Conserved Protein Domain Family
Fib_succ_major

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pfam09603: Fib_succ_major 
Fibrobacter succinogenes major domain (Fib_succ_major)
This domain of about 175 to 200 amino acids is found, in from one to five copies, in over 50 proteins in Fibrobacter succinogenes S85, an obligate anaerobe of the rumen. Many members of this family have an apparent lipoprotein signal sequence. Conserved cysteine residues, suggestive of disulfide bond formation, are also consistent with an extracytoplasmic location for this domain. This domain can also be found in small numbers of proteins in Chlorobium tepidum and Bacteroides thetaiotaomicron.
Statistics
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PSSM-Id: 401514
View PSSM: pfam09603
Aligned: 58 rows
Threshold Bit Score: 79.7945
Threshold Setting Gi: 557033574
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CCZ43752       158 YGSKTWMTMNCFESG-Ndgklg-taidITGITVKGMTE-AALSEINDKA--------------GRFYTWYEamtgipact 220 Bacteroides s...
ESQ11269       226 aAGRVWMDRNLGAHRa-----------------------AETFNDCRAY--------------GNNFQWGRladghheie 268 uncultured De...
WP_015548072   150 YGKRWWMTENCHEAG-Edgnlg-vapdLTAFSVAGLEA-SHLQRLNDAK--------------GRYYTWYEamtgisgct 212 Alistipes
Q8A1C6         408 IAGNVWMAFNARSRD-Ledq----iypLDGATVE------------DMYhkswintvgglfqfGRLYMYVPwqgynpsnn 470 Bacteroides t...
Q15RK4          44 IGEQIWLAENLRVTK-Y----------QDGTKINTGFIpDDKEENLLKH--------------GRLYDWHDvv------- 91  Pseudoalterom...
CDA75170       246 YGNCIWMVENFRYVPaErlnkgiwvqgYNGSSAEEAMQ----SENYSVY--------------GCLYDYQT--------- 298 Bacteroides s...
WP_014033847    51 IGTQVWMAENFAYLP-EvdtmnisvygYKGNSVKEAKR----SKYYKKY--------------GALYSWEK--------- 102 Muricauda rue...
CDD82936        47 IGDQEWTTENARNGSrvwnveyyvpd---ygwyetisfdADTTDYFNEY--------------GNLLSYEE--------- 100 Bacteroides s...
WP_013612748    49 YAGLDWMTSNFKEGT-Pyyelt-yinqYGYTDDLIKDCeDLTPEEWDRY--------------GNLYSYEE--------- 103 Odoribacter s...
jgi:Odosp_0316  53 IGNLEWMTENCRYRT-Sdckyyvd--------ygntgqtNPSDVYSDRY--------------GFLYTLLD--------- 100 Odoribacter s...
CCZ43752       221 keqyeekiasy-------------------ggkddagnaftldgteggeyNVQLrgcCPEGWHVANCNDWwDL-L--HAI 278 Bacteroides s...
ESQ11269       269 wysdssaarlngstatgtsfnndqpptdqfivpsgsyqydwrnpknddlwQDGLndpCPTGFRLPTTEEW-QA-EtaAAG 346 uncultured De...
WP_015548072   213 aeqcpyvqnye--------------------gvddvgnafkldgteegefGVQIrgcCPEGWHVANANDWwDM-L--MAI 269 Alistipes
Q8A1C6         471 l----------------------------------------gnqtadapwVNDThmpCPEGYRIPTGNEW-QSlLpaDQE 509 Bacteroides t...
Q15RK4          92 -------------------------------------------------dERNI---CPVGWRIASDDDW-KA-LekSIG 117 Pseudoalterom...
CDA75170       299 --------------------------------------------------AKDL---APEGWHLATDAEW-NE-LekLAG 323 Bacteroides s...
WP_014033847   103 --------------------------------------------------ANEL---APKGWRLPTDKDW-IL-LetTVG 127 Muricauda rue...
CDD82936       101 --------------------------------------------------ALAS---APEGWRLPTDDDW-KK-LerAMG 125 Bacteroides s...
WP_013612748   104 --------------------------------------------------AKAN---APEGWRLPTDEDW-KK-LerAMG 128 Odoribacter s...
jgi:Odosp_0316 101 --------------------------------------------------APNA---VPEGWRIPTDEDF-KQ-LerALG 125 Odoribacter s...
CCZ43752       279 KSEYnvgediykgefsfnggclatl-pgvtkdefykngstvknmgnVGAWLRGGngrlvdggvwnqtnetlkdkdAAGPI 357 Bacteroides s...
