4RCT


Conserved Protein Domain Family
RE_NgoFVII

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pfam09565: RE_NgoFVII 
NgoFVII restriction endonuclease
This family includes the NgoFVII (recognizes GCSGC but cleavage site unknown) restriction endonuclease.
Statistics
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PSSM-Id: 401488
View PSSM: pfam09565
Aligned: 14 rows
Threshold Bit Score: 291.647
Threshold Setting Gi: 503784040
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4RCT_A                 43 MDLFKSADEVLMATGYVSNDAvvelHKIL-ElND--HIQKIDLLVGMHYlEGFSHLQYDSLXKLNDFLrhekrGAVYVSP 119
CCY26068               23 YSLLPKTSKLDIAVGYVSADSlielQKTIeL-NS--NIRTLNLIIGMHYfDHFTKVQYDAAMHLNDFLagnqmGGVRLVN 99  Firmic...
Q5F9M9                 23 MDLFKSADEVLMATGYVSNDAvvelHKILeL-ND--HIQKIDLLVGMHYlEGFSHLQYDSLCKLNDFLrhekrGAVYVSP 99  Neisse...
jgi:HSM_0597           23 TDLFMSSDEVLMTTGYVSNDAvkelHKILeH-NQ--SIQTVKLLVGMHYlEGFSQLQYDSLCELNQFLqqeqrGAVYVSP 99  Histop...
Q8NPN4                 25 DKELKDTHHLDITVGYISEKSlqylLLIA-G-TH--PDLTITLTCGMHArEGMTAAQLHHARVLHDYLsdhdrGGVFVIP 100 Coryne...
WP_012869707           13 EPISRGAEELLIVSGYATPTMaswhMTRI-K-ELsmPLIGIKLIVGMTNyDGLTKDVHEGFKQLVYTQsntalSKFQCQY 90  Therma...
jgi:Desgi_3514         13 EPITRGAQQLLLLSGYATPTMaswhMMKI-K-ELeiNPIDIKLIVGMTNyDGLTIDAHEGFRQLVNAQngsgfSSFQCQY 90  Desulf...
Prjna32935:ECBG_03022  15 HDLIEEPDELIIISGYLGPAP----IERL-K-EL---PMSVTVIGGMYP-TGIDARLHHAIEQIKNEN-----KKLTVKY 79  Entero...
CDA75052               14 SDIAKNSNKLFVISGYVGAEI----IKTL-S-SFp-SNIQFEVIYGMYGcDNISEPLHKKLVELDKKL-----PNVSISY 81  Bacter...
CCZ11762               15 LHNTTSSNNIVIVSGYVGYQT----IKML-C-EQc-CDVRITVVYGMYGsERISQPLHLALMEVQRQY-----SNITILY 82  Prevot...
4RCT_A                120 FV---KFHGKMYSFKNYqK--INGLIGSANLTCFWD-STeRTYETMLHlNGK-PAQILQADIQSTIHK------LGKNIQ 186
CCY26068              100 AF---RYHGKLYSYSNA-TgpFAGIVGSNNLSSIVDgGV-RMYESSVLlNDEvSAKQINAFIRQLMQT------STRNIA 168 Firmic...
Q5F9M9                100 FV---KFHGKMYSFKNY-Qk-INGLIGSANLTCFWDsTE-RTYETMLHlN-GkPAQILQADIQSTIHK------LGKNIQ 166 Neisse...
jgi:HSM_0597          100 FV---KFHGKMYSFKNR-Ne-IQGLIGSANLTCFWDkTE-RTYETMFHlE-KlPAISLRTDIQTTISK------LGKHLE 166 Histop...
Q8NPN4                101 RL---RYHGKIYLFHKNqHtdPIAYIGSANLSAIVPgYT-STFETGVI---------LDPAPEDLVLH------LNRDVV 161 Coryne...
WP_012869707           91 ICqgpPVHSKLYIWMKNgEp-VEAYTGSANYTQAGF-SL-GRREYIVPcNAYdAFS----YFCSVERDs-----IYCTHS 158 Therma...
jgi:Desgi_3514         91 ICqgaPVHSKLYIWLKDdKp-FEAYTGSANYTQAGF-ST-SRREYIVPcNPEgAFD----YYNQVECDs-----IYCTHS 158 Desulf...
Prjna32935:ECBG_03022  80 STq--EIHSKIYIWKQKgRi-LSALIGSANFSSNGL-RT-AYRESLAD-ATRdTFSPLDEYYQFILNNssehpvIKQKQV 153 Entero...
CDA75052               82 STv--PIHSKIYCWFVNdKv-SGGLIGSANFTINGL-RK-DYKETLCDiQ-EsNYDEYQKYFKYVREHs-----IPCNEG 150 Bacter...
CCZ11762               83 STi--PVHSKIYTWNCDaKi-EKALVGSANFSISGM-MN-DYKEVLSDvE-QdTYSTLKEYCDYVLSKa-----ISCNDA 151 Prevot...
