Conserved Protein Domain Family
Trep_dent_lipo
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pfam09710: Trep_dent_lipo 
Treponema clustered lipoprotein (Trep_dent_lipo)
This entry represents a family of six predicted lipoproteins from a region of about 20 tandemly arranged genes in the Treponema denticola genome. Two other neighbouring genes share the lipoprotein signal peptide region but do not show more extensive homology. The function of this locus is unknown.
Links
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Statistics
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PSSM-Id: 286754
Aligned: 4 rows
Threshold Bit Score: 475.232
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q73QM8   4 NKSKLIFILMLAVLLFSCSKEVKEQKLVEAKVESSIKIEPK-----ENEF---LSKPEYNTHV--------------KSP 61  Treponema denticola
Q73QM2   4 NKLKLIIILILAVLLFSCSKEVKEQNSAETKVESSAKIEPK-----ENEF---LSKPEYNTHV--------------KSP 61  Treponema denticola
Q73QM4   4 DKLKFIFILILAFLLFSC-------KASDTKSGREMRIEKFskmieSNKIsgvSGKGKEDEFV--------------GTP 62  Treponema denticola
Q73QN1  44 DKLKLIFILMLAVLLFSCTKEIKEPAEERNSVVKNEVMEKKpllilEHTI---PSKEEDDEDIdfteeeppivltdeNTP 120 Treponema denticola

Q73QM8  62 --EQIKELEEKykrsKAYEESLKQLRTELDKKEDILR-YKCPVFMSIDNLAQQKASALYshadnldfihfyEVKKDGEFC 138 Treponema denticola
Q73QM2  62 --EQIKELEEKykrsEAYEEKLKQLGAELDKKEKILN-YKFPTGITIDELAQQKAPVLYspadnlefihfyEIKKDGEFC 138 Treponema denticola
Q73QM4  63 --------------------------FVLDDYDLV---Y-------IQALYTRT-----------------NIGKDNRIY 89  Treponema denticola
Q73QN1 121 ktELIKLLESK----KRHAWSLHKIQLEIDMYDVHGNsYEEFEKSGIDYLNRQKNTEIV------------KVDSDNKNI 184 Treponema denticola

Q73QM8 139 Y---------------CKYKAPTQNGGILDYQVTYKWYNIEQMYLPLSYDLLSETNMVKINDELI-------ENQVHGSL 196 Treponema denticola
Q73QM2 139 Y---------------CKYKAPTQNGGTLDYQVTYKWYNIEQMYLPLSYNLLSENNMGRINEELI-------ENQVHGSV 196 Treponema denticola
Q73QM4  90 YtdvevikferekeieCRQKRTAKNGKDFFYSIKYEWDKRAKKFVNTKYELEQELNIGVIDEKII-------KEQVHGIV 162 Treponema denticola
Q73QN1 185 Y---------------CKQTLNLPSGKELIYDAVYTFYPYPKNFAYTNYELR--------DKPIIayrhvpeAKRVHGKI 241 Treponema denticola

Q73QM8 197 YGMENDEKKDEMIKLFEDYENTRyplylevvntdwdtgVKTKKYKQYD--MRILDYVKGNFTNSGYDEYFVMFYEE---- 270 Treponema denticola
Q73QM2 197 YSMENDEKKDEMIKLFEDYENTQyplfkevvhtdwdtgVKTIGYKQYD--MRILDYVKGNFTNSGYDEYFVMFYED---- 270 Treponema denticola
Q73QM4 163 IESKEDPDRESLIPMFESYM------------------TKLDKNDKYHytYYVLDYIRGNFTNSGYDEYIVFFTNDsrke 224 Treponema denticola
Q73QN1 242 TEAAKNPNKNKNIKIFERYINKY---------------TKEHRHKTGDkpYKVFDYVKGNFTGSGKDEYIVLFTAP---- 302 Treponema denticola

Q73QM8 271 ------------DPDPEIYD-------QFIERVRCFVVDEDKIIKDYYITvPSASFFPPHIERGGLFG---------LKN 322 Treponema denticola
Q73QM2 271 ------------DPDPEIYD-------QFIERVRCFVVSEGKIISDYYIS-NSGGFFYPGLSNDKLSE---------VEA 321 Treponema denticola
Q73QM4 225 meeagehhpnfySKDGKLSDit---wkNNICDIACFIVEGSTFKKVYNIYfRGSIFLPAYEKSSSLYGslnprqmpyITN 301 Treponema denticola
Q73QN1 303 ------------FTKSELEDgiflleySYIKYVECFIMENDKVIKMYKLPgHWGHVVPRDKTKIDL-------------- 356 Treponema denticola

Q73QM8 323 FGFEFSQGWVSDFNQNGKNEIYfVTHFSTGRNFLFIIEFNGEFFVTGYVY--GNDYDivGIDWYKKKI----------II 390 Treponema denticola
Q73QM2 322 FGFKFSQGWIADFNQNGINEIYlAAFFNIEGGGLLMVEYNDGSFVTGYVY--GDRYDivSVDWYKKII----------II 389 Treponema denticola
Q73QM4 302 FGKQFFQGWVADLNQNGINEIY-IYFPWKGTVRITMAEFIDKDFEFKCIEilGDEFN--NVDWHKKTFngny---ysiEL 375 Treponema denticola
Q73QN1 357 -GEQFSFGWIADFNQNGINEIF-VHRKEVFGSSFFSIEFIDNRFVEIPITnrGDILK--SVDWEQSKIvvetnpfrslVL 432 Treponema denticola

Q73QM8 391 KDESRSGKWIDD-YQWNDTLKEFIL 414 Treponema denticola
Q73QM2 390 KDKSGNGEWIDD-YQWNDTLKEFIL 413 Treponema denticola
Q73QM4 376 RDDTYGIIWYKEiFQWNEDDDNYWL 400 Treponema denticola
Q73QN1 433 DSKDTRPKYFAE-YQWCEKEHCYVL 456 Treponema denticola
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