ESQ11269       347 IEDGyd---------------------------------------aFNSTLKMT-------------------------- 361 uncultured De...
WP_015548072   270 KSEYaipddfaqggytfsgghdgkpenaitkagfyksgctvkntgnVGAWLRGGngrivdggiw--nqanmtltdAGEPL 347 Alistipes
Q8A1C6         510 I---------------------------------------------PGRYKAGNgetiaatlhigegtlitpssgVTGTQ 544 Bacteroides t...
Q15RK4         118 ISESeldtlg------------------------------wrgdndIAITLKAEq-------------------qDTIFK 148 Pseudoalterom...
CDA75170       324 VPEGllmeee-------------------------------dwrgnSNDRLKAE------------------------TW 348 Bacteroides s...
WP_014033847   128 MSRDeavkeg------------------------------wrgtsnSVAYLREN-------------------------- 151 Muricauda rue...
CDD82936       126 M-GGeadqt--------------------------------gwrgsIASLLTRS-------------------------- 146 Bacteroides s...
WP_013612748   129 MSQGdadatg-------------------------------frgteEGTLLQQD-------------------------- 151 Odoribacter s...
jgi:Odosp_0316 126 MSAAnadeld-------------------------------wrgggTGTLMRQA-------------------------- 148 Odoribacter s...
CCZ43752       358 VQFVSGADEVGF-------GW--YPAG-RIEIDGVt---iNAKAPGKYGFLWFIGQQDADYARSLCisgtsmnlnmm--- 421 Bacteroides s...
ESQ11269       362 --------FTGYwgvydyqQTniRHAG-D-----------PANDSDSEGNYWSSSPATShggrgahnfyftr-------- 413 uncultured De...
WP_015548072   348 LQFVDGAESIGF-------GW--YPLG-YQKADGSf----NSGALGKWGYVWFIGQTNASTARSlvisgtslnlq----- 408 Alistipes
Q8A1C6         545 HYVKFTSEDTGR-------SLiiPLAG-SKGDKSSs----NNPAFGKRAVLWTNERNGLPGGYAWAywlpfegaett--- 609 Bacteroides t...
Q15RK4         149 GFDQSQVNKYQF-------SA--SPAG-VKIGN-------WYLTQGMYTEFWTGSSATEKQAYARTlayswwnthkg--- 208 Pseudoalterom...
CDA75170       349 QGNGNWSNELGF-------NI--HPGG-KQWCGG------AFQDFKQAGLYWTSTMNDHradgalqpffrwfsg------ 406 Bacteroides s...
WP_014033847   152 -------GGAGF-------DVqlA--G-WRTDYG------DFRFMGEHANFWVADSHDSERAFERMigatntkig----- 203 Muricauda rue...
CDD82936       147 ------DQGAEL-------GL--KLGGsVLYSSETygvgcLLKYDGEAGYYWTSTVDESksggdgyrmvffrklv----- 206 Bacteroides s...
WP_013612748   152 ------ITGTGI-------AL--PFGG-YAIVTGRpa-alRFRHWREFGYFWTATEeknetpfpdayyrkisfrssqier 214 Odoribacter s...
jgi:Odosp_0316 149 ------EEGTRL-------NF--QLAG-YYTPYMImq-tpGYRFMGAYGFYWTSTKDESKNGeyyfyrklyyesd----- 206 Odoribacter s...
CCZ43752       422 -----ntkrveanklsRLNVRCV 439 Bacteroides sp. CAG:545
ESQ11269       414 ----syishggpyrgyGLSVRCI 432 uncultured Desulfofustis sp. PB-SRB1
WP_015548072   409 -----tktnqeaakdiYLNVRCV 426 Alistipes
Q8A1C6         610 -----vikkqrlqmeaFASVRCV 627 Bacteroides thetaiotaomicron
Q15RK4         209 -----eirreklnknyMFSVRCV 226 Pseudoalteromonas atlantica T6c
CDA75170       407 --gpatgrfsnfpecvGMSVRYV 427 Bacteroides sp. CAG:530
WP_014033847   204 --------reqgnkgcGFSVRYV 218 Muricauda ruestringensis
CDD82936       207 sgqegverqsgnnsnkYMSVRWV 229 Bacteroides sp. CAG:462
WP_013612748   215 gitrivdsnyetnypkHMSVRYV 237 Odoribacter splanchnicus
jgi:Odosp_0316 207 ----qvyrqsiennaqYLSLRLV 225 Odoribacter splanchnicus DSM 20712
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