Conserved Protein Domain Family
ETRAMP

?
pfam09716: ETRAMP 
Malarial early transcribed membrane protein (ETRAMP)
These sequences represent a family of proteins from the malaria parasite Plasmodium falciparum, several of which have been shown to be expressed specifically in the ring stage as well as the rodent parasite Plasmodium yoelii. A homolog from Plasmodium chabaudi was localized to the parasitophorous vacuole membrane. Members have an initial hydrophobic, Phe/Tyr-rich, stretch long enough to span the membrane, a highly charged region rich in Lys, a second putative transmembrane region and a second highly charged, low complexity sequence region. Some members have up to 100 residues of additional C-terminal sequence. These genes have been shown to be found in the sub-telomeric regions of both Plasmodium falciparum and P. yoelii chromosomes.
Statistics
?
PSSM-Id: 401597
View PSSM: pfam09716
Aligned: 39 rows
Threshold Bit Score: 32.2111
Threshold Setting Gi: 74881962
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
XP_002261176   1 MKFTRA-CSVFAFLLAVKLLTPECHCDHVNKkphvhsnhghgngncgvnhgnssansgnlsstgnsgnsgnsgksgnsgn 79  Plasmodium know...
Q7RL79         1 MKVPKVsALFLVFLLSVSFLPSSSLCDPNAAntkipnipnptanaqsptvsgnsie------------------------ 56  Plasmodium yoel...
CDS44379       1 MKVPKVsALFFVFLLSVCFLPSPSLCDASTGntkipnipnipnssgnaqsptvsgns----------------------- 57  Plasmodium berg...
Q7RSZ7         1 MKTTYV-SLFFIILLICGIFECKASSVDETNd------------------------------------------------ 31  Plasmodium yoel...
Q8IEU1         1 MKVSKL-VLFAHIFFIINILCQYICLNASKVnkkg--------------------------------------------- 34  Plasmodium falc...
CDS51324       1 MNTLNV-FFVFYVLYITTFFFNPCFCEDTDYy------------------------------------------------ 31  Plasmodium berg...
Q7RK90        27 MNTLKV-FFVFYVLYITTFFFNPCFCEDADYy------------------------------------------------ 57  Plasmodium yoel...
XP_001616488   1 MKATNHlSVFALFLFIIAIIPCLAVYSDIPI------------------------------------------------- 31  malaria parasit...
XP_002261684   1 MKITKL-LALFAILPIVCLCGNEEVDVISQN------------------------------------------------- 30  Plasmodium know...
EDL42975       1 MKIAKL-LALFAILPIVCLLGQEEVKAVSPS------------------------------------------------- 30  malaria parasit...
XP_002261176  80 scnspcsnvvsgnssnsvsapvsgasassaklsgpgtippaptpspvkpspkDDAGKAIDQIDDQIEKKNKKKKLCVISS 159 Plasmodium know...
Q7RL79        57 ----------------------------qtaeepnaatkvnnvpvpekkndaPVENKDIEKVNDQINAK-SKTKPLLISA 107 Plasmodium yoel...
CDS44379      58 --------------------------ieqtaetsnvatranhvpapektngaPVENKDIAKVNDKICAK-NKNKPLLISA 110 Plasmodium berg...
Q7RSZ7        32 ---------------------------------------------------pKPNNVKLTDKINSIFKNKRNGKIAAIAA 60  Plasmodium yoel...
Q8IEU1        35 ------------------------------------------------kiaeEKKRKNIKNIDKAIEEHNKRKKLIYYSL 66  Plasmodium falc...
CDS51324      32 ---------------------------------------------------sETNDNSLKNIDTAIGKK-KGKKSVAIAL 59  Plasmodium berg...
Q7RK90        58 ---------------------------------------------------sEIDDGALDSIDTAIKKK-KKRKSVAIAL 85  Plasmodium yoel...
XP_001616488  32 ----------------------------------------------------EKLDYETIKANEKIRSKSRKDELIMLSL 59  malaria parasit...
XP_002261684  31 ----------------------------------------------------DKLKKEDLDVDTKIKKHLQKRKLMMMSM 58  Plasmodium know...
EDL42975      31 ----------------------------------------------------DKLKKDDLDVDDRIRRLLQKRKLIMLSV 58  malaria parasit...
XP_002261176 160 AATALALLLGGAVG-LGIYKKRKA 182 Plasmodium knowlesi strain H
Q7RL79       108 ISAVVAIAIASALG-YGIYTKKNS 130 Plasmodium yoelii yoelii
CDS44379     111 ISAVVAIAVASALG-YGIYTKKNL 133 Plasmodium berghei ANKA
Q7RSZ7        61 SIAGSTIAIALALAcMHpevrekf 84  Plasmodium yoelii yoelii
Q8IEU1        67 IASGAIASVAAILG-LGYYGYKKS 89  Plasmodium falciparum 3D7
CDS51324      60 LSSGL---VASIIG-VLYYMYKSh 79  Plasmodium berghei ANKA
Q7RK90        86 LSSGL---VASVIG-VLYYMYKSH 105 Plasmodium yoelii yoelii
XP_001616488  60 VCGSILLAFASLWG-IRIHHTlky 82  malaria parasite P. vivax
XP_002261684  59 IAAAVLAVGGILGG-VGYGIAKQR 81  Plasmodium knowlesi strain H
EDL42975      59 IAATVLAAGGILGG-VGYGIVKHR 81  malaria parasite P. vivax
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap