Conserved Protein Domain Family
Arb1

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pfam09692: Arb1 
Argonaute siRNA chaperone (ARC) complex subunit Arb1
Arb1 is required for histone H3 Lys9 (H3-K9) methylation, heterochromatin, assembly and siRNA generation in fission yeast.
Statistics
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PSSM-Id: 401581
View PSSM: pfam09692
Aligned: 51 rows
Threshold Bit Score: 322.669
Threshold Setting Gi: 74625367
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003719165 178 TALNKIRG--TGFEDGYADPPMTVEEFEEEK-RIYDPETPFVDRIEECIQRYRGRRRL---DSTRDLMFSRYLNMGGIDT 251 Pyricularia ory...
EMR62883      17 kgGVLGRKnaSGFEEFYADPPVTPAESAEEK-NIYSVSRPFYDRMEECIQRFRAHRRL---NTERTNIFNKYLFMGGIDA 92  Eutypa lata UCREL1
ELR09322     149 SSGKKKKPnpTGFEEFYADPPITPEDHKEEVeQLYHFARPFAERIETCIQRYRARRKL---DEERANIFNKYISFGGIDT 225 Pseudogymnoascu...
XP_008087275  10 KTPKAPKVkpNGFEEFYADPPITPEEAIEERhDLYSPTRPFPDRIQTCIQRYRARRKL---DEIKANCFNKYLILGGIES 86  Glarea lozoyens...
XP_001590633 147 KSGANKKAapTGFEEFYADPPLTPNEYEEER-DVYH------------------ERKL---DSVRSNILTKYFALGGIEV 204 Sclerotinia scl...
CCD52608     146 SGGKKKAAgpTGFEEFYADPPLTPDEYEEEC-DIYHKGRTFAARIETCIQRYRARRKF---DSTRANILTKYFALGGIES 221 Botrytis cinere...
XP_007291144 135 GSGKNKKApvTGFEEFYADPPITPAEQEEEE-DLYEWSRPVPERIETAIQRYRGRRKL---DEHRSNILTKYLMLGGVEA 210 Marssonina brun...
EPS43523      63 RKGGKGKTlpTGFEENFAEAPLTPAIFNQNK-ELYNPSKTVAERIETAVQKYKAKRKFsgaNVIRDQILRDYLLLGGINT 141 Dactylellina ha...
XP_011117667  74 RKGGKGKTlpSGFEENFVEAPLTAEEYNKDK-ELYSAKKTVAERIETAVQKYKAKRKL---DPLRHQLLEAYYHLGGIKT 149 Arthrobotrys ol...
CCX32453      64 RTRKIGHTkpSGWEEYCVDGPLPLSVVQEEL-ELYSPKKPFIARIELCIQRYKAKRKW---DTLRLQMFTNYLTLGGVSS 139 Pyronema omphal...
XP_003719165 252 SQRQFTGAngISKEDLAGLSKAEKRMAAANDVINRRgD---DPRWFTPGdE----GWTVDFAGVVAAYLSTRLPFDVAGE 324 Pyricularia ory...
EMR62883      93 HPRQFTG---MDPGTLADADKDEIRTMTAVDFIGGA-----GSRYFEIGdEe---HWEIDFEGVVKGFLSRTIPDIYMYD 161 Eutypa lata UCREL1
ELR09322     226 TIKAFTGG--VDNEALEDFDGPTIADINATDVMYGGdEa--GSKFYDPCaPq---NWVVDFEGIAKAFLA---PYNFGIH 295 Pseudogymnoascu...
XP_008087275  87 TNKAFTGGa-LDDETLATTTADEIAAIQATDFVRPG-----NKKYYDPAeSd---KWIVDWEGVAKGFL---IPTQLEME 154 Glarea lozoyens...
XP_001590633 205 GTKTFNGG--LDKETLENSTAAEIAAIQATDFVRSS-----NSKYYDPSdTe---NWVVDWEGVVKGFLA---PKIMG-D 270 Sclerotinia scl...
CCD52608     222 GAKTFNGG--LDQETLDNSTAAEIAAIQATDFVRAS-----NAKYYDPSdTe---NWVVDWEGVAKGFLSYRAPRILG-D 290 Botrytis cinere...
XP_007291144 211 TAKAFTGG--LDKETIENSTAAEIAAIQASDYVQAGtK---NSKYYDGSd-----DWVVDFEGVAKGFFSHRVPRIFPLD 280 Marssonina brun...