4RCT_A                187 EVERpskfie------hnshlENXLGVQKIAPe-------QirqlfaqTSEYHFSIPAK---TEEKS--NLNVFFGEG-- 246
CCY26068              169 ELEIdtfnn-------enallDGHEFVEKVAPqnlakainA-------KTDISFEIPIKpyeVSPQS--NLNAFFGKG-- 230 Firmic...
Q5F9M9                167 EVERpskfie------hnshlENCLGVQKIAPeqirqlfaQ-------TSEYHFSIPAK---TEEKS--NLNVFFGEG-- 226 Neisse...
jgi:HSM_0597          167 EAKRpdhfrd------hninlAQCLGVQKVSPehlvsyfeK-------TSQYKFEIPAK---TEPKS--NLNVFFGDP-- 226 Histop...
Q8NPN4                162 PLCVpidtahvpiikdqespmKHVAEATAVSTsdvvaimsS-------PFTYSFDLKLK---ATASS--NLNAHNSGGg- 228 Coryne...
WP_012869707          159 EVEEniilq-------pinpvLEAENGHVQIVk-------G-------QGVEHVKLSLL---A-RDG--ETGRRSGLNwg 211 Therma...
jgi:Desgi_3514        159 EVEDnivft-------pthpvLESESEYTQALr-------G-------EGIEPIKLSLL---A-RNG--ETGTRSGLNwg 211 Desulf...
Prjna32935:ECBG_03022 154 EIDL------------------SVSNKQSEVDi-------Q-------NIVYTVHIPLY---SFVGKqkVVMPKSGLNwg 198 Entero...
CDA75052              151 KISFkks-----------rhlMEKNGTKN--Qp-------Y-------LSEGICRMSLL---T-ENG--LVPQKSGLNwg 197 Bacter...
CCZ11762              152 EVKFqk--------------vFKASGHSKLVQp-------L-------LAKNVCRATLL---D-RNG--MVSKKSGLNwg 197 Prevot...
4RCT_A                247 --------------RRDKRGFVKPRPWYEVELIVSkditsqEGYPVLKS----FTVITDDGWQFQC----KTSGD----- 299
CCY26068              231 --------------RESKNGLVKPRHWYEVELIVPknvtsqPGYPQSQTdnavFTVITDDGWSFKC----KVSGD----- 287 Firmic...
Q5F9M9                227 --------------RRDKRGFVKPRPWYEVELIVSkditsqEGYPVLKS----FTVITDDGWQFQC----KTSGD----- 279 Neisse...
jgi:HSM_0597          227 --------------RVGRK--VLPRPWYEVELIIPativrqEGYPTNRK----IQVITDDGWLFPCyskpKNKGEk---- 282 Histop...
Q8NPN4                229 -------------aRKQKNGSFLARNWYEGEIIVGvettrlPGYPQNKSe---FTAVTDDGWSFVC----KISGG----- 283 Coryne...
WP_012869707          212 qregre-pnqayipLPAEIARS--GFFP--------------------LqkrhFSVITDDNKHLIL----RVEQQ----- 259 Therma...
jgi:Desgi_3514        212 qrdgre-pnqayigLPASIARS--GFFP--------------------LekqhFSVVTDDNKQLIL----RVEQQ----- 259 Desulf...
Prjna32935:ECBG_03022 199 lskghvapgdgyirIPKSIYQQQQNLIKPFDEDFI------TPKGKKKRnsdpIELLWDDGMVMPA----SFEGVqqvn- 267 Entero...
CDA75052              198 cskghvspgdayikISTDYIRKFPGIFPQ--KKYVsgipnlDSKGKPNRendeVELIWDDGTSMVG----LMEGQiqid- 270 Bacter...
CCZ11762              198 lsnghvsegdayirITSNYIKLFPSLFPP--KKYVgmd-npLSNGKKNRendeVELIWDDGEKMIG----LLEGQqtkti 270 Prevot...
4RCT_A                300 ----YSKNFRSEND------------LKTLGKWIKGRLE 322
CCY26068              288 ----YSKNFRSEGD------------LKILGKWLKGRLE 310 Firmicutes bacterium CAG:114
Q5F9M9                280 ----YSKNFRSEND------------LKTLGKWIKGRLE 302 Neisseria gonorrhoeae FA 1090
jgi:HSM_0597          283 ---lSTENFRSEND------------LKTLGKWIKGRLE 306 Histophilus somni 2336
Q8NPN4                284 ----NGKNLRSKGD------------LSILGTWLKSRFI 306 Corynebacterium glutamicum
WP_012869707          260 ----NDKAITTPMN------------NSLLGEYFRNRIG 282 Thermanaerovibrio acidaminovorans
jgi:Desgi_3514        260 ----NDKAITTPMN------------NSLLGEYFRNRIG 282 Desulfallas gibsoniae DSM 7213
Prjna32935:ECBG_03022 268 -gkrYPKQLASYSAkqpyldgqriskKSILGRYIRNRLG 305 Enterococcus casseliflavus EC20
CDA75052              271 -gviYPKQLSTSPS------------KNILGKYLRKRLG 296 Bacteroides sp. CAG:530
CCZ11762              271 nglvYPKQLSTSPS------------KSILGKYLRKRLG 297 Prevotella sp. CAG:1092
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