustila...
XP_007407455          147 IKELl-qPwSYSGEDEEEKRMGYMndddhsiepITFQSLSNETRASDEEIKQFLSVLNVIKLKDSLRILNLSYLAEILKE 225 Melamp...
WGS:AAWC:PGTG_04233.3 144 IKELl-qPhLYSGETNEAVRRAEDsdstdapipVSLSFLSQQIRASDSEIQDYLRQLHVIELGGSLRMISLGYLSTILSG 222 Puccin...
OAW00069              144 IKQLl-qPhLYTGETSEAERRMEDsksldvplpVTLDSLSQEVRASDSEIQDYLNQLHVIELDGSLRMISLGYLSTILSG 222 Puccin...
XP_006955787           99 IDMLlshRvLLDPTEVDNNVEERLk--------YDYDRISSEIQASDKEIRQAFTDRRIVCFNGEYRPVDPECLLRALDV 170 Wallem...
5MSM_A                192 LLMSA-MAESLDLqhLNV-------EDTHHAVgkdiedefNpYTREIIETVLN-KFAvqEQEa--eNNTWR--------- 251
KDE06391              226 LLQALpLPKYLDPtsTSAitieaedEELLEAFda-----aGdCRTEAARQVLD-WFS--TPAe--kSGWSV--------- 286 Microb...
CCF50066              209 LISHLdLHALIP---DAVp-----lQETVEALek-----vHsIRPQISNAILTqFFG--SKLp--sDPAKVa-------- 263 Ustila...
GAC71379              209 LISHLdLHALIP---DQVp-----lNETVEALqa-----mHgLRPQVVTALLTqFFG--CVNerddAIASSaadata-ti 272 Moeszi...
XP_016294244          209 LISHLdLHALIS---DSVp-----lQETVEALat-----vHeLNRQVVTALLTqFFG--TLTg--eTVA----------- 260 Kalman...
XP_011391237          214 LISHLdLHALIP---DNVp-----lQETVDALyt-----vHgLRQQVVTALLTqFFG--TRSt--kDPTRVe-------- 268 Ustila...
XP_007407455          226 IIDSS-LELGFKLdePFMi------EPLVEIVsv-----kMnISTSVLLQVLS-WYD--TRQa--sTTETPqdlsldskt 288 Melamp...
WGS:AAWC:PGTG_04233.3 223 ILKSL-DELGVGPheQFAv------GPVVDIIts-----rLdIHQAALLQILH-KFS--IDFk--iHEPYDsfdpn---q 282 Puccin...
OAW00069              223 LLKSL-EELGVGPqeQFAi------GPVIDIIts-----rLdIHQAVLLQIFQ-KIS--VDFk--iNQPYDsfdpq---q 282 Puccin...
XP_006955787          171 ILNTL---ELVDMsfNKVd-----kDELADSInk-----dHnINRDYISTVIG-WYM--NSDt----------------- 217 Wallem...
5MSM_A                252 ---LRIPFIAQWYGIQALRKYv----------------SgiSMPIDEFLIKWKSLF--PPFFP-Cdi----dIDMLRGYH 305
KDE06391              287 ---LRVKEVVREVGIVLLAQGg---------------yG--GQRLDTFLGKWKSLC--------HqfeslctPTLLTNTS 338 Microb...
CCF50066              264 ---LDTKTIVLYLGVQSLKSTa---------------rI--AIPLSDFMATWTNAClsSADFL-Thv----nLDLLSGFY 318 Ustila...
GAC71379              273 tvkLDVKAIVHFLGVETLKASa---------------rI--GLPLADFQRTWKQSClsP-DFE-Ala----qLELLSGYY 329 Moeszi...
XP_016294244          261 ---LDTKSIVHFLGVQSLKTAr----------------I--GVPLTTFMRDWHAAClsP-DFR-Ala----sLDLLSGYY 313 Kalman...
XP_011391237          269 ---LDTKAIVHFLGVQALKSTa---------------rI--EIPLSEFVHIWHESClsA-DFR-Sma----hLDLLSGYY 322 Ustila...
XP_007407455          289 tisFDINKIVTVIGLSLLLSIkptqvepm-nprnnktiQ--TTPIESFLTDWKTRI--GEPYSdQyc----sIDSLKTHS 359 Melamp...
WGS:AAWC:PGTG_04233.3 283 nasLKLQEVVNSIGLAQLLCIkptkiesnhnpkdhryiQ--KMNVESFLATWTSKL--PEGLS-Ehc----sIESLSSHS 353 Puccin...
OAW00069              283 ntiLKLQEVVNLIGLSQLLCIkptklesshnpkdhryiQ--KMNVESFLATWTSKL--PERLS-Ekc----sIESLSSHS 353 Puccin...
XP_006955787          218 --tLDSQAFVKEIGLSLLKVQs----------------R--ATAFEKFLDDWKSRS--GYELQ-Dqc----nLNLLKGYY 270 Wallem...
5MSM_A                306 FKPTDKT-------------VQYIAKSTLPMDPKERFKVLFRLQSQWDLEDIKPLI 348
KDE06391              339 IISPNAIpp----------sITYLPISHLSADPATRFSELFTLRPKWFADDLIPFI 384 Microbotryum lychnidis-dioicae...
CCF50066              319 LLSPSPVpgvalypnaasvkIQFYSRLELPADPAARFQDLFLTRAAWLAADLLPFI 374 Ustilago hordei
GAC71379              330 LLSPAPSpsvslypnpasmqIQFYSHHELPTEPAARFQDLFLTRAAWIASDLLPFI 385 Moesziomyces antarcticus T-34
XP_016294244          314 ILTPSPApgvslypnpastqIQFFSRHELPVDPAARFQDLFLTRPSWIAADLTPFI 369 Kalmanozyma brasiliensis GHG001
XP_011391237          323 ILTPAPSpsvslypnpaavkIQFFSYHELPADPAARFQDLFLTRPSWLAADLLPFI 378 Ustilago maydis 521
XP_007407455          360 IISSDQKn------------LIIVPIEKLSSEPKTRMSQLFEIRNKWKMEELERFV 403 Melampsora larici-populina 98AG31
WGS:AAWC:PGTG_04233.3 354 ILSNDQKn------------IIVIPIDKLSLEPKMRMSQLFEIQPKWKIDQIERFL 397 Puccinia graminis f. sp. triti...
OAW00069              354 ILSNDQKs------------IIVIPIDKLSLEPKMRMSQLFEIQPKWKIDEIERFl 397 Puccinia triticina 1-1 BBBD Ra...
XP_006955787          271 LIEAGQ--------------ITYFTTSSLSKNPSKRFQELFKTRQKWFSVDFIPFI 312 Wallemia mellicola CBS 633.66
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