EPS43523     142 AQKQFGG---VDQKFIREHDAEEIARFTATDYVPDKmKnigVERIEELDdDfeepEYEVDFNYVVRGFLTHRVPFSFGMK 218 Dactylellina ha...
XP_011117667 150 GAKMFGG---LDQKFIKENDTEEIARFKATDYVPESmKnigIQRVEELDdDyedpEYTVDFDYVVRAFVTHKIPFDFGMK 226 Arthrobotrys ol...
CCX32453     140 GQKQFSGG--LDPKKIDEMDAEDIAAITATEFINVGqAggdDD------------EWDVDFELVARGFLSYKVPHVMGIS 205 Pyronema omphal...
XP_003719165 325 -QDMMALGVDTILNFINYVIKHDVCPEYEADLARARAVCKLAKIEFPLINRALAGGMGQFNYACRTIFNL---------- 393 Pyricularia ory...
EMR62883     162 -PSAFEKAADLIKNFLNYVLMHNACPEYTDNIMAARNICDIFLPEMRATHELLDELPGSFNSAAAALFCG---------- 230 Eutypa lata UCREL1
ELR09322     296 nQGLVNNYCNVVKNFLNYVLMHGVCPEYTKSIIAAQKVCDLAKFELPAIHDVGASFPGNFHKALSIMCHGcsrllyidpa 375 Pseudogymnoascu...
XP_008087275 155 sEQLIKLYCAVIKNFLNYVLQHEVCPEYVEDVMAARRICGQAEEELNAIRRLGKKLPGNFNIALSTLFGGvyfg------ 228 Glarea lozoyens...
XP_001590633 271 gEDGVKMYCAVLRNFLNYVLAHEVCKEYTKDVMAARKICDIAEREYHSIRYLRQMFPGDFNVAASTLFGEyhkqhmeina 350 Sclerotinia scl...
CCD52608     291 gAEEVTMFCGVVKNFLNYVLAHEVCKEYTKEVMAARRLCDVAEREFDAIRCLRQMFPGDFTVAASTLFGEnykrhfeins 370 Botrytis cinere...
XP_007291144 281 cEKDIMAITNVIRNFLNYILQHEVVPEFTKDIMAARALCDLAEQELWAIHVLNFKLPGDFGIAASTLYGGrfkglclene 360 Marssonina brun...
EPS43523     219 tTENIDIAVGTIRNFLNWIIYHNVCPEHTDNLKLALKTCDMAAQELPICSILSDQFPGELNKACSTLFGGywsmitpqsw 298 Dactylellina ha...
XP_011117667 227 sPEQIEKAVNTIKNFLNYILYHNVCPEYTDNIKQAVKTCDKANEELPICAALSDKFPGDFNKACSTLFGGywsymtprew 306 Arthrobotrys ol...
CCX32453     206 kEKELMTAVNIVRNFLNYVIAHNVAPEYEANIRAALKICDLAEQELVLCLNLTTRLPGTFNTACSTIYQGhyqnlgdedm 285 Pyronema omphal...
XP_003719165 394 -----SDET---DCFVDRMSVDPARnrpvrpiLVFTSTLTLLADMYPAARTIdlhklrdedptmdklAGAISSESRADYY 465 Pyricularia ory...
EMR62883     231 ---------------DRTVDNLDKQenfdklvNFRLIALETTTNEEVRKKlakl----------ddpAIVRDSETKEETY 285 Eutypa lata UCREL1
ELR09322     376 s----ipdhpadadpNQYMSIDQAH-------RTFRAAMALMGTAEQFAAVAvtsl--------keyQAPAVVSEELRGF 436 Pseudogymnoascu...
XP_008087275 229 -inqaDQPW---QEHAIGMTVEKAE-------EVLKKGVQALDalgy-----------------vwkKADIVVISSTRDY 280 Glarea lozoyens...
XP_001590633 351 awvdvedgseqwctnVPLLSLPVCR-------FVFGGIVAFLGNKShfek--------------akkGDAQVVDIENKFI 409 Sclerotinia scl...
CCD52608     371 awanpeddlsqwntnIPVLSLPVCQ-------FVFGGIVAFIGDKShfdk--------------aknGDIHVVTIETRFI 429 Botrytis cinere...
XP_007291144 361 gwvkedpnfaemmslNQGFSDEKAS-------RIFMTSVAFAGDDElfvk--------------tseGNLRIVKTEVKFL 419 Marssonina brun...
EPS43523     299 ekvdgEE-I---KKTEPGVSYERAR-------STYQALLPELpfqn------------------esgDLPTEVYREYGSF 349 Dactylellina ha...
XP_011117667 307 ekvdgELDF---KKPEPGLSKEKAS-------EIYHALVCELPhitf-----------------disKTPREVYREYASL 359 Arthrobotrys ol...
CCX32453     286 -----swmpeeerhrSIFFTREEAT-------SLVETALKKRGTpeqq----------------algVGRKVVKRHFLSV 337 Pyronema omphal...
XP_003719165 466 EVVETREPSEPIARLFRALHSGDKVTG--HYKPAGVLVVRRciv------edgFANtPKLHMMPLtrg----------kd 527 Pyricularia ory...
EMR62883     286 EVYEIARPRRQYIKMFEEQLKQMQMPG--KVKPAGRVLLKPaii------ehsYDNlPRPDDVDLsg------------a 345 Eutypa lata UCREL1
ELR09322     437 EVVGITLPGEALSKSFAGIRAADGRTG--TIKPVGLLACNS------------WTH-PYQPTLDLtieeeqglaanppvy 501 Pseudogymnoascu...
XP_008087275 281 EVTAIELPKE-------------------EDGMLGFFKCKP------------WEG-PQSDVYEApnktp-------lst 321 Glarea lozoyens...
XP_001590633 410 EVVDVHLATANIVAEFSRVKDPRGLG---ALKPVGKLLCKS------------WEG-PGYDYEDKtddgne-----vvdd 468 Sclerotinia scl...
CCD52608     430 EVADVHRASANVVKEFSHVKDPRGLG---ALKPIGKLLCKS------------WEG-PGFAYEDKtddgid-----eldd 488 Botrytis cinere...
XP_007291144 420 EAIKIKRASVESIETYAGVTDHEGKPG--KIKPLGSIWYKA------------WEG-PGFDDEDLtdeeieaakialata 484 Marssonina brun...
EPS43523     350 EVISTWLPEPGSPLI------------------LGKIHCQSwtpeesspieskWGG-PD--------------------- 389 Dactylellina ha...
XP_011117667 360 EVVSVWLPKPGSPLK------------------LGRIVCKSwtpeealpitskWSE-PN--------------------- 399 Arthrobotrys ol...
CCX32453     338 QVIEVYNPPSEWVQDKDADKTLPENKYyqKTQTLGWIKVKPwvp-----------edPYVIPEELpld----------ql 396 Pyronema omphal...
XP_003719165 528 dVASFIVDRDLLRCLLPGMNLHLETARIthpDFELTIVKNLLDVQPSFRLFLPQMLMLDYKMP 590 Pyricularia oryzae 70-15
EMR62883     346 pVEEYLVEDEILAKLQRGMKLKLVVCEL---NIGIRFIKEVHDIRVSFDTFLPQTLMAGWKDP 405 Eutypa lata UCREL1
ELR09322     502 gDETFWVDEDILERCFAGMKFVGVVREL---DLGVRYLDNVIVIYASFYTFVENERMVNWKAP 561 Pseudogymnoascus destructans 206...
XP_008087275 322 qEETFYVDADIIELIQVGMKVEMIVREI---DNGFKFFDHA-GFFCSFYTCLENEKMVDWKEP 380 Glarea lozoyensis ATCC 20868
XP_001590633 469 sVEEFWLEDEILQHCYPGLKLEVVVHEL---NIGVKYFDQVIDVFPSFHLYLPNEKMLGWKEP 528 Sclerotinia sclerotiorum 1980 UF-70
CCD52608     489 sIEEFWIEDEILQQCYPGLKLEVVVHEL---NIGVKYFDQVVEFFPSFHLYLPNEKMMGWKEP 548 Botrytis cinerea T4
XP_007291144 485 pVEKFWLEDDILQDCFEGMKIEATVHEL---NTGLKFIDSFKGVFCSFHTILPNEKLVGWKEP 544 Marssonina brunnea f. sp. 'multi...
EPS43523     390 -GLTLYCEKIIAQYVYPKMHICCTLHEL---DNGFIYFDEITGVMCSDFLEIRDD-----KEL 443 Dactylellina haptotyla CBS 200.50
XP_011117667 400 -NLTLYCEKTVAQYAYPKMHFGCTVHEL---DYGLVYFDEISGVMCSNFLEIRDD-----KEL 453 Arthrobotrys oligospora ATCC 24927
CCX32453     397 dEITIWLEKTVVQWCFVGMKMATKIHWF---EDGLVFMDDVTGLYTSFYLPLENpkedegddd 456 Pyronema omphalodes CBS 100304